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| 1 | Management of adverse effects of Peg - IFN and ribavirin therapy for hepatitis C显示文摘 | Sulkowski M S Cooper C Hunyady B | 2011 | Nat Rev Gastroenterol Hepatol2011，8，4： | 1 |
| 2 | Strongyloides hyper-infection causing life-threatening gastrointestinal bleeding显示文摘A 55-year old male patient was diagnosed with strongy- loides hyper-infection with stool analysis and intestinal biopsy shortly after his chemotherapy for myeloma. He was commenced on albendazole anthelmintic therapy. After initiation of the treatment he suffered life- threatening gastrointestinal (GI) bleeding. Repeated endoscopies showed diffuse multi-focal intestinal bleeding. The patient required huge amounts of red blood cells and plasma transfusions and correction of haemostasis with recombinant activated factor Ⅶ. Abdominal aorto-angiography showed numerous micro- aneurysms (‘berry aneurysms’) in the superior and inferior mesenteric arteries’ territories. While the biopsy taken prior to the treatment with albendazole did not show evidence of vasculitis, the biopsy taken after initiation of therapy revealed leukoclastic aggregations around the vessels. These findings suggest that, in addition to direct destruction of the mucosa, vasculitis could be an important additive factor causing the massive GI bleeding during the anthelmintic treatment. This might result from substances released by the worms that have been killed with anthelmintic therapy. Current guidelines advise steroids to be tapered and stopped in case of systematic parasitic infections as they might reduce immunity and precipitate parasitic hyper-infection. In our opinion, steroid therapy might be of value in the management of strongyloides hyper- infection related vasculitis, in addition to the anthelmintic treatment. Indeed, steroid therapy of vasculitis with other means of supportive care resulted in cessation of the bleeding and recovery of the patient. | Lajos Csermely Hassan Jaafar Jorgen Kristensen Antonio Castella Waldemar Gorka Ahmed Ali Chebli Fawaz Trab Hussain Alizadeh Béla Hunyady | 2006 | World Journal of Gastroenterology2006，12，39： | 1 |
| 3 | In vitro anti-diabetic activity and chemical characterization of an apolar fraction of Morus alba leaf water extract 显示文摘 | Hunyadi A Veres K Danko B | 2013 | Phytother Res2013，27，6： | 1 |
| 4 | Colocalizatlon of somatostatin receptor sst5 and insulin in rat pancreatic β-cell 显示文摘 | Mitra SW Mezey E Hunyady B | 1999 | Endocrinology1999，140，： | 1 |
| 5 | Cell specific expression of the sst2A and sst5 somatostatin receptors in the rat anterior pituitary显示文摘 | Mezey E Hunyady B Mitra S | 1998 | Endocrinology1998，139，1： | 1 |
| 6 | Endoplasmic reticulum: nutrient sensor in physiology and pathology显示文摘 | József Mandl Tamás Mészáros Gábor Bánhegyi László Hunyady Miklós Csala | 2009 | Trends in Endocrinology & Metabolism2009，，4： | 1 |
| 7 | Side-effects of pegylated inter- feron plus ribavirin therapy with or without protease inhibitor direct acting antiviral agents during treatment of chronic hepatitis C virus infection 显示文摘 | Hunyady B Kov6cs B Batty6ni Z | 2011 | Orv Hetil2011，152，50： | 1 |
| 8 | Management of adverse effects of Peg-IFN and ribavirin therapy for hepati- tis C显示文摘 | Sulkowski MS Cooper C Hunyady B | 2011 | Nat Rev Gastroenterol Hepatol2011，8，4： | 1 |
| 9 | Gastrointestinal immunolo- gy: cell types in the lamina propria-A morphological review显示文摘 | Hunyady B Mezcy E Palkovits M | 2000 | Acta Physiol Hung2000，87，： | 1 |
| 10 | Colocalization of somatostatin receptor sst5 and insulin in rat pancreatic β - cell 显示文摘 | Mitra SW Mezey E Hunyady B | 1999 | Endocrinology1999，140，8： | 1 |
| 11 | Management of adverse effects of Peg-IFN and ribavirin therapy for hepa- titis C 显示文摘 | Sulkowski M S Cooper C Hunyady B | 2011 | Nat Rev Gastroenterol Hepatol2011，8，4： | 1 |
| 12 | Immunohistochemical signal amplification by catalyzed reporter deposition and its application in double immunostaining显示文摘 | Hunyady B Krempels K Harta G | 1996 | J Histochem Cytochem1996，44，12： | 1 |
| 13 | Immunohistochemical signal amplification by catalyzed reporter deposition and its application in double immunostaining显示文摘 | Krempels K Harta G | 1996 | J Histochem Cytochem1996，44，12： | 1 |
| 14 | Changes of plasma fasting carnitine ester profile in patients with ulcerative colitis显示文摘瞄准:与溃疡的 culitis (UC ) 并且与健康控制题目相比在成年病人决定血浆肉毒碱酉旨侧面。方法:用 ESI 三倍的四极双人脚踏车团分光术,肉毒碱酉旨侧面与 UC 和 44 匹配年龄、匹配性的健康控制在 44 个病人被测量。结果:在免费肉毒碱与 UC 和健康控制在病人之间铺平的 fasting 没有有效差量。禁食 propionyl-(0.331 +/- 0.019 对 0.392 +/- 0.017 micromol/L ) , butyryl-(0.219 +/- 0.014 对 0.265 +/- 0.012 ) ,并且 isovalerylcarnitine (0.111 +/- 0.008 对 0.134 +/- 0.008 ) 层次在 UC 病人被减少。由对比,octanoyl-的水平( 0.147 +/- 0.009 对 0.114 +/- 0.008 ),decanoyl-( 0.180 +/- 0.012 对 0.137 +/- 0.008 ),myristoyl-( 0.048 +/- 0.003 对 0.039 +/- 0.003 ),palmitoyl-( 0.128 +/- 0.006 对 0.109 +/- 0.004 ),palmitoleyl-( 0.042 +/- 0.003 对 0.031 +/- 0.002 )并且 oleylcarnitine ( 0.183 +/- 0.007 对 0.163 +/- 0.007 ;P <
0.05 在所有比较) 与 UC 在病人被增加。结论:我们的数据在 UC 病人建议肉毒碱酉旨的选择参与,可能由于他们的改变的新陈代谢。 | Judit Bene Katalin Komlósi Viktória Havasi Gábor Talián Beáta Gasztonyi Krisztina Horváth Gyula Mózsik Béla Hunyady Béla Melegh Mária Figler | 2006 | World Journal of Gastroenterology2006，12，1： | 1 |
| 15 | Clinical and pharmacological aspects of ri-faximin, local antibiotic therapy in intestinal disorders显示文摘 | Gasztonyi B Hunyady B | 2004 | Orv Hetil2004，145，43： | 1 |
| 16 | Clinical and pharmacological aspects of rifaximin ,local antibiotic therapy in intestinal disorders 显示文摘 | GASZTONYI B HUNYADY B | 2004 | Orv Hetil2004，145，43： | 1 |
| 17 | In vitro Anti-diabetic Activity and Chemical Characterization of an Apolar Frac- tion of Morus alba Leaf Water Extract 显示文摘 | Hunyadi A Veres K Danko B | 2013 | Phytother Res2013，27，6： | 1 |
| 18 | Management of adverse effects of Peg-IFN and ribavirin therapy for hepatitis C 显示文摘 | Sulkowski MS Cooper C Hunyady B | 2011 | Nat Rev Gastroenterol Hepatol2011，8，4： | 1 |
| 19 | Immuno- histochemical localization of soraatostatin receptor SST2 A in the rat pancreas显示文摘 | Hunyady B Hipkin RW Schonbrunn A | 1997 | Endocrinology1997，138，7： | 1 |
| 20 | Evaluation of Ultrasound-based Surveillance for Hepatocellular Carcinoma in Patients at Risk:Results From a German Multicenter Retrospective Cohort Study显示文摘Background and Aims:Hepatocellular carcinoma(HCC)surveillance in patients at risk is strongly recommended and usually performed by ultrasound(US)semiannually with or without alfa-fetoprotein(AFP)measurements.Quality pa-rameters except for surveillance intervals have not been strictly defined.We aimed to evaluate surveillance success and risk factors for surveillance failure.Methods:Patients with≥1 US prior to HCC diagnosis performed at four tertiary referral hospitals in Germany between 2008 and 2019 were retrospectively analyzed.Surveillance success was defined as HCC detection within Milan criteria.Results:Only 47%of 156 patients,median age 63(interquartile range:57-70)years,56%male,and 96%with cirrhosis,received recom-mended surveillance modality and interval.Surveillance fail-ure occurred in 29%and was significantly associated with lower median model for end-stage liver disease(MELD)score odds ratio(OR)1.154,95%confidence interval(CI):1.027-1.297,p=0.025)and HCC localization within right liver lobe(OR:6.083,95%CI:1.303-28.407,p=0.022),but not with AFP≥200μg/L.Patients with surveillance failure had sig-nificantly more intermediate/advanced tumor stages(93%vs.6%,p<0.001),fewer curative treatment options(15%vs.75%,p<0.001)and lower survival at 1 year(54%vs.75%,p=0.041),2 years(32%vs.57%,p=0.019)and 5 years(0%vs.16%,p=0.009).Alcoholic and non-alcoholic fatty liver disease(OR:6.1,95%CI:1.7-21.3,p=0.005)and ascites(OR:3.9,95%CI:1.2-12.6,p=0.021)were in-dependently associated with severe visual limitations on US.Conclusions:US-based HCC surveillance in patients at risk frequently fails and its failure is associated with unfavorable patient-related outcomes.Lower MELD score and HCC lo-calization within right liver lobe were significantly associated with surveillance failure. | Johannes Gillessen Philipp Reuken Peter-Marton Hunyady Matthias Christian Reichert Lucian Lothschütz Fabian Finkelmeier Matthias Nowka Gabriel Allo Fabian Kütting Martin Bürger Dirk Nierhoff Hans-Michael Steffen Christoph Schramm | 2023 | Journal of Clinical and Translational Hepatology2023，11，3： | 0 |
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