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61篇 您的检索式：作者名="Hopley"

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	题名	作者	年代	出处	被引量
1	Characterisation and risk assessment of venous thromboembolism in gastrointestinal cancers显示文摘AIM To characterise venous thromboembolism(VTE) in gastrointestinal cancer and assess the clinical utility of risk stratification scoring. METHODS We performed a retrospective analysis using electronic patient records of 910 gastro-oesophageal(GO) cancer and 1299 colorectal cancer(CRC) patients referred to a tertiary cancer centre to identify the incidence of VTE, its relationship to chemotherapy and impact on survival.VTE risk scores were calculated using the Khorana index. Patients were classified as low risk(0 points), intermediate risk(1 to 2 points) or high risk(3 points). Data was analysed to determine the sensitivity of the Khorana score to predict VTE. RESULTS The incidence of VTE was 8.9% for CRC patients and 9.7% for GO cancer patients. Pulmonary emboli(PE) were more common in advanced than in localised CRC(50% vs 21% of events respectively) and lower limb deep vein thrombosis(DVT) were more common in localised than in advanced CRC(62% vs 39% of events respectively). The median time to VTE from cancer diagnosis was 8.3 mo for CRC patients compared to 6.7 mo in GO cancer. In localised CRC median time to VTE was 7.1 mo compared with 10.1 mo in advanced CRC. In contrast in GO cancer, the median time to VTE was 12.5 mo in localised disease and 6.8 mo in advanced disease. No survival difference was seen between patients with and without VTE in this cohort. The majority of patients with CRC in whom VTE was diagnosed had low or intermediate Khorana risk score(94% for localised and 97% in advanced CRC). In GO cancer, all patients scored either intermediate or high risk due to the primary site demonstrating a limitation of the risk assessment score in discriminating high and low risk patients with GO cancers. Additional risk factors were identified in this cohort including surgery, chemotherapy or hospital admission. Overall, 81% of patients with CRC and 77% of patients with GO cancer had one or more of these factors within 4 wk prior to diagnosis VTE. These should be factored into clinical risk assessment scores. CONCLUSION The Khorana score has low sensitivity for thrombotic events in CRC and cannot discriminate low risk patients in high risk cancer sites such as GO cancer.	Robert L Metcalf Eamon Al-Hadithi Nicholas Hopley Thomas Henry Clare Hodgson Antony McGurk Wasat Mansoor Jurjees Hasan	2017	World Journal of Gastrointestinal Oncology2017，9，9：	10
2	Primary total hip arthroplasty versus hemiarthmplasty for displaced int- racapsular hip fractures in older patients:systematic rev- iew显示文摘	Hopley C Stengel D Ekkemkamp A	2010	BMJ2010，340，：	1
3	Water-mediated lysis of lens epithelial cells attached to lens capsule 显示文摘	Crowston JG HealeyPR Hopley C	2004	Cataract Re- fract Surg2004，30，5：	1
4	Percutaneous embolotherapy for life threatening hemoptysis显示文摘	Wong ML Szkup P Hopley MJ	2002	Chest2002，121，1：	1
5	Temperature and surface-ocean water balance of the mid-Holocene tropical western Pacific显示文摘	Gagan M K Ayliffe L K Hopley D	1998	Science1998，279，：	1
6	Optimal reactor structures for exothermic reversible reactions with complex kinetics显示文摘	Hopley F Glasser D Hildebrandt D		Chem Eng Sci0，10，：	1
7	The application of 33P-labeling in the electrophoretic mobility shift assay 显示文摘	Wolf SS Hopley JG Schweizer M	1994	Biotechniques1994，16，4：	1
8	Percutaneous embolotherapy for life-threatening hemoptysis显示文摘	Wong ML Szkup P Hopley MJ	2002	Chest2002，121，：	1
9	Primary total hip arthro- plasty versus hemiarthroplasty for displaced intraeapsular hip fractures in older patients : systematic review 显示文摘	Hopley C Stengel D Ekkernkamp A	2010	BMJ2010，340，：	1
10	A decade of stigma and dis- crimination in mental health:plus ca change, plus c'estla meme cho- selthe more things change, the more they stay the same 显示文摘	Lyons C Hopley P Horrecks J	2009	J Psy- ehiatr Ment Health Nurs2009，16，6：	1
11	High accuracy determination of malachite green and leucomalachite green in salmon tis- sue by exact matching isotope dilution mass spectrometry 显示文摘	HALL Z HOPLEY C OCONNOR G	2008	Journal of Chromatography B2008，874，：	1
12	Primary total hip arthroplasty versus hemiarthroplasty for displaced intracapsular hip fractures in older patients:systematic review显示文摘	Hopley C Stengel D Ekkernkamp A		0，，340：	1
13	Primary total hip arthro-plasty versus hemiarthroplasty for displaced intracapsular hip frac-tures in older patients:systematic review显示文摘	Hopley C Stengel D Ekkernkamp A	2010	BMJ2010，340，：	1
14	Long-term clinical outcomes and survivorship after total knee arthroplasty using a rotating platform knee prosthesis:a meta-analysis显示文摘	Hopley CD Crossett LS Chen AF		0，，：	1
15	Temperature and Surface-Ocean Water Balance of the Mid-Holocene Tropical Western Pacific显示文摘	Gagan M K Ayliffe L K Hopley D	1997	Science1997，279，：	1
16	Primary total hip arthroplasty versus hemiarhroplasty for displaced intracapsular hip fractures in older patients:systematic review显示文摘	Hopley C Stengel D Ekkernkamp A	2010	BMJ2010，340，：	1
17	Primary total hip arthroplasty versus hemiarthroplasty for displaced intraeapsular hip fractures in older patients:systematic review显示文摘	Hopley C Stengel D Ekkernkamp A	2010	BMJ2010，22，34：	1
18	Primary total hip atthroplasty versus hemiarthroplasty for displaced intracapsular hip fractures in older patients: systematic review显示文摘	Hopley C Stengel D Ekkemkamp A	2010	BMJ2010，11，340：	1
19	A decade of stigma and discrimination in mental health:the more things change,the more they stay the same显示文摘	Lyons C Hopley P Horrocks J et a1	2009	J Psyehiatr Ment Health Nurs2009，16，6：	1
20	Temperature and surface-ocean water balance of the mid-Holocene tropical western pacific显示文摘	Gagan M K Ayliffe L K Hopley D	1998	Science1998，279，5343：	1

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