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| 1 | Portable lensless wide-field microscopy imaging platform based on digital inline holography and multi-frame pixel super-resolution显示文摘In this paper,an irregular displacement-based lensless wide-field microscopy imaging platform is presented by combining digital in-line holography and computational pixel super-resolution using multi-frame processing.The samples are illuminated by a nearly coherent illumination system,where the hologram shadows are projected into a complementary metal-oxide semiconductor-based imaging sensor.To increase the resolution,a multi-frame pixel resolution approach is employed to produce a single holographic image from multiple frame observations of the scene,with small planar displacements.Displacements are resolved by a hybrid approach:(i)alignment of the LR images by a fast feature-based registration method,and(ii)fine adjustment of the sub-pixel information using a continuous optimization approach designed to find the global optimum solution.Numerical method for phase-retrieval is applied to decode the signal and reconstruct the morphological details of the analyzed sample.The presented approach was evaluated with various biological samples including sperm and platelets,whose dimensions are in the order of a few microns.The obtained results demonstrate a spatial resolution of 1.55 μm on a field-of-view of<30 mm^(2). | Antonio C Sobieranski Fatih Inci H Cumhur Tekin Mehmet Yuksekkaya Eros Comunello Daniel Cobra Aldo von Wangenheim Utkan Demirci | 2015 | Light(Science & Applications)2015，4，1： | 7 |
| 2 | Effectivity of intraoperative adjustable suture technique in horizontal strabismus显示文摘AIM:To compare the long-term effectivity of intraoperative adjustable suture technique with traditional non-adjustable strabismus surgery.·METHODS:Two hundred and thirty-three patients,who underwent strabismus surgery either with traditional procedures or one-stage intraoperative adjustable suture technique,were included in our long-term follow-up study.One hundred and eighteen patients were evaluated in traditional surgery group(TSG) and 115 who underwent adjustable suture were in the one-stage intraoperative adjustable surgery group(ASG).In this group 9 patients had paralytic strabismus and 16 had reoperations,2 patients had restrictive strabismus related to thyroid eye disease.The mean follow up in the TSG was 26.2 months and it was 24.8 months in the ASG group.·RESULTS:In patients with exotropia(XT) the mean correction of deviation for near fixation in ASG(32.4 ±13.2PD) and in TSG(26.4±8.2PD) were similar(P =0.112).The correction for distant fixation in ASG(33.2±11.4PD)and TSG(30.9±7.2PD) were not significantly different(P =0.321).In patients with esotropia(ET) even the mean correction of deviation for both near(31 ±12PD) and distant(30.6±12.8PD) fixations were higher in ASG thanin TSG,for both near(28.27±14.2PD) and distant(28.9±12.9PD) fixations,the differences were not significant(P =0.346,0.824 respectively).The overall success rate of XT patient was 78.9% in TSG and 78.78% in ASG,the difference was not significant(P =0.629).The success rates were 78.75% in TSG and 75.51% in ASG in ET patient,which was also not significantly different(P =0.821).·CONCLUSION:Although patients in ASG had more complex deviation such as paralysis,reoperations and restrictive strabismus,success rates of this tecnique was as high as TSG which did not contain complicated deviation.One-stage intraoperative adjustable suture technique is a safe and effective method for cooperative patient who has complex deviation. | Ayse Gul Kocak Altintas Hasan Basri Arifoglu Inci Kocak Midillioglu Elif Damar Gungor Saban Simsek | 2013 | International Journal of Ophthalmology(English edition)2013，6，4： | 3 |
| 3 | Urine products of bone breakdown as markers of bone resorption and clinical usefulness of urinary hydroxyproline:an overview显示文摘Purpose The purpose of this study is to review the urine products of bone breakdown as markers of bone resorption and usefulness of urinary hydroxyproline. Data Related researches published in 1985 -2000 were systematically reviewed. Results Bone markers could be used for early diagnosis of bone metabolic diseases. Biochemical markers of bone resorption that reflect osteoclast activity and/or collagen degradation provide a new and potentially important clinical tool for the assessment and monitoring of bone metabolism. Assessment of bone resorption can be achieved with measurement of urinary hydroxylysine glycosides, urinary excretion of the collagen pyridinium cross-links, urinary excretion of type I collagen telopeptide breakdown products (cross-linked telopeptides) and urinary hydroxyproline. Conclusion Urinary hydroxyproline has been in use as a marker of bone resorption, but it lacks sensitivity and specificity. It is a modified aminoacid that is a metabolic product of collagen breakdown.Hydroxyproline may be released either free or with fragments of the collagen molecule attached during bone resorption, and it is also liberated by the breakdown of complement and nonskeletal collagen. | Baris Simsek zgülKaracaer inci Karaca | 2004 | Chinese Medical Journal2004，17，2： | 3 |
| 4 | Comparison of multichannel intraluminal impedance-pH monitoring and reflux scintigraphy in pediatric patients with suspected gastroesophageal reflux显示文摘AIM To evaluate the agreement of multichannel intraluminal impedance-p H monitoring(MII-p HM) and gastroesophageal reflux scintigraphy(GES) for the diagnosis of gastroesophageal reflux disease. METHODS Seventy-five consecutive patients with suspectedgastroesophageal reflux disease(GERD) underwent 24-h combined MII-p HM recording and one hour radionuclide scintigraphy during the course of the MIIpH M study. Catheters with 6 impedance channels and 1 p H sensor were placed transnasally. Impedance and p H data analysis were performed automatically and manually. For impedance monitoring, reflux was defined as a retrograde 50% drop in impedance, starting distally and propagating retrogradely to at least the next two more proximal measuring channels. Reflux index(RI, percentage of the entire record that esophageal p H is < 4.0) greater than 4.2% for p HM and number of refluxes more than 50 for 24 h for MII were accepted as positive test results. At scintigraphy, 240 frames of 15 seconds duration were acquired in the supine position. Gastroesophageal reflux was defined as at least one reflux episode in the esophagus. After scintigraphic evaluation, impedance-pH recordings and scintigraphic images were evaluated together and agreement between tests were evaluated with Cohen's kappa.RESULTS Sufficient data was obtained from 60(80%) patients(34 male, 56.7%) with a mean age of 8.7 ± 3.7 years(range: 2.5-17.3 years; median: 8.5 years). Chronic cough, nausea, regurgitation and vomiting were the most frequent symptoms. The mean time for recording of MII-pH M was 22.8 ± 2.4 h(range: 16-30 h; median: 22.7 h). At least one test was positive in 57(95%) patients. According to diagnostic criteria, GERD was diagnosed in 34(57.7%), 44(73.3%), 47(78.3%) and 51(85%) patients by means of p HM, MII, GES and MII-p HM, respectively. The observed percentage agreements/κ values for GES and p HM, GES and MII, GES and MII-p HM, and MII and p HM are 48.3%/-0.118; 61.7%/-0.042; 73.3%/0.116 and 60%/0.147, respectively. There was no or slight agreement between GES and p HM alone, MII alone or MII-p HM. p H monitoring alone missed 17 patients compared to combined MII-p HM. The addition of MII to pH monitoring increased the diagnosis rate by 50%.CONCLUSION No or slight agreement was found among p H monitoring, MII monitoring, MII-pH monitoring and GES for the diagnosis of gastroesophageal reflux disease. | Nuray Uslu Kizilkan Murat Fani Bozkurt Inci Nur Saltik Temizel Hülya Demir Aysel Yüce Biray Caner Hasan Ozen | 2016 | World Journal of Gastroenterology2016，22，43： | 2 |
| 5 | Effect of 1%brinzolamide and 0.5%timolol fixed combination on intraocular pressure after cataract surgery with phacoemulsification显示文摘AIM:To evaluate the effect of brinzolamide-timolol fixed combination on intraocular pressure(IOP)after cataract surgery.METHODS:The study included 92 eyes of 87 patients who underwent cataract surgery and intraocular lens implantation.Patients scheduled for phacoemulsification were assigned to 1 of 2 groups.The treatment group received 1 drop of brinzolamide-timolol fixed combination immediately after surgery,and the control group received no treatment.The IOP was measured preoperatively and at 2h and 24h postoperatively.RESULTS:The mean IOP change was lower in the treatment group than in the control group at 2h postoperatively.The difference between the mean IOP values of the two groups at 2h postoperatively was found to be statistically significant.Twenty-four hours after the surgery,the mean IOP change was still higher in the control group when compared to the treatment group.CONCLUSION:The fixed combination brinzolamidetimolol can effectively reduce IOP after cataract surgery. | Kemal rnek Nesrin Byktortop Nurgl rnek Reyhan Ogurel Inci Elif Erbahceci Zafer Onaran | 2013 | International Journal of Ophthalmology(English edition)2013，6，6： | 2 |
| 6 | Phase II, open-label, randomized study (SIGN) of single-agent gefitinib (IRESSA) or docetaxel as second-line therapy in patients with advanced (stage IIIb or IV) non-small-cell lung cancer显示文摘 | Tanja Cufer Eduard Vrdoljak Rabab Gaafar Inci Erensoy Kristine Pemberton | 2006 | Anti-Cancer Drugs2006，，4： | 2 |
| 7 | 化疗所致恶心呕吐对复发性卵巢癌患者预后的影响:纳入1213例患者数据的meta分析结果显示文摘背景与目的 本研究旨在研究化疗所致恶心呕吐(chemotherapy-induced nausea and vomiting,CINV)对化疗药物剂量减少、中止以及患者生存获益的潜在影响。方法 本研究基于德国东北妇科肿瘤学会(North-Eastern German Society of Gynecological Oncology,NOGGO)开展的3项Ⅱ/Ⅲ期临床试验中的1213例复发性卵巢癌患者的原始数据,进行了个体病例数据的meta分析。通过Logistic回归和Cox回归分析,对年龄、ECOG评分、化疗周期数、复发次数、并发症以及不同研究等因素进行校正后,评估相应的比值比和风险比(hazard ratio,HR)。结果 大多数(58.1%)患者发生了恶心,且近三分之一(31.0%)的患者出现呕吐。CINV的发生与FIGO分期、分级、组织学以及复发次数无关;必须的化疗药物减量和中止化疗与恶心、呕吐的发生亦无相关性(P=0.88,P=0.39;P=0.25,P=0.54)。发生Ⅲ/Ⅳ级恶心呕吐患者的无进展生存期更短(P=0.02,Ⅲ/Ⅳ级恶心的HR=1.58,95%CI:1.14–2.20;P=0.02,Ⅲ/Ⅳ级呕吐的HR=1.67,95%CI:1.15–2.42)。发生Ⅲ/Ⅳ级恶心和呕吐的患者生存期较短(P <0.001,Ⅲ/Ⅳ级恶心的HR=2.35,95%CI:1.64–3.37;P <0.001,Ⅲ/Ⅳ级呕吐的HR=1.67,95%CI:1.15–2.42)。结论 CINV与复发性卵巢癌患者较差的预后显著相关,而与必须的化疗药物减量和中止无相关性。本研究强调CINV防治是早期最佳支持治疗的重要环节。 | Hannah Woopen R Richter R Chekerov G Inci S Alavi J P Grabowski J Sehouli 尹如铁(译) | 2022 | 癌症2022，41，6： | 2 |
| 8 | Effect of raloxifene on cerebral vasospasm following experimental subarachnoid hemorrhage in rats 显示文摘 | Gulsen S Inci S Yuruk S | 2007 | Neurol Med Chir (Tokyo)2007，47，12： | 1 |
| 9 | Pulmonary embolism in neurosurgical patients显示文摘 | Inci S Erbengi A Berker M | 1995 | Surg Neurol1995，43，2： | 1 |
| 10 | Spinal dural arteriovenous fistula andvenous aneurysm:an unusual ssociation显示文摘 | Inci S Akdemir P Ozgen T | 2003 | Surg Neurol2003，60，4： | 1 |
| 11 | Reference equations for ultrasound bone densitometry of the radius in Central European children and adolescents显示文摘 | Scherrer MJ Rochat MK Inci D | 2014 | Osteoporosis international2014，25，11： | 1 |
| 12 | Bilateral middle cerebral artery aneurysms: a comparative st!dy of unilateral and bilateral approaches 显示文摘 | Inci S Akbay A Ozgen T | 2012 | Neurosurg Rev2012，35，： | 1 |
| 13 | The relationship between epicardial fat thickness and gestational diabetes mellitus显示文摘 | Nar G Inci S Aksan G | 2014 | Diabetol Metab Syndr2014，6，1： | 1 |
| 14 | Treatment of chronic spinal cord iniured patients with autologous bone marrow-derived hematopoietic stem cell transplantation: 1-year follow-up显示文摘 | Deda H Inci M C Kurekci A E | 2008 | Cytotherapy2008，10，6： | 1 |
| 15 | Expression of protease-activated- receptor 2 (PAR-2) in human esophageal mucosa显示文摘 | Inci K Edebo A Olbe L | 2009 | Scand J Gastroenterol2009，44，6： | 1 |
| 16 | An integrated model of downtown parking and traffic congestion 显示文摘 | ARNOTT R INCI E | 2006 | Journal of Urban Economics2006，60，3： | 1 |
| 17 | Intrapleural fibrinolytic treatment of traumatic clotted hemothorax 显示文摘 | Inci I Ozcelik C Uiku R | 1998 | Chest1998，114，1： | 1 |
| 18 | In- trapleural fibrinolytic treatment of trau- matic clotted hemothorax显示文摘 | Inci I Ozcelik C Ulku R | 1998 | Chest1998，114，1： | 1 |
| 19 | Thoraeoscopic lobec- tomy for benign disease-a single centre study on 64 cases 显示文摘 | Weber A Stammberger U Inci I | 2001 | Eur J Cardiothorac Surg2001，20，3： | 1 |
| 20 | Intracranial aneurysms and arterial hypertension:a review and hypothesis显示文摘 | Inci S Spetzler RF | 2000 | Surg Neurol2000，53，6： | 1 |
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