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| 1 | Circulating nitric oxide is suppressed in obstructive sleep apnea and is reversed by nasal continuous positive airway pressure显示文摘 | Ip M S Lam B Chan L Y | 2000 | Am J Respir Crit Care Med2000，162，6： | 2 |
| 2 | Risk stratification in symptomatic intracranial atherosclerotic disease with conventional vascular risk factors and cerebral haemodynamics显示文摘Background and purpose Symptomatic intracranial atherosclerotic stenosis(sICAS)is associated with a considerable risk of recurrent stroke despite contemporarily optimal medical treatment.Severity of luminal stenosis in sICAS and its haemodynamic significance quantified with computational fluid dynamics(CFD)models were associated with the risk of stroke recurrence.We aimed to develop and compare stroke risk prediction nomograms in sICAS,based on vascular risk factors and these metrics.Methods Patients with 50%-99%sICAS confirmed in CT angiography(CTA)were enrolled.Conventional vascular risk factors were collected.Severity of luminal stenosis in sICAS was dichotomised as moderate(50%-69%)and severe(70%-99%).Translesional pressure ratio(PR)and wall shear stress ratio(WSSR)were quantified via CTA-based CFD modelling;the haemodynamic status of sICAS was classified as normal(normal PR&WSSR),intermediate(otherwise)and abnormal(abnormal PR&WSSR).All patients received guideline-recommended medical treatment.We developed and compared performance of nomograms composed of these variables and independent predictors identified in multivariate logistic regression,in predicting the primary outcome,recurrent ischaemic stroke in the same territory(SIT)within 1 year.Results Among 245 sICAS patients,20(8.2%)had SIT.The D2H2A nomogram,incorporating diabetes,dyslipidaemia,haemodynamic status of sICAS,hypertension and age≥50 years,showed good calibration(P for Hosmer-Lemeshow test=0.560)and discrimination(C-statistic 0.73,95%CI 0.60 to 0.85).It also had better performance in risk reclassification and provided larger net benefits in decision curve analysis,compared with nomograms composed of conventional vascular risk factors only,and plus the severity of luminal stenosis in sICAS.Sensitivity analysis in patients with anterior-circulation sICAS showed similar results.Conclusions The D2H2A nomogram,incorporating conventional vascular risk factors and the haemodynamic significance of sICAS as assessed in CFD models,could be a useful tool to stratify sICAS patients for the risk of recurrent stroke under contemporarily optimal medical treatment. | Xuan Tian Hui Fang Linfang Lan Hing Lung Ip Jill Abrigo Haipeng Liu Lina Zheng Florence S Y Fan Sze Ho Ma Bonaventure Ip Bo Song Yuming Xu Jingwei Li Bing Zhang Yun Xu Yannie O Y Soo Vincent Mok Ka Sing Wong Thomas W Leung Xinyi Leng | 2023 | Stroke & Vascular Neurology2023，8，1： | 2 |
| 3 | Discriminative wavelet shape descriptors for recognition of 2-D patterns 显示文摘 | Shen D Ip Horace H S | 1999 | Pattern Recognition1999，32，2： | 2 |
| 4 | Recent progress in processing and properties of ZnO显示文摘 | Pearton S J Norton D P Ip K | 2005 | Prog Mater Sci2005，50，： | 1 |
| 5 | Wettability of Nickel Coated Graphite by Aluminum显示文摘 | Ip S W Sridhar R Toguri J M | 1998 | Materials Science and Engineering A1998，244，： | 1 |
| 6 | An evidence-based review of important issues concerning neonatal hyperbilirubinemia显示文摘 | Ip S Chung M Kulig J O'Brien Sege R Glicken S | 2004 | Pediatrics2004，114，1： | 1 |
| 7 | Hu- man papillomavirus testing and conventional pap smear cytology as optional screening tools of women at different risk for cervical cancer in the countries of the former soviet union显示文摘 | Syrjanen S Shabalova IP Petroviehev N | 2002 | J Low Gcnit Tract Dis2002，6，2： | 1 |
| 8 | Human papillomavirus testing and conventional pap smear cytology as optional screening tools of women at different risks for cervical Cancer in the countries of the former Soviet union 显示文摘 | Syrjanen S Shabalova IP Petrovichev N | 2002 | J Low Genit Tract Dis2002，6，2： | 1 |
| 9 | Discriminative wavelet shape descrip- tors for recognition of 2-D patterns 显示文摘 | SHEN D IP H H S | 1999 | Pattern Recogni- tion1999，32，2： | 1 |
| 10 | Strain-dependent dysregulation of one-carbon metabolism in male mice is associated with choline-and folate-deficient diet-induced liver injury 显示文摘 | Pogribny IP Kutanzi K Melnyk S | 2013 | FASEB J2013，27，6： | 1 |
| 11 | Intercontinental Spread of Asian-Origin H5N8to North America through Beringia by Migratory Birds显示文摘 | Lee D H Torchetti M K Winker K Ip H S Song C S Swayne D E | 2015 | J Virol2015，89，12： | 1 |
| 12 | Retinotopic or- ganization in children measured with fMRI 显示文摘 | Conner IP Shanna S Lemieux SK Mendola JD | 2004 | J Vis2004，4，6： | 1 |
| 13 | High-performance liquid chromatographic method for the simuhanous detection of the adulteration of cereal flours with melamine and relatedtriazine by-products ammeline,ammelide, and cyanuric acid显示文摘 | EHLING S TEFERA S HO IP | 2007 | Food Additives and Contaminants2007，24，12： | 1 |
| 14 | Human papillomavir us testing and conventional Pap smear cyto-logy as optional screening tols of women at different risksfor cervical cancer in countries of the former so viet union显示文摘 | Syrjanen S Shaba Iova IP Petrovichev N | 2002 | J Low Genit Tract Dis2002，6，2： | 1 |
| 15 | Nanotherapy for posterior eye diseases 显示文摘 | Kaur IP Kakkar S | 2014 | J Controlled Release2014，193，： | 1 |
| 16 | Prospective comparison of three predictive rules for assessing severity of community-acquired pneumonia in Hong Kong显示文摘 | Yan Man S Lee N Ip M | 2007 | Thorax2007，62，4： | 1 |
| 17 | Phosphati-dylinositol 3-kinase is a Central Mediator of NMDA Receptor Signaling to MAP Kinase (Erk1/2),Akt/PKB and CREB in Stristal Neurons显示文摘 | PERKINTON M S IP J K WOOD G L | 2002 | J Neurochem2002，80，2： | 1 |
| 18 | Are prorocentroid dimoflagellates monophyletic? A study of 25 species based on nuclear and mitochonodrial genes显示文摘 | Murray S Ip C L C Moore R | 2009 | Protist2009，160，： | 1 |
| 19 | Complement- mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma显示文摘 | Lajoie S Lewkowich IP Suzuki Y | 2010 | Nat Immunol2010，11，10： | 1 |
| 20 | Human papillo- mavims testing and conventional Pap smear cytology as optional screening tools of women at different risks for cervical cancer in the Countries of the former Soviet Union 显示文摘 | Syrjanen S Shabalova IP Petrovichev N | 2002 | J Low Genit Tract Dis2002，6，2： | 1 |
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