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2篇 您的检索式:作者名="Hubert Appert"
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1Effects of Taxotere on invasive potential and multidrug resistance phenotype in pancreatic carcinoma cell line SUIT-2显示文摘INTRODUCTIONDevelopment of drug-resistance to chemotherapyand subsequent metastasis of tumor are primarilyresponsible for treatment failure and the death fromcancer. There have been many previous studies onthe relationship between expression of multidrugresistance (MDR) phenotype P-glycoprotein (P-gp)and the malignant properties of tumors, but theresults are often conflicting[1-8]. The difference intumor types or MDR phenotype induced by specificagents might account for this discrepancy. Taxotere(TXT), a member of the family of taxanes, hasantitumor activity through its effect of promotingthe polymerization of tubulin[9,10].Edgar Staren Takeshi Iwamura Hubert Appert John Howard 2001World Journal of Gastroenterology2001,7,1:12
2Mechanisms of Taxotere-Related Drug Resistance in Pancreatic Carcinoma显示文摘Bin Liu Edgar D. Staren Takeshi Iwamura Hubert E. Appert John M. Howard 2001Journal of Surgical Research2001,,2:1
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