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| 1 | Zircon U-Pb geochronology,Hf isotopic composition and geological implications of the rhyodacite and rhyodacitic porphyry in the Xiangshan uranium ore field,Jiangxi Province,China显示文摘The Xiangshan uranium ore field is the largest volcanic rock hosted uranium deposit in China.The host rock is a volcanic intrusive complex,including rhyodacite,porphyroclastic lava and late stage sub-volcanic rocks.In this study,zircons from an early stage rhyodacite and a late stage rhyodacite porphyry were dated by SHRIMP and LA-ICP-MS U-Pb methods,and their Hf isotopic compositions were measured by LA-MC-ICP-MS.206Pb/238U ages of 135.1±1.7 and 134.8±1.1 Ma were obtained for the rhyodacite and rhyodacitic porphyry,respectively.These accurate ages indicate that the Xiangshan volcanic-intrusive complex formed in the Early Cretaceous rather than in the Late Jurassic,as concluded in some previous studies.By the Early Cretaceous,the tectonic setting of the area has evolved into a back-arc extensional setting,possibly related to subduction of the paleo-Pacific plate.The close ages of the(early) eruptive rhyodacite and the(late) hypabyssal rhyodacitic porphyry shows that the Xiangshan volcanism was intensive and concentrated in a short time.Zircons from the rhyodacite show negative εHf(t) values of-5.7 to-8.5,with Hf depleted mantle model ages between 1550 and 1720 Ma,whereas zircons from the rhyodacitic porphyry yield εHf(t) values of-6.9 to-10.1 and Hf model ages between 1621 and 1823 Ma.These zircon Hf model ages are similar to the whole rock Nd model ages(1486 to 1911 Ma).Combined with other geochemical characteristics,the Xiangshan rhyodacite and rhyodacitic porphyry may have been derived from partial melting of the Paleo-Mesoproterozoic metamorphic rocks from the Xiangshan basement,without any significant addition of mantle-derived magma.Contribution of basement of this age is also supported by finding a Paleoproterozoic xenocrystic zircon core in the rhyodacite sample. | YANG ShuiYuan JIANG ShaoYong JIANG YaoHui ZHAO KuiDong FAN HongHai | 2010 | Science China Earth Sciences2010，53，10： | 40 |
| 2 | In-situ U-Pb dating of uraninite by fs-LA-ICP-MS显示文摘In this study,the Pb/U fractionation between zircon and uraninite during femtosecond Laser Ablation Inductively Coupled Plasma Mass Spectrometry(fs-LA-ICP-MS)analysis was studied in detail.The results show significant Pb/U fractionation between zircon and uraninite during fs-LA-ICP-MS analysis that when calibrated against the zircon standard M257,the obtained U-Pb age of the Chinese national uraninite standard GBW04420 is 17%older than the recommended value.Thus,the accurate in-situ U-Pb dating of uraninite by LA-ICP-MS requires matrix-matched external standards for calibration.Uraninite in thin sections of two U-mineralized leucogranite from the Gaudeanmus in Namibia was analyzed by a fs-LA-ICP-MS equipped with a Signal Smooth Device(SSD),using laser spot and frequency of 10μm and 1 Hz,respectively.When calibrated using GBW04420 as the external standard,two samples give weighted mean 206Pb/238U ages of 504±3 Ma(2σ,n=21)and503±3 Ma(2σ,n=22),and only one of two samples yields a concordia U-Pb age of 507±1 Ma(2σ,n=21).These results are consistent with ID-TIMS U-Pb ages of 509±1 and 508±12 Ma and are also indistinguishable from zircon U-Pb upper intercept ages of 506±33 Ma(2σ,n=29)and 501±51 Ma(2σ,n=29).The present study shows that in-situ U-Pb dating of uraninite can deliver more reliable formation ages of the deposit than dating coeval high-U zircon because the latter commonly suffer significant Pb loss after formation.Our results confirm that GBW04420 is an ideal matrix matching standard for in-situ U-Pb dating of uraninite. | ZONG KeQing CHEN JinYong HU ZhaoChu LIU YongSheng LI Ming FAN HongHai MENG YanNing | 2015 | Science China Earth Sciences2015，58，10： | 22 |
| 3 | Dynamic characteristics of an intestine capsule robot with variable diameter显示文摘This paper proposes an intestine capsule robot with variable diameter. It is driven by external rotating magnetic field and has the function of automatic radial clearance compensation. An external magnetic field generating device and a capsule robot with variable diameter are developed. Radial dynamic balance equation and kinematics equation of the capsule robot traveling inside flexible elasto-wall environment are established, and dynamic characteristics of the capsule robot inside flexible elasto-wall pipe and rigid wall pipe environments are analyzed and compared. Simulations and experiment results show that its dynamic characteristics in both pipes are almost the same. Under the action of radial clearance compensation, fluid dynamic pressure around outer surface of the capsule robot and its propulsion, as well as its adaptability to diameter change range, are significantly improved. Its propulsion and moving speed are controlled by adjusting rotating angular speed of the rotating magnetic field. This innovative capsule robot with radial clearance compensation has a promising prospect for inside intricate gastrointestinal (GI) tract in non-invasive therapy applications. | ZHANG YongShun JIANG ShengYuan ZHANG XueWen YU HongHai WANG DianLong GUO DongMing | 2010 | Chinese Science Bulletin2010，55，17： | 11 |
| 4 | Outline of Uranium Resources Characteristics and Metallogenetic Regularity in China显示文摘Uranium,as one of twenty-six kinds of important minerals in China,is strategic resource and energy mineral,which has been thoroughly investigated in the project of National Potential Evaluation of Uranium Resource.During the implementation of this project,the authors summarized the metallogenic regularity of uranium resource in China systematically,through the researches of geological characteristics of uranium resource,uranium deposits type(genetic and prediction type),temporal and spatial distribution,and metallogenic series.Based on the investigation of present situation and progress in uranium exploration,this paper proposes the uranium deposits in China should be divided into 4 classes,9 types,21 subtypes in genetic,and 50 types in prediction;suggests to divide China into 29 uranium metallogenic belts and 20 uranium prospective area,and constructs 20uranium-polymetallic metallogenic series,through summarizing temporal and spatial distribution characteristics and metallogenic regularity of uranium deposits in China.The above research is beneficial to the comprehensive understanding of regional uranium metallogenic regularity,and will direct the uranium exploration in the future. | CAI Yuqi ZHANG Jindai LI Ziying GUO Qingyin SONG Jiye FAN Honghai LIU Wusheng QI Fucheng ZHANG Minglin | 2015 | Acta Geologica Sinica(English Edition)2015，89，3： | 11 |
| 5 | Nutritional compositions of various potato noodles:Comparative analysis显示文摘In this study,three kinds of noodles,wheat,Shepody potato and Atlantic potato noodles,were produced with blended powder consisting of wheat flour and certain amounts of various potato flours.In order to investigate the effects of potato flour on the nutritional characteristics of noodles,the nutrient compositions of four types of noodles were analyzed:fresh noodle,dried noodle,fresh noodle after boiling,and dried noodle after boiling.Results showed that the contents of protein,crude fiber,total ash,reducing sugar,vitamin B1,vitamin B2,vitamin B3,vitamin C,most mineral elements,dietary fiber,and amino acids in potato noodles were higher than those in wheat noodles.Furthermore,drying and boiling could decrease the contents of vitamin B1,vitamin B3,and mineral elements in noodles,but the nutrient contents in potato noodles remained higher than those in wheat noodles.The comprehensive nutritional values of noodles were evaluated using the index of nutritional quality,the results showed that the nutritional value of Shepody potato noodles was the highest,followed by that of Atlantic potato noodles and then wheat noodles. | Xu Fen Hu Honghai Dai Xiaofeng Liu Qiannan Huang Yanjie Zhang Hong | 2017 | International Journal of Agricultural and Biological Engineering2017，10，1： | 9 |
| 6 | Effects of cotton field management practices on soil CO2 emission and C balance in an arid region of Northwest China显示文摘Changes in both soil organic C storage and soil respiration in farmland ecosystems may affect atmospheric CO2 concentration and global C cycle. The objective of this field experiment was to study the effects of three crop field management practices on soil CO2 emission and C balance in a cotton field in an arid region of Northwest China. The three management practices were irrigation methods(drip and flood), stubble managements(stubble-incorporated and stubble-removed) and fertilizer amendments(no fertilizer(CK), chicken manure(OM), inorganic N, P and K fertilizer(NPK), and inorganic fertilizer plus chicken manure(NPK+OM)). The results showed that within the C pool range, soil CO2 emission during the whole growing season was higher in the drip irrigation treatment than in the corresponding flood irrigation treatment, while soil organic C concentration was larger in the flood irrigation treatment than in the corresponding drip irrigation treatment. Furthermore, soil CO2 emission and organic C concentration were all higher in the stubble-incorporated treatment than in the corresponding stubble-removed treatment, and larger in the NPK+OM treatment than in the other three fertilizer amendments within the C pool range. The combination of flood irrigation, stubble incorporation and application of either NPK+OM or OM increased soil organic C concentration in the 0-60 cm soil depth. Calculation of net ecosystem productivity(NEP) under different management practices indicated that the combination of drip irrigation, stubble incorporation and NPK+OM increased the size of the C pool most, followed by the combination of drip irrigation, stubble incorporation and NPK. In conclusion, management practices have significant impacts on soil CO2 emission, organic C concentration and C balance in cotton fields. Consequently, appropriate management practices, such as the combination of drip irrigation, stubble incorporation, and either NPK+OM or NPK could increase soil C storage in cotton fields of Northwest China. | QianBing ZHANG Ling YANG ZhenZhu XU YaLi ZHANG HongHai LUO Jin WANG WangFeng ZHANG | 2014 | Journal of Arid Land2014，6，4： | 8 |
| 7 | Genesis and Uranium Sources of Leucogranite-hosted Uranium Deposits in the Gaudeanmus Area, Central Damara Belt, Namibia: Study of Element and Nd Isotope Geochemistry显示文摘This paper presents a systematic study of major and trace elements and Sm-Nd isotopes in leucogranites closely related to uranium mineralization in the Gaudeanmus area, Namibia. The results illustrate that the uraniferous leucogranites possess high Si_O_2(68.8 wt%–76.0 wt%, average 73.1 wt%) and K(4.05 wt%–7.78 wt%, average 5.94 wt%) contents, and are sub-alkaline and metaluminous to weakly peraluminous, as reflected by A/CNK values of 0.96–1.07 with an average of 1.01. The leucogranites are rich in light rare earth elements(LREE/HREE = 2.53–7.71;(La/Yb)N = 2.14–10.40), have moderate Eu depletion and high Rb/Sr ratios(2.03–5.50 with an average of 4.36); meanwhile, they are enriched in Rb, K, Th, U and Pb, and depleted in Ba, Nb, Ta, and Sr. The ε_(Nd)(t) values of uraninites range from -14.8 to -16.5, and the two-stage Nd model ages are 2.43–2.56 Ga. Detailed elemental and Sm-Nd isotopic geochemical characteristics suggest that the leucogranites were formed in a postorogenic extensional environment. The U-rich pre-Damara basement was the main source of uranium during the primary mineralization event, which is disseminated in leucogranites, whereas the uranium mineralization in veins possibly resulted from remobilization of the primary uranium minerals. | FAN Honghai CHEN Jinyong WANG Shengyun ZHAO Jingyang GU Dazhao MENG Yanning | 2017 | Acta Geologica Sinica(English Edition)2017，91，6： | 7 |
| 8 | Progesterone promotes neuronal differentiation of human umbilical cord mesenchymal stem cells in culture conditions that mimic the brain microenvironment显示文摘In this study, human umbilical cord mesenchymal stem cells from full-term neonates born by vaginal delivery were cultured in medium containing 150 mg/mL of brain tissue extracts from Sprague-Dawley rats (to mimic the brain microenvironment). Immunocytochemical analysis demonstrated that the cells differentiated into neuron-like cells. To evaluate the effects of progesterone as a neurosteroid on the neuronal differentiation of human umbilical cord mesenchymal stem cells, we cultured the cells in medium containing progesterone (0.1, 1, 10 μM) in addition to brain tissue extracts. Reverse transcription-PCR and flow cytometric analysis of neuron specific enolase-positive cells revealed that the percentages of these cells increased significantly following progesterone treatment, with the optimal progesterone concentration for neuron-like differentiation being 1 μM. These results suggest that progesterone can enhance the neuronal differentiation of human umbilical cord mesenchymal stem cells in culture medium containing brain tissue extracts to mimic the brain microenvironment. | Xianying Wang Honghai Wu Gai Xue Yanning Hou | 2012 | Neural Regeneration Research2012，7，25： | 7 |
| 9 | Metabolic alteration of neuroactive steroids and protective effect of progesterone in Alzheimer's disease-like rats显示文摘A correlation between metabolic alterations of neuroactive steroids and Alzheimer's disease remains unknown. In the present study, amyloid beta(Aβ) 25–35(Aβ25–35) injected into the bilateral hippocampus CA1 region significantly reduced learning and memory. At the biochemical level, hippocampal levels of pregnenolone were significantly reduced with Aβ25–35treatment. Furthermore, progesterone was considerably decreased in the prefrontal cortex and hippocampus, and 17β-estradiol was significantly elevated. To our knowledge, this is the first report showing that Aβ25–35, a main etiological factor of Alzheimer's disease, can alter the level and metabolism of neuroactive steroids in the prefrontal cortex and hippocampus, which are brain regions significantly involved in learning and memory.Aβ25–35exposure also increased the expression of inflammatory mediators, tumor necrosis factor-αand interleukin-1β. However, subcutaneous injection of progesterone reversed the upregulation of tumor necrosis factor-α and interleukin-1β in a dose-dependent manner. Concomitant with improved cognitive abilities, progesterone blocked Aβ-mediated inflammation and increased the survival rate of hippocampal pyramidal cells. We thus hypothesize that Aβ-mediated cognitive deficits may occur via changes in neuroactive steroids. Moreover, our findings provide a possible therapeutic strategy for Alzheimer's disease via neuroactive steroids, particularly progesterone. | Sha Liu Honghai Wu Gai Xue Xin Ma Jie Wu Yabin Qin Yanning Hou | 2013 | Neural Regeneration Research2013，8，30： | 7 |
| 10 | A lentiviral vector-based therapeutic vaccine encoding Ag85B-Rv3425 potently increases resistance to acute tuberculosis infection in mice显示文摘为 multidrug 抵抗的肺结核(TB ) 和到为 TB 的新奇治疗学的途径的发展的广泛地药抵抗的 TB 电话注意的很少处理选择。因为他们能导致抗原特定的细胞的有免疫力的回答,治疗学的疫苗正在答应候选人,它在 Mycobacterium 肺结核(鱼雷快艇) 的消除起一个重要作用。在这研究,新奇 lentiviral 向量为交付鱼雷快艇特定的熔化蛋白质 Ag85B-Rv3425 的治疗学的疫苗被构造。结果证明这支 recombinant lentivirus 疫苗单个注射的能在老鼠触发抗原特定的 Th1 类型有免疫力的回答。更重要地,有急性感染的老鼠在肺和脾由显著地减少的鱼雷快艇负担从这支疫苗的一个单个剂量的政府有益于很多以及与未经治疗的老鼠相比在肺稀释了损害。这些结果为 TB 的免疫疗法显示了这支新奇疫苗的好前景。 | Enzhuo Yang Feifei Wang Ying Xu Honghai Wang Yong Hu Hongbo Shen Zheng W. Chen | 2015 | Acta Biochimica et Biophysica Sinica2015，47，8： | 6 |
| 11 | Elevated Neurosteroids in the Lateral Thalamus Relieve Neuropathic Pain in Rats with Spared Nerve Injury显示文摘Neurosteroids are synthesized in the nervous system from cholesterol or steroidal precursors imported from peripheral sources. These compounds are important allosteric modulators of c-aminobutyric acid A receptors(GABA_ARs), which play a vital role in pain modulation in the lateral thalamus, a main gate where somatosensory information enters the cerebral cortex. Using high-performance liquid chromatography/tandem mass spectrometry,we found increased levels of neurosteroids(pregnenolone,progesterone, deoxycorticosterone, allopregnanolone, and tetrahydrodeoxycorticosterone) in the chronic stage of neuropathic pain(28 days after spared nerve injury) in rats.The expression of the translocator protein TSPO, the upstream steroidogenesis rate-limiting enzyme, increased at the same time. In vivo stereotaxic microinjection of neurosteroids or the TSPO activator AC-5216 into the lateral thalamus(AP-3.0 mm, ML ±3.0 mm, DV 6.0 mm)alleviated the mechanical allodynia in neuropathic pain,while the TSPO inhibitor PK 11195 exacerbated it. The analgesic effects of AC-5216 and neurosteroids were significantly attenuated by the GABA_AR antagonist bicuculline. These results suggested that elevated neurosteroids in the lateral thalamus play a protective role in the chronic stage of neuropathic pain. | Meng Zhang Jia Liu Meng-Meng Zhou Honghai Wu Yanning Hou Yun-Feng Li Yuxin Yin Lemin Zheng Feng-Yu Liu Ming Yi You Wan | 2016 | Neuroscience Bulletin2016，32，4： | 6 |
| 12 | Seasonal variations of dimethylsulfide (DMS) and dim-ethylsulfoniopropionate (DMSP) in the sea-surface microlayer and subsurface water of Jiaozhou Bay and its adjacent area显示文摘The distributions of DMS and its precursor dimethylsulfoniopropionate, in both dissolved (DMSPd) and particulate fractions (DMSPp) were determined in the sea-surface microlayer and correspond-ing subsurface water of the Jiaozhou Bay, China and its adjacent area in May and August 2006. The concentrations of all these components showed a clear seasonal variation, with higher concen-trations occurring in summer. This can be mainly attributed to the higher phytoplankton biomass observed in summer. Simultaneously, the enrichment extents of DMSPd and DMSPp in the mi-crolayer also exhibited seasonal changes, with higher values in spring and lower ones in summer. Higher water temperature and stronger radiant intensity in summer can enhance their solubility and photochemical reaction in the microlayer water, reducing their enrichment factors (the ratio of concentration in the microlayer to that in the corresponding subsurface water). A statistically significant relationship was found between the microlayer and subsurface water concentrations of DMS, DMSP and chlorophyll a, demonstrating that the biogenic materials in the microlayer come primarily from the underlying water. Moreover, our data show that the concentrations of DMSPp and DMS were significantly correlated with the levels of chlorophyll a, indicating that phytoplank-ton biomass might play an important role in controlling the distributions of biogenic sulfurs in the study area. The ratios of DMS/chlorophyll a and DMSPp/chlorophyll a varied little from spring to summer, suggesting that there was no obvious change in the proportion of DMSP producers in the phytoplankton community. The mean sea-to-air flux of DMS from the study area was estimated to be 5.70 μmol/(m2·d), which highlights the effects of human impacts on DMS emission. | ZHANG Honghai YANG Guipeng LIU Chunying LI Chenxuan | 2009 | Acta Oceanologica Sinica2009，28，2： | 6 |
| 13 | Preparation of phosphorus-modified PITQ-13 catalysts and their performance in 1-butene catalytic cracking显示文摘A series of phosphorus-modified PITQ-13 catalysts was prepared by wet impregnation of NH4H2PO4solution into an HITQ-13 parent. The catalysts were characterized using XRD, N2adsorption, MAS NMR and NH3-TPD. Their catalytic performance in 1-butene catalytic cracking was evaluated in a fixed fluidized bed reactor. The results showed that the crystallinity, surface area and pore volume of P-modified PITQ-13catalysts decreased with the increasing amounts of P. The number of weak acid sites increased, whereas that of strong acidity decreased. The selectivity to propylene in 1-butene cracking reactions increased because of the decrease in strong acidity. The yield of propylene achieved41.6% over PITQ-13-2 catalyst with a P content of 1.0 wt%, which was 5.1% greater than that achieved over HITQ-13 catalyst. | Penghui Zeng Yun Liang Shengfu Ji Baojian Shen Honghai Liu Baojie Wang Hongjuan Zhao Mingfu Li | 2014 | Journal of Energy Chemistry2014，23，2： | 6 |
| 14 | Relationship between plant canopy characteristics and photosynthetic productivity in diverse cultivars of cotton(Gossypium hirsutum L.)显示文摘Genotype and plant type affect photosynthetic production by changing the canopy structure in crops.To analyze the mechanism of action of heterosis and plant type on canopy structure in cotton(Gossypium hirsutum L.),we had selected two cotton hybrids(Shiza 2,Xinluzao 43) and two conventional varieties(Xinluzao 13,Xinluzao 33) with different plant types in this experiment.We studied canopy characteristics and their correlation with photosynthesis in populations of different genotypes and plant types during yield formation in Xinjiang,China.Canopy characteristics including leaf area index(LAI),mean foliage tilt angle(MTA),canopy openness(DIFN),and chlorophyll relative content(SPAD).The results showed that LAI and SPAD peak values were higher and their peak values arrived later,and the adjustment capacity of MTA during the flowering and boll-forming stages was stronger in Xinluzao 43,with the normal-leaf,pagoda plant type,than these values in other varieties.DIFN of Xinluzao 43 remained between0.09 and 0.12 during the flowering and boll-forming stages,but was lower than that in the other varieties during the boll-opening stage.Thus,these characteristics of Xinluzao 43 were helpful for optimizing the light environment and maximizing light interception,thereby increasing photosynthetic capability.The photosynthetic rate and photosynthetic area were thus affected by cotton genotype as changes in the adjustment range of MTA,increases in peak values of LAI and SPAD,and extension of the functional stage of leaves.Available photosynthetic area and canopy light environment were affected by cotton plant type as changes in MTA and DIFN.Heterosis expression and plant type development were coordinated during different growth stages,the key to optimizing the canopy structure and further increasing yield. | Guoyi Feng Honghai Luo Yali Zhang Ling Gou Yandi Yao Yongzeng Lin Wangfeng Zhang | 2016 | The Crop Journal2016，4，6： | 6 |
| 15 | An Efficient Method for Estimating Capability Curve of Virtual Power Plant显示文摘To incorporate the operating constraints of a virtual power plant(VPP)in transmission-level operation and market clearing,the concept of the VPP capability curve(VPP-CC)is proposed which explicitly characterizes the allowable range of active and reactive power outputs of a VPP.A two-step projection-based calculation framework is proposed to approximate the VPP-CC by the convex hull of critical points on its perimeter.The output of the proposed algorithm is concise and can be easily incorporated in the existing system operation and market clearing.Case studies based on the IEEE 33 and 123 test feeders show the computational efficiency of the proposed method outperforms existing methods by 4~7 times.Additionally,many fewer inequalities are needed to depict the VPP-CC while achieving the comparative approximation accuracy compared to sampling-based methods,which will relieve the communication and computation burden. | Zhenfei Tan Haiwang Zhong Xuanyuan Wang Honghai Tang | 2022 | CSEE Journal of Power and Energy Systems2022，8，3： | 5 |
| 16 | Genes and regulatory networks involved in persistence of Mycobacterium tuberculosis显示文摘The causative agent of tuberculosis,Mycobacterium tuberculosis,is one of the most successful of human pathogens.It can evade the host immune response and establish a persistent infection or enter a dormant state within the host which can be reactivated if the host becomes immuno-compromised.Both of these features are major obstacles to tuberculosis eradication.Dormancy and reactivation of M.tuberculosis are tightly coordinated dynamic processes involving numerous genes and their products.Molecular mechanisms underlying M.tuberculosis persistence may provide an opportunity for the discovery of effective drug targets for tuberculosis control.Here,we review the genes required for M.tuberculosis persistence and propose a regulatory network for the action of these genes using text mining.This should provide fresh insights into the persistence mechanisms of M.tuberculosis and suggest candidates for new drug targets and immune intervention. | WANG XiaoZhen WANG HongHai XIE JianPing | 2011 | Science China(Life Sciences)2011，54，4： | 4 |
| 17 | High-Speed Mach-Zehnder-OTDR Distributed Optical Fiber Vibration Sensor Using Medium-Coherence Laser显示文摘这篇文章介绍基于 Mach-Zehnder-OTDR (光时间域反射计) 察觉到的高速度的分布式的颤动。极端弱的纤维布拉格栅栏(UWFBG ) ,谁的向后点亮紧张,比散布的瑞利,被用作思考标记的高是 2-4 数量级。中等连贯的激光能代替常规狭窄的带宽来源自从我们的失衡的干涉仪匹配 UWFBG 的间隔,完成分布式的颤动察觉到的优秀表演。协调察觉和找到的多重同时的颤动消息提供者的空间分辨率的 3 m 能基于 OTDR 被认识到。没有平均,到噪音比率(SNR ) 的提高的信号启用分布式的颤动的快察觉。25 kHz 的最快的颤动和 10 Hz 的最慢的颤动能成功地与我们的系统被检测,并且线性与 3.46 n 的最大的偏差是 0.9896。 | Yuheng TONG Zhengying LI Jiaqi WANG Honghai WANG Haihu YU | 2018 | Photonic Sensors2018，8，3： | 4 |
| 18 | Pressure distributions on prism-shaped buildings in experimentally simulated downburst显示文摘Wind loading is one of the most significant factors in civil engineering that influences the structural design considerably.In this paper,a group of manufacturing equipments for downburst simulation based on impinging jet model was developed for investigating the wind loads on structures:including the centrifugal air bellows to generate airflow,a movable platform to realize multiple locations of the building and a freely rotatable turntable to implement alterable building angles.Hundreds of transducers were used to measure the wind action on all surfaces of the building.The pressure coefficients calculated from the observed data were utilized to evaluate the downburst wind load.Pressure distributions on three prism-shaped building models with different placements and angles were investigated to obtain the maximum wind action and mean pressure coefficients.The results showed that the maximum pressure coefficient would reach 1.0 on the top surface if the downburst just broke out over the edifice.Considering that the building was in the developing field of the downburst,the top and the front surfaces would be under high wind pressure and only the back surface would endure wind suction.When the downdraft happens away from the prismatic building,all surfaces,except the front surface,would subject to suction with different degrees.It was also found that the pressure coefficient on the right surface would get its negative peak at first and then go straight up to 0.6 as the angle changed from 0°to 45°and the wind pressure on the front surface would decrease slightly through the whole process.The assertive results provide elemental data for structural wind-resistant design in civil engineering for the downburst-prone areas. | LI HongHai OU JinPing | 2014 | Science China(Technological Sciences)2014，57，10： | 4 |
| 19 | Let-7b-5p regulates proliferation and apoptosis in multiple myeloma by targeting IGF1R显示文摘多重骨髓瘤(公里) 全球是从 hematological 恶意的死亡的最普通的原因,并且最近的研究表明了 let-7b-5p 能在 tumorigenesis 起一个禁止的作用。然而,在公里的 let-7b-5p 的角色仍然保持不清楚。这研究的目的是阐明 let-7b-5p 在公里由充当肿瘤 suppressor 的分子的机制。这里,量的即时聚合酶链反应结果证明 let-7b-5p 的表示显著地在公里纸巾和公里房间线(RPMI-8226 和 U266 房间) 被减少。而且, let-7b-5p 的在表示上显著地压制了 RPMI-8226 房间增长并且导致了 S/G2 房间周期拘捕和 apoptosis。酶记者试金结果证明(IGF1R ) 像胰岛素的生长因素受体 1 被 let-7b-5p 否定地在 post-transcriptional 水平调整。在 RPMI-8226 房间的 IGF1R 的 mRNA 和蛋白质层次由 let-7b-5p 是下面调整的。而且, let-7b-5p 禁止者改变的房间显型能被 IGF1R silencing (si-IGF1R ) 救。一起拿,我们的结果证明 let-7b-5p 在公里作为肿瘤 suppressor 工作,建议那 let-7b-5p 可以是为公里的一个潜在的治疗学的目标。 | Honghai Xu Cong Liu Yuelin Zhang Xiong Guo Zongzhi Liu Zhenqun Luo Yanhai Chang Shizhang Liu Zhengming Sun Xiaoqing Wang | 2014 | Acta Biochimica et Biophysica Sinica2014，46，11： | 4 |
| 20 | Experimental studies on dimethylsulfide (DMS) and dimethylsulfoniopropionate (DMSP) production by four marine microalgae显示文摘The production of dimethylsulfide (DMS) and dimethylsulfoniopropionate (DMSP) by marine microalgae was investigated to elucidate more on the role of marine phytoplankton in ocean-atmosphere interactions in the global biogeochemical sulfur cycle.Axenic laboratory cultures of four marine microalgae–Isochrysis galbana 8701,Pavlova viridis,Platymonas sp.and Chlorella were tested for DMSP production and conversion into DMS.Among these four microalgae,Isochrysis galbana 8701 and Pavlova viridis are two species of Haptophyta,while Chlorella and Platymonas sp.belong to Chlorophyta.The results demonstrate that the four algae can produce various amounts of DMS(P),and their DMS(P) production was species specific.With similar cell size,more DMS was released by Haptophyta than that by Chlorophyta.DMS and dissolved DMSP (DMSPd) concentrations in algal cultures varied significantly during their life cycles.The highest release of DMS appeared in the senescent period for all the four algae.Variations in DMSP concentrations were in strong compliance with variations in algal cell densities during the growing period.A highly significant correlation was observed between the DMS and DMSPd concentrations in algal cultures,and there was a time lag for the variation trend of the DMS concentrations as compared with that of the DMSPd.The consistency of variation patterns of DMS and DMSPd implies that the DMSPd produced by phytoplankton cells has a marked effect on the production of DMS.In the present study,the authors’ results specify the significant contribution of the marine phytoplankton to DMS(P) production and the importance of biological control of DMS concentrations in oceanic water. | LI Chengxuan YANG Guipeng PAN Jinfen ZHANG Honghai | 2010 | Acta Oceanologica Sinica2010，29，4： | 4 |
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