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12篇 您的检索式:作者名="Horata"
    题名 作者 年代 出处 被引量
1Robust extreme learning machine显示文摘HORATA P CHIEW CHANWATTANA S SUNAT K 2013Neurocomputing2013,102,15:1
2Acquisition of naturally acquired antibody response to Plasmodium falciparum erythrocyte membrane protein 1-DBLα and differential regulation of IgG subclasses in severe and uncomplicated malaria显示文摘Objectives: To explore whether individuals infected with Plasmodium falciparum(P. falciparum) develop antibodies directed against Pf EMP1-DBLa, and to assess their IgG subclass distribution in severe and uncomplicated malaria.Methods: The anti-PfDBLα IgG and their IgG subclass distributions in plasma of severe(SM) and uncomplicated malaria(UCM) were assessed by enzyme-linked immunoabsorbent assay. The antibody profiles to P. falciparum blood stage antigens were evaluated. CD36 binding ability was determined by static receptor-binding assays.Rosette formation was performed by staining with acridine orange.Results: Significantly higher number of UCM(86.48%) than SM(57.78%) plasma contained total acquisition of specific IgG to P. falciparum antigens(P = 0.000). Similar manners were seen in response to P. falciparum DBLa with significant difference(UCM,59.46% vs SM, 40.00%; P = 0.014). Anti-PfDBLα-IgG1 and-IgG3 were the predominant subclasses. Similar percentage of UCM(31.82%) and SM(33.33%) plasma contained only IgG1, while 13.64% of UCM and 27.78% of SM plasma contained only IgG3. AntiPfDBLα-IgG1 coexpressed with more than one subclass was noted(UCM, 27.27%; SM,16.67%). Obviously, IgG1 coexpressed with IgG3(9.09%) was observed in only UCM plasma. IgG1 was coexpressed with IgG2 in UCM(9.09%) and SM(11.11%) plasma,while IgG1 was coexpressed with IgG4 only in UCM plasma(4.55%). IgG subclasses to P. falciparum antigens were distributed in a similar manner. Only the levels of IgG1, but not IgG3 were significantly higher in UCM than in SM.Conclusions: These data suggest that individuals infected with P. falciparum can develop the anti-Pf EMP1 antibodies with the major contribution of specific IgG subclasses. The balance and the levels of anti-PfDBLα IgG subclasses play a crucial role in antibody mediated protection against severe malaria.Natharinee Horata Kiattawee Choowongkomon Siriluk Ratanabunyong Jarinee Tongshoob Srisin Khusmith 2017Asian Pacific Journal of Tropical Biomedicine2017,7,12:1
3Robust extreme learning machine显示文摘Horata P Chiewchanwattana S Sunat K 2013Neurocomputing2013,102,:1
4Development of Titanium and Titanium Alloy by Metal Injection Molding Process显示文摘 Horata tetsuya Kondo 1997Journal of the Japan Society of Powder and Metallurgy1997,44,11:1
5Robust extreme learning machine 显示文摘Horata P Chiewchanwattana S Sunat K 2013Neurocomputing2013,102,:1
6Robust extreme learning machine显示文摘Horata P Chiewchanwattana S Sunat K 0,,:1
7Robust extreme learning machine显示文摘Horata P Chiewchanwattana S Sunat K 2013Neurocomputing2013,,102:1
8Robust ex- treme learning machine 显示文摘HORATA P CHIEWCHANWATrANA S SUNAT K 2013Neurocomputing2013,102,:1
9Robust extreme learning machine显示文摘Punyaphol Horata Sirapat Chiewchanwattana Khamron Sunat 2013Neurocomputing2013,,:1
10Robust extreme learning machine显示文摘Horata P Chiewchanwattana S and Sunat K 2013Neurocomputing2013,102,:1
11Robust extreme learning machine 显示文摘HORATA P CHIEWCHANWATTAN S SUNATK 2013Neurocom- puting2013,102,:1
12Robust extreme learning machine显示文摘Horata P Chiewchanwattana S Sunat K 2013Neurocomputing2013,10,2:1
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