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| 1 | Polysaccharide conjugate vaccine:A kind of vaccine with great development potential显示文摘Diseases caused by microbial bacteria such as Haemophilus influenzae type b(Hib),Streptococcus pneumoniae and Neisseria meningitidis are still very serious disease,which has brought a lot of burden to many countries.Development of vaccine has brought hope for the prevention of such diseases.Polysaccharide conjugate vaccines have been shown to have very good effects in preventing such diseases.The polysaccharide co njugate vaccine adds the positive characteristics of protein antigens to the polysaccharide antigen,thereby improving the immunogenicity of the polysaccharide antigen,solving the problem that the polysaccharide vaccine cannot be effectively applicated in toddler or children,which greatly promoting the development of this vaccine.This review introduces the progress of polysaccharide conjugate vaccines.We introduce the typical polysaccharide conjugate vaccines currently on the market firstly,and then elucidate the protein carriers,the coupling chemistry methods and quality control that required in the preparation of polysaccharide conjugate vaccines.We can see that polysaccharide conjugate vaccine is a kind of vaccine with great development potential,which can be a sharp edge for us to prevent diseases. | Jing Zhao Gang Hud Yi Huang Yingchun Huang Xin Wei Jianyou Shi | 2021 | Chinese Chemical Letters2021，32，4： | 2 |
| 2 | Prevalence and significance of acanthosis nigricans in an adult obese population显示文摘 | Hud JA Jr Cohen JB Wagner JM | 1992 | Arch Dermatol1992，128，7： | 1 |
| 3 | Regulation of hypox- ia-inducible factor-1 alpha expression and function by the mammalian target of rapamycin显示文摘 | Huds on CC Liu M Chiang GG | 2002 | Mol Cell Biol2002，22，70： | 1 |
| 4 | DNA-templated Ag nanocluster formation显示文摘 | PETTY J T ZHENG Jie HUD N V | 2004 | J Am Chem Soc2004，126，： | 1 |
| 5 | Prevalence and significance of acanthosis nigricans in an adult obese population显示文摘 | Hud JA Jr Cohen JB Wagner JM | 1992 | Arch Der- matol1992，128，7： | 1 |
| 6 | Tip-radius-induced artifacts in AFM images of protamine-com-plexed DNA fibers显示文摘 | Allen M J Hud N V Balooch M | 1992 | Ultramicroscopy1992，42，： | 1 |
| 7 | Prevalence and significance of acanthosis nigricans in an adult obese population显示文摘 | Hud JA Jr Cohen JB Wagner JM | 1992 | Arch Dermatol1992，128，7： | 1 |
| 8 | Vitreous fluid of db/db mice exhibits alterations in angiogertic and metabolic factors consistent with early diabetic retinopathy显示文摘 | Cohen MP Hud E Shea E | 2008 | Ophthalmic2008，40，1： | 1 |
| 9 | Upper cervical facet joint and spinal rami blocks for the treatment of cervicogenic headache 显示文摘 | Zhou L Hud - Shakoor Z Hennessey C | 2010 | Headache2010，50，4： | 1 |
| 10 | Linear response theory in stochastic resonance 显示文摘 | M I Dykman H Hakenb Gang Hud D G Luchinskya R Mannellaa P V E McClintocka C Z Ninggb N D Steina N G Stockse | 1993 | Physics Letters A1993，180，45： | 1 |
| 11 | The effect of sodium,potassium and ammonium ions on the conformation of the dimeric quadruplex formed by the Oxytricha nova telomere repeat oligonucleotide d(G4T4G4)显示文摘 | Schultze P Hud N V Smith F W | | 0，，15： | 1 |
| 12 | InteractionsofmiR-323/miR-326/miR-329andmiR-130a/miR-155/miR-210asprognosticindicatorsforclinicaloutcomeofglioblastomapatients显示文摘 | QiuS LinS HuD etal | 2013 | JTranslMed2013，11，10： | 1 |
| 13 | Effect of boron addition on tensile ductility in lamellar TiAl alloys显示文摘 | | 2002 | Intermetallics2002，10，9： | 1 |
| 14 | Epidemiology, risk factors for stroke, and management of atrial fibrillation in China显示文摘 | HuD SunY | 2008 | J Am Coll Cardiol2008，52，10： | 1 |
| 15 | Ormation of native-like mammalian sperm cell chromatin with folded bull protamine 显示文摘 | VILFAN I D CONWELL C C HUD N V | 2004 | J Biol Chem2004，279，20： | 1 |
| 16 | Excess insulin binding to insulin-like growth factor receptors:proposed mechanism for acanthosis nigricans显示文摘 | Cruz P Hud J | 1992 | J Invest Dermatol1992，98，： | 1 |
| 17 | Controlling the size of nanoscale toroidal DNA condensates with static curvature and ionic strength显示文摘 | CHRISTINE C CONWELL VILFAN IGOR D HUD NICHOLAS V | 2003 | PNAS2003，100，16： | 1 |
| 18 | Inhibiting albumin glycation attenuates dysregulation of VEGFR-1 and collagen Ⅳ subchain production and the development of renal insufficiency显示文摘 | Cohen MP Lautenslager GT Hud E | 2007 | American Journal of Physiology-Renal Physiology2007，292，2： | 1 |
| 19 | Inhibition of late sodium current by mexiletine:a novel pharmotherapeutical approach in timothy syndrome显示文摘 | GaoY XueX HuD | 2013 | Circ Arrhythm Electrophysiol2013，6，： | 1 |
| 20 | Central rather than overall obesity is related to diabetes in the Chinese population: the interASIA study显示文摘 | HuD XieJ FuP | 2007 | Obesity(Silver Spring)2007，15，28： | 1 |
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