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| 1 | Diagnostic accuracy of tests for Helicobacter pylori in an Alaska Native population显示文摘AIM:To evaluate the accuracy of two non-invasivetests in a population of Alaska Native persons. Highrates of Helico bacter pylori(H. pylori) infection,H. pylori treatment failure,and gastric cancer in this population necessitate documentation of infection status atmultiple time points over a patient's life.METHODS:In 280 patients undergoing endoscopy,H. pylori was diagnosed by culture,histology,rapidurease test,13C urea breath test(UBT) ,and immuno-globulin G antibodies to H. pylori in serum. The performances of 13C-UBT and antibody test were compared to a gold standard defined by a positive H. pylori testby culture or,in case of a negative culture result,bypositive histology and a positive rapid urease test.RESULTS:The sensitivity and specificity of the 13C-UBT were 93% and 88%,respectively,relative to thegold standard. The antibody test had an equivalents ensitivity of 93% with a reduced specificity of 68%.The false positive results for the antibody test were as-sociated with previous treatment for an H. pylori infection [relative risk(RR) = 2.8]. High levels of antibodiesto H. pylori were associated with chronic gastritis and male gender,while high scores in the 13C-UBT testwere associated with older age and with the H. pyloribacteria load on histological examination(RR = 4.4) .CONCLUSION:The 13C-UBT out performed the anti-body test for H. pylori and could be used when a non-invasive test is clinically necessary to document treatment out come or when monitoring for reinfection. | Dana L Bruden Michael G Bruce Karen M Miernyk Julie Morris Debby Hurlburt Thomas W Hennessy Helen Peters Frank Sacco Alan J Parkinson Brian J McMahon | 2011 | World Journal of Gastroenterology2011，17，42： | 3 |
| 2 | A human homologue of the Drosophila Toll protein signals activation of adaptive immunity显示文摘 | Medzhitov R Preston- Hurlburt P Janeway CA | | 0，，： | 2 |
| 3 | Femoral nerve block improves analgesia outcomes after total knee arthroplasty:a meta-analysis of randomized controlled trials显示文摘 | Paul JE Arya A Hurlburt L | 2010 | Anesthesiology2010，113，5： | 1 |
| 4 | Direct ultrasound measurement of longitudinal, circumferential, and radial strain using 2-dimensional strain imaging in normal adults 显示文摘 | Hurlburt HM Aurigemma GP Hill JC | 2007 | Eehoeardiography2007，24，7： | 1 |
| 5 | MyD88 is an adaptor protein in the hToll/IL - 1 receptor family signaling pathways显示文摘 | Medzhitov R Preston - Hurlburt P Kopp E | 1998 | Mol Cell1998，2，： | 1 |
| 6 | Prediction of the transition from stratified to slug and plug flow for long pipes显示文摘 | E.T. Hurlburt T.J. Hanratty | 2002 | International Journal of Multiphase Flow2002，，5： | 1 |
| 7 | Coupled dynamics of the South China Sea, Sulu Sea, and the Pacific Ocean 显示文摘 | Metzger E J Hurlburt H | 1996 | J Geophys Res1996，101，12： | 1 |
| 8 | The Internet of things: a reality check显示文摘 | HURLBURT G F VOAS J MILLER K W | 2012 | IT Professional2012，14，03： | 1 |
| 9 | Direct ultrasound measure- ment of longitudinal,circumferential,and radial strain using 2-dimen- sional strain imaging in normal adults显示文摘 | Hurlburt HM Aurigemma GP Hill JC | 2007 | Echocardiography2007，24，7： | 1 |
| 10 | Coupled dynamics of the South Chi- na Sea, the Sulu Sea, and the Pacific Ocean 显示文摘 | Metzger E J Hurlburt H E | 1996 | Journal of Geo- physical Research1996，101，12： | 1 |
| 11 | A human homologue of the Drosophila Toll protein signals activation of adaptive immunity 显示文摘 | PRESTON M HURLBURT P JANEWAY C A JR | 1997 | Nature1997，388，6640： | 1 |
| 12 | Ahuman honologue of the Drosophila Toll protein signals activation of adaptive immunity 显示文摘 | Medzhitov R Preston - Hurlburt P Janeway CA Jr | 1997 | Nature1997，388，5： | 1 |
| 13 | A human homologue of the D10 - sophila Toll protein signals activation of adaptive im- munity 显示文摘 | Medzhitov R Preston -Hurlburt P Janeway CAl | 1997 | Nature1997，388，： | 1 |
| 14 | Femoral nerve block improves analgesia outcomes after total knee ar- throplasty: ameta-analysis of randomized controlled trials 显示文摘 | Paul J E Arya A Hurlburt L | 2010 | Anesthesiology2010，113，5： | 1 |
| 15 | The importance of high horizontal resolution and accurate coastline geometry in modeling South China Sea inflow显示文摘 | METZGER E J HURLBURT H | 2001 | Geoph Res Lett2001，28，： | 1 |
| 16 | Femoral nerve block improves analgesia outcomes after total knee arthro- plasty: a meta-analysis of randomized controlled trials 显示文摘 | Paul J E Arya A Hurlburt L | 2010 | Anesthesiology2010，113，5： | 1 |
| 17 | The importance of high horizontal resolution and accurate coastline geometry in modeling South China Sea inflow显示文摘 | METZGER E J HURLBURT H | 2001 | Geophysical Research Letters2001，28，： | 1 |
| 18 | A human homologue of the Drosophila Toll protein signals activation of adaptor immunity 显示文摘 | Medzhitov R Preston - Hurlburt P Janeway CA Jr | 1997 | Nature1997，388，： | 1 |
| 19 | The nonconcept of species diversity and critique and alternative parameters显示文摘 | HURLBURT SH | | 0，，： | 1 |
| 20 | Navy Real-time Global Modeling Systems显示文摘 | Rhodes R C Hurlburt H E WallcraR A J | 2002 | Oceanography2002，15，： | 1 |
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