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| 1 | Hepatocellular carcinoma: Epidemiology, risk factors and pathogenesis显示文摘Hepatocellular carcinoma (HCC) is the commonest primary malignant cancer of the liver in the world. Given that the burden of chronic liver disease is expected to rise owing to increasing rates of alcoholism, hepatitis B and C prevalence and obesity-related fatty liver disease, it is expected that the incidence of HCC will also increase in the foreseeable future. This article summarizes the international epidemiology, the risk factors and the pathogenesis of HCC, including the roles of viral hepatitis, toxins, such as alcohol and aflatoxin, and insulin resistance. | Asmaa Ibrahim Gomaa Shahid A Khan Mireille B Toledano Imam Waked Simon D Taylor- Robinson | 2008 | World Journal of Gastroenterology2008，14，27： | 78 |
| 2 | Assessing the relationship between the rumen microbiota and feed efficiency in Nellore steers显示文摘Background:Ruminants rely upon a complex community of microbes in their rumen to convert host-indigestible feed into nutrients.However,little is known about the association between the rumen microbiota and feed efficiency traits in Nellore(Bos indicus)cattle,a breed of major economic importance to the global beef market.Here,we compare the composition of the bacterial,archaeal and fungal communities in the rumen of Nellore steers with high and low feed efficiency(FE)phenotypes,as measured by residual feed intake(RFI).Results:The Firmicutes to Bacteroidetes ratio was significantly higher(P<0.05)in positive-RFI steers(p-RFI,low feed efficiency)than in negative-RFI(n-RFI,high feed efficiency)steers.The differences in bacterial composition from steers with high and low FE were mainly associated with members of the families Lachnospiraceae,Ruminococcaceae and Christensenellaceae,as well as the genus Prevotella.Archaeal community richness was lower(P<0.05)in p-RFI than in n-RFI steers and the genus Methanobrevibacter was either increased or exclusive of p-RFI steers.The fungal genus Buwchfawromyces was more abundant in the rumen solid fraction of n-RFI steers(P<0.05)and a highly abundant OTU belonging to the genus Piromyces was also increased in the rumen microbiota of highefficiency steers.However,analysis of rumen fermentation variables and functional predictions indicated similar metabolic outputs for the microbiota of distinct FE groups.Conclusions:Our results demonstrate that differences in the ruminal microbiota of high and low FE Nellore steers comprise specific taxa from the bacterial,archaeal and fungal communities.Biomarker OTUs belonging to the genus Piromyces were identified in animals showing high feed efficiency,whereas among archaea,Methanobrevibacter was associated with steers classified as p-RFI.The identification of specific RFI-associated microorganisms in Nellore steers could guide further studies targeting the isolation and functional characterization of rumen microbes potentially important for the energy-harvesting efficiency of ruminants. | Déborah Romaskevis Gomes Lopes Márcio de Souza Duarte Alex J.La Reau Ibrahim Zuniga Chaves Tiago Antônio de Oliveira Mendes Edenio Detmann Cláudia Braga Pereira Bento Maria Eugênia Zerlotti Mercadante Sarah Figueiredo Martins Bonilha Garret Suen Hilário Cuquetto Mantovani | 2021 | Journal of Animal Science and Biotechnology2021，12，4： | 3 |
| 3 | Insulin-like growth factor-I and cancer risk 显示文摘 | Ibrahim YH Yee D | 2004 | Growth Horm IGF Res2004，14，4： | 1 |
| 4 | One-step competitive immunoassay for cadmium ions:development and validation for environmental water samples显示文摘 | Darwish Ibrahim A Blake D A | 2001 | Analytical Chemistry2001，73，8： | 1 |
| 5 | Long term effects of salt on activity, population structure and floc characteristics in enriched bacterial cultures of nitrifiers 显示文摘 | MOUSSA M S SUMANASEKERA D U IBRAHIM S H | 2006 | Water Research2006，40，7： | 1 |
| 6 | Bone and cancer:the osteon-cology显示文摘 | Ibrahim T Mercatali L Amadori D | | 0，，02： | 1 |
| 7 | Development of Glass Fiber Reinforced Plastic Poles for Transmission and Distribu- tion Lines显示文摘 | Ibrahim S Polyzois D Hassan S K | 2000 | Canadian Journal of Civil Engineering2000，27，5： | 1 |
| 8 | Densification of alumina produced by urea formaldehyde sol-gel polymeric route显示文摘 | Ibrahim D M Khalil T Mostafa A A | 1999 | Ceramics International1999，25，3： | 1 |
| 9 | Development and validation of a one-step immunoassay determination of Cadmium in human serum显示文摘 | Darwish Ibrahim A Blake D A | 2002 | Analytical Chemistry2002，74，1： | 1 |
| 10 | Early versus late enteral feeding of mechanically ventilated patients:results of a clinical trial显示文摘 | IBRAHIM E H MEHRINGER L PRENTICE D | 2002 | J Parenter Enteral Nutr2002，26，3： | 1 |
| 11 | Traveling- wave -based fault- location scheme for multiend- aged underground cable system显示文摘 | GILANY M G IBRAHIM D K SAYED E | 2007 | IEEE Transactions on Power Delivery2007，22，1： | 1 |
| 12 | m - Learning : An experiment in using SMS to support learning new English language words 显示文摘 | Cavus N & Ibrahim D | 2009 | British Journal Of Education Technology2009，，40： | 1 |
| 13 | Microccontroller based applied digital control显示文摘 | Ibrahim D | 2006 | Washington Wiley Online Library2006，，1： | 1 |
| 14 | Submucosal injection of the silver-human albumin complex for the treatment of bronchopleural fistula 显示文摘 | Andreetti C D' Andrilli A Ibrahim M | 2010 | Eur J Cardiothorae Surg2010，37，1： | 1 |
| 15 | Traveling-wave-based fault-location scheme for multiend-aged underground cable system 显示文摘 | GILANY M IBRAHIM D K ELDIN E T | 2007 | IEEE Transactions on Power Delivery2007，22，1： | 1 |
| 16 | Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab,paclitaxel,and epirubicin chemotherapy:results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancer显示文摘 | Buzdar A Ibrahim N Francis D | 2005 | J Clin Oncol2005，23，16： | 1 |
| 17 | mtDNA phylo geography and postglacial patterns of subdivision in the meadow grasshopper Chorthippus parallelus显示文摘 | Lunt D H Ibrahim K M Hewitt G M | 1998 | He redity1998，80，： | 1 |
| 18 | Intrapleural intercostal nerve block associated with mini-thoracotomy improves pain control after major lung resection 显示文摘 | D'Andrilli A Ibrahim M Ciccone A M | 2006 | Eur J Cardiothorac Surg2006，29，5： | 1 |
| 19 | Microbial production of surfactants and their commercial potential显示文摘 | JITENDRA D D IBRAHIM M B | 1997 | Microbiology and Molecular Bi- ology Reviews1997，61，1： | 1 |
| 20 | Analytical and experimental investigations of disc brake noise using the frequency - time domain 显示文摘 | Beloiu D M Ibrahim R A | 2006 | Structural Control and Health Monitoring2006，13，1： | 1 |
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