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| 1 | Consensus statement on the epidemiology,diagnosis,prevention,and management of cow's milk protein allergy in the Middle East:a modified Delphi-based study显示文摘Background This study aimed to develop an expert consensus regarding the epidemiology,diagnosis,and management of cow’s milk protein allergy(CMPA)in the Middle East.Methods A three-step modified Delphi method was utilized to develop the consensus.Fifteen specialized pediatricians participated in the development of this consensus.Each statement was considered a consensus if it achieved an agreement level of>80%.Results The experts agreed that the double-blind placebo-controlled oral challenge test(OCT)should be performed for 2-A weeks using an amino acid formula(AAF)in formula-fed infants or children with suspected CMPA.Formula-fed infants with confirmed CMPA should be offered a therapeutic formula.The panel stated that an extensively hydrolyzed formula(eHF)is indicated in the absence of red flag signs.At the same time,the AAF is offered for infants with red flag signs,such as severe anaphylactic reactions.The panel agreed that infants on an eHF with resolved symptoms within 2-4 weeks should continue the eHF with particular attention to the growth and nutritional status.On the other hand,an AAF should be considered for infants with persistent symptoms;the AAF should be continued if the symptoms resolve within 2-4 weeks,with particular attention to the growth and nutritional status.In cases with no symptomatic improvements after the introduction of an AAF.other measures should be followed.The panel developed a management algorithm,which achieved an agreement level of 90.9%.Conclusion This consensus document combined the best available evidence and clinical experience to optimize the management of CMPA in the Middle East. | Moustafa A.El-Hodhod Mortada H.F.El-Shabrawi Ahmed AIBadi Ahmed Hussein AM Almehaidib Basil Nasrallah Ebtsam Mohammed AIBassam Hala El Feghali Hasan M.Isa Khaled Al Saraf Maroun Sokhn Mehdi Adeli Najwa Mohammed Mousa Al-Sawi Pierre Hage Suleiman Al-Hammadi | 2021 | World Journal of Pediatrics2021，17，6： | 3 |
| 2 | Effect of chronic excess iodine intake on thyroid function and oxidative stress in hypothyroid rats显示文摘 | Hussein AA Abbas AM El Wakil GA | 2012 | Can J Physiol Pharmacol2012，90，5： | 1 |
| 3 | Alterations of the CD4(+), CD8 (+) T cell subsets,interleukins-1beta,IL-10,IL-17,tumor necrosis factor-alpha and soluble intercellular adhesion molecule-1 in rheumatoid arthritis and osteoarthritis: preliminary observations 显示文摘 | Hussein MR Fathi NA El-Din AM | 2008 | Pathol Oncol Res2008，14，3： | 1 |
| 4 | Management of neovascu- lar glaucoma with panretinal photocoagulation,intravitreal beva- cizumab,and subsequent trabeculectomy with mitomycin C 显示文摘 | Alkawas AA Shahien EA Hussein AM | 2010 | J Glaucoma2010，19，9： | 1 |
| 5 | Tumor lysis syndrome after induction chemotherapy in small-cell lung carcinoma显示文摘 | Feun LG | 1990 | Am J Clin Oncol1990，13，1： | 1 |
| 6 | Protection against chem- otherapy-induced alopecia By cyclosporine A in the newborn rat animal model显示文摘 | Hussein AM Stuart A Peters WP | 1995 | Dermatology1995，190，3： | 1 |
| 7 | Molecular basis of β -thalassemia in the western province of Saudi Arabia: i- dentification of rare β - thalassemia mutations 显示文摘 | Abuzenadah AM Hussein IM Damanhouri GA | 2011 | Hemoglobin2011，35，4： | 1 |
| 8 | Effect of dehydroepiandros- terone (dhea) on memory and brain derived neurotrophic factor (bdnf) in a rat model of vascular dementia 显示文摘 | Sakr HF Khalil KI Hussein AM | 2014 | J Physiol Pharma- col2014，65，1： | 1 |
| 9 | Alterations of the CD4(+),CD8 (+) T cell subsets,interleukins-1beta,IL-10,IL-17,tumor necrosis factor-alpha and soluble intercellular adhesion molecule-1 in rheumatoid arthritis and osteoarthritis:preliminary observations显示文摘 | Hussein MR Fathi NA El-Din AM | 2008 | Pathol Oncol Res2008，14，3： | 1 |
| 10 | Protection from chemotherapy induced alopecia in a rat model 显示文摘 | Hussein AM Jimenez JJ McCall CA | 1990 | Science1990，249，： | 1 |
| 11 | Evaluation of an innovative computer-assisted sagittal split ramus osteotomy to reduce neurosensory alterations following orthognathic sur- gery: apilot study 显示文摘 | Al-Ahmad HT M Saleh MW Hussein AM | 2013 | Int J Med Robot2013，9，2： | 1 |
| 12 | Pathophysiolog- ical variability of different genotypes of human Blastocystis hominis Egyptian isolates in experimentally infected rats 显示文摘 | Hussein EM Hussein AM Eida MM | 2008 | Parasitol Res2008，102，5： | 1 |
| 13 | Palhoplaysiological variability of differert genotypes of human Bltatocystis hominis Egyptian isolates in experimentally infected rats 显示文摘 | Hussein EM Hussein AM Eida MM et td | 2008 | Parasilol Res2008，102，5： | 1 |
| 14 | Management of neovas-cular glaucoma with panretinal photocoagulation, intravitreal bev- acizumab, and subsequent trabeculectomy with mitomycin C 显示文摘 | Alkawas AA Shahien EA Hussein AM | 2010 | J Glaucoma2010，19，9： | 1 |
| 15 | Pigment ep- ithelium-derived factor inhibits retinal microvaseular dysfunction induced by 12/15 -lipoxygenase -derived eieosanoids显示文摘 | Ibrahim AS Tawfik AM Hussein KA | 2015 | Biochim Biophys Acta2015，1851，3： | 1 |
| 16 | Disappointing long- term outcomes after stapled transanal rectal resection for obstructed defecation 显示文摘 | Madbouly KM Abbas KS Hussein AM | 2010 | World J Surg2010，34，9： | 1 |
| 17 | Orbital steroid injection versus oral steroid therapy in management of thyroid- related ophthalmopathy 显示文摘 | Alkawas AA Hussein AM Shahien EA | 2010 | Clin Experiment Ophthalmol2010，38，7： | 1 |
| 18 | Metastatic lymph node ra-tio in stage III rectal carcinoma is a valuable prognostic factoreven with less than 12 lymph nodes retrieved: a prospective study显示文摘 | Madbouly KM Abbas KS Hussein AM | 2014 | Am J Surg2014，207，6： | 1 |
| 19 | Protection against chemotherapy-induced alopecia by cyclosporin A in the newborn rat animal model显示文摘 | Hussein AM Stuart A Peters WP | 1995 | Dermatology1995，190，3： | 1 |
| 20 | Effect of dehydro- epiandrosterone (DHEA) on memory and brain derived neu- rotrophic factor(BDNF) in a rat model of vascular dementia 显示文摘 | Sakr HF Khalil KI Hussein AM | 2014 | J Physiol Pharmacol2014，65，1： | 1 |
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