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| 1 | Effect of infant formula on stool characteristics of young infants 显示文摘 | Hyams JS Treem WR Etienne NL | 1995 | Pediatrics1995，95，1： | 1 |
| 2 | Dyspepsia in chil- dren and adolescents: a prospective study显示文摘 | Hyams JS Davis P Sylvester FA | 2000 | J Pediatr Gas- troenterol Nutr2000，30，4： | 1 |
| 3 | Recent advances in diagnosis and treatment of gastrointestinal hemorrhage in infants and children显示文摘 | Hyams JS Leiehtner AM Schwartz AN | 1985 | J Pediatries1985，106，1： | 1 |
| 4 | Dyspepsia in children and Moles - cents: a prospective study 显示文摘 | Hyams JS Davis P Sylvester FA | 2000 | Pediatr Gastroenterel Nutr2000，30，4： | 1 |
| 5 | Dyspepsia in children and adolescents:aprospective study显示文摘 | Hyams JS,Davis P,Sylvester FA | 2000 | J Pediatr Gastroenterol Nutr2000，30，4： | 1 |
| 6 | Abdominal pain and irritable bowel syndrome in adolescents:a community-based study显示文摘 | Burke G Davis PM | 1996 | J Pediatr1996，129，2： | 1 |
| 7 | Abdominal pain and irritable bowel syndrome in adolescents: a community-based study显示文摘 | Hyams JS Burke G Davis PM | 1996 | J Pediatr1996，129，： | 1 |
| 8 | Suppression of gastric acid secretion by intravenous administration of famotidine in children显示文摘 | Treem WR Davis PM Hyams JS | 1991 | J Pediatr1991，118，5： | 1 |
| 9 | Abdominal pain and irritable bowel syndrome in adolescents:a communitybased study显示文摘 | Hyams JS Burke G Davis PM | 1996 | J Pediatr1996，129，2： | 1 |
| 10 | Childhood functional gastrointestinal disorders 显示文摘 | Rasquin-Weber A Hyman PE Cucchiara S Fleisher DR Hyams JS Milla PJ | 1999 | Gut1999，2，： | 1 |
| 11 | Dyspepsia in children and adolescents; A prospective study 显示文摘 | Hyams JS Davis P Sylvester FA | 2000 | J Pediatr Gastroenterol Nutr2000，30，4： | 1 |
| 12 | Abdominal pain and irritable bowel syndrome in adolescents:a community-based study显示文摘 | Hyams JS Burke G Davis DM | 1996 | Pediatr1996，129，： | 1 |
| 13 | Dyspepsia in children and adolescents:a prospective study显示文摘 | Hyams JS Davis P Sylvester FA | 2000 | J Pediatr Gastroenterol Nutr2000，30，4： | 1 |
| 14 | Dyspepsia in children and adolescents: a prospective study 显示文摘 | Hyams JS Davis P Sylvester FA | 2000 | J Pediatr Gastroenterol Nutr2000，30，： | 1 |
| 15 | Alterations in bone metabolism in children with inflam- matory bowel disease, an in vitro study 显示文摘 | Hyams JS | 1997 | J Pediatr Gastroen- terol Nutr1997，24，3： | 1 |
| 16 | Recurrent abdominal pain and the bio- psychosocial model of medical praetice显示文摘 | Hyams JS Hyman PE | 1998 | J Pediatr1998，133，4： | 1 |
| 17 | Development and validation of a Pediatric Crohn's Disease Activty Index显示文摘 | Hyams JS Ferry GD Mandel FS | 1991 | J Pediat Gastroen-terol Nutr1991，12，4： | 1 |
| 18 | Childhood functional gastrointestinal disorders: child/adolescent 显示文摘 | Rasquin A Di Lorenzo C Forbes D Guiraldes E Hyams JS Staiano A | 2006 | Gastroenterology2006，130，5： | 1 |
| 19 | Recurrent Abdominal Pain in Children 显示文摘 | Zeiter DK Hyams JS | 2002 | Pediatr Clin North Am2002，49，1： | 1 |
| 20 | Assessing disease activity using the pediatric Crohn’s disease activity index:Can we use subjective or objective parameters alone?显示文摘BACKGROUND The pediatric Crohn’s disease activity index(PCDAI)is used as a standard tool to assess disease activity in clinical trials for pediatric Crohn’s disease.AIM To examine which items on the PCDAI drive assessment of disease activity,and how subgroups of subjective and objective items reflect change in disease state over time.METHODS Selective raw data from three prospectively collected datasets were combined,including 703 children with full PCDAI data at baseline,at 3-mo(Q1,n=670),and 1-year(Q4,n=474).Change in individual PCDAI scores from baseline to Q1 and to Q4 were examined using the non-weighted PCDAI.RESULTS Abdominal pain,well-being,weight,and stooling had the highest change scores over time.Objective indicators including albumin,abdominal exam,and height velocity followed.Change scores for well-being and abdominal exam did not explain significant variance at Q1 but were significant predictors at Q4(P<0.001 and P<0.05).Subjective and objective subgroups of items predicted less variance(18%and 22%)on total PCDAI scores at Q1 and Q4 compared to the full PCDAI,or a composite scale(both 32%)containing significant predictors.CONCLUSION Although subjective items on the PCDAI change the most over time,the full PCDAI or a smaller composite of items including a combination of subjective and objective components classifies disease activity better than a subgroup of either subjective or objective items alone.Reliance on subjective or objective items as stand-alone proxies for disease activity measurement could result in misclassification of disease state. | Amy Grant Trudy Lerer Anne M Griffiths JS Hyams Anthony Otley | 2021 | World Journal of Gastroenterology2021，27，30： | 1 |
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