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您的检索式：作者名="Iclal Yucel"
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| 1 | Effects of resveratrol and methylprednisolone on biochemical,neurobehavioral and histopathological recovery after experimental spinal cord injury显示文摘瞄准:在损害(SCI ) 在老鼠建模的试验性的脊髓调查 resveratrol 的 neuroprotective 效果。方法:男 Wistar 白鼠称 200-250 g 被使随机化进六个组。重量落下损伤为 SCI 被执行。组 1 独自经历了椎板切除术。组 2 经历了 SCI 跟随的椎板切除术。3, 4, 5,和 6 经历了的组 SCI 跟随并且收到了 resveratrol (100 mg/kg ) 的椎板切除术,甲基氢化尼松(MP )(30 mg/kg ) ,加 MP (30 mg/kg ) 的 resveratrol (100 mg/kg ) ,和乙醇(2%) 分别地。老鼠为生物化学的分析被划分成二亚群(在外科以后在 24 点杀死了 h ) 并且为 neurobehavioral 和组织病理学说的评估(在外科以后在 6 点杀死了星期) 。在外科以后的 Posttraumatic 神经病学的恢复每周被记录。结果:3 和 5 揭示了的组显著地比组织 4 降低 malon-dialdehyde,氮的氧化物,黄嘌呤氧化酶,和更高的谷胱甘肽层次(P<0.05 ) 。神经病学的恢复率显著地更好在比组织 4 组织 3 和 5 (P<0.05 ) 。当针的损伤尺寸比率被比较时,在治疗组之间没有有效差量。结论:Resveratrol 处理比 MP 处理在损伤的尖锐阶段揭示了更好生物化学的恢复。尽管 resveratrol 和联合处理比 MP 处理揭示了更好的 neurobehavioral 恢复;resveratrol, MP,和联合处理形式在实验的最后的阶段在一样的水平改进了组织病理学说的恢复。当每药有行动的不同抗氧化的机制,与 MP 包含 resveratrol 和不同剂量联合的不同剂量的未来研究能答应更好的结果。 | Ozkan ARIES Suleyman CAYLI Eyup ALTINOZ Iclal GURSES Neslihan YUCEL Ayhan KOCAK Saim YOLOGLU Yusuf TURKOZ | 2006 | Acta Pharmacologica Sinica2006，27，10： | 18 |
| 2 | Epidemiological and clinical features of paediatric open globe injuries in southwestern Turkey显示文摘AIM:To evaluate the epidemiologic,anatomic,and clinical features of open globe injuries in children.METHODS:The medical files of patients under the age of 16 who had been operated for an open globe injury at Akdeniz University Hospital's Department of Ophthalmology were retrospectively evaluated.RESULTS:A total of 90 patients were evaluated in this study.Among these patients,26(28.9%)were female and64(71.1%)were male.The mean age of the patients was7.7±4.2 years.The male/female ratio was observed to increase with increasing age(P=0.006,P=7.48).Injuries were most likely to occur in spring and autumn(P=0.028).The time interval between the injury and the surgical repair was 9.36±27.4h.Forty(44.4%)of the injuries occurred in the home,27(30%)occurred in the yard,and 21(23.3%)happened while playing in the street.The most common causes of injury were sharp metal objects(P<0.001).Injury to the cornea occurred in47(52.2%)of the patients(P<0.001).The most common complication to occur was cataract formation.Additional operations were necessary for 37(41.1%)of the patients.The final visual acuity was correlated with both the initial visual acuity of the wounded eye prior to surgery and the length of the wound(P<0.001,r=0.502 and P<0.001,r=-0.442,respectively).CONCLUSION:Open globe injuries that are suffered in childhood generally occur either at home,in the yard,or on the street,with sharp metal objects being the most common cause of injury.The initial visual acuity and the length of the wound are the most important determinants of the final visual acuity. | Hatice Deniz Ilhan Ahmet Burak Bilgin Ash Cetinkaya Mustafa Unal Iclal Yucel | 2013 | International Journal of Ophthalmology(English edition)2013，6，6： | 3 |
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