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| 1 | SPSBl-mediated HnRNP A1 alternative splicing and cell ubiquitylation regulates migration in EGF signaling显示文摘细胞外的信号被显示了影响拼接的其他的 pre-mRNA;然而,分子的机制和导致信号的拼接的规定的生物意义仍然保持大部分未知。这里,我们报导那个表皮的生长因素(EGF ) 通过一个著名拼接管理者的 ubiquitylation 导致拼接的变化, hnRNP A1。EGF 发信号 upregulates 一个 E3 ubiquitin (Ub ) ligase 适配器,敏捷的包含域的 SOCS 盒子蛋白质 1 (SPSB1 ) ,它结合离氨酸 29 连接 polyUb 链到 hnRNP A1 上的成员 Elongin B/C-Cullin 建筑群。重要地, hnRNP A1 的 SPSB1 和 ubiquitylation 在驾驶 EGF 的房间移植有一个关键角色。机械学地,和 SR 蛋白质 kinases (SRPK ) 的激活的 hnRNP A1 的导致 EGF 的 ubiquitylation 导致拼接的 Rac1 的 upregulation isoform, Rac1b,支持房间活动性。这些调查结果解开在蛋白质 ubiquitylation 并且在 EGF/EGF 受体发信号的其他的拼接之间的新奇串音,并且在 modulating 房间移植识别新 EGF/SPSB1/hnRNP A1/Rac1 轴,它可以为癌症治疗有重要含意。 | Feng Wang Xing Fu Peng Chen Ping Wu Xiaojuan Fan Na Li Hong Zhu Ting-Ting Jia Hongbin Ji Zefeng Wang Catherine C L Wong Ronggui Hu Jingyi Hui | 2017 | Cell Research2017，27，4： | 5 |
| 2 | Urban traffic flow prediction using a fuzzy- neural approach显示文摘 | Yin Hongbin Wong S C Jianmin Xu and Wong C K | 2002 | Transportation Research Part C: Emerging Technologies2002，10，2： | 1 |
| 3 | Urban traffic flow prediction using a fuzzy-neural approach显示文摘 | Wong S C Xu Jianmin | 2002 | Transportation Research Part C2002，，10： | 1 |
| 4 | Urban Traffic Flow Prediction Using a Fuzzy-neural Approach显示文摘 | Yin Hongbin Wong S C Xu Jianmin | 2002 | Transportation Research Part C2002，，： | 1 |
| 5 | Urban traffic flow prediction using a fuzzy-neural approach显示文摘 | Yin Hongbin Wang S C Xu Jianmin | 2002 | Transportation Research Part C: Emerging Technologies2002，10，2： | 1 |
| 6 | Arbitrage and equilibrium in asset exchange economies:a survey显示文摘 | Hongbin D Guangya C Shouyang W | 2003 | Advanced Modelling and Optimization2003，5，： | 1 |
| 7 | The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies 显示文摘 | Hongbin J Danan L Liang C | 2006 | ancer Cell2006，9，6： | 1 |
| 8 | Urban Traffic Flow Prediction Using a Fuzzy-neural Approach显示文摘 | Yin Hongbin Wang S C Xu Jianmin Wang C K | 2002 | Transportation Research Part C:Emerging Technologies2002，10，2： | 1 |
| 9 | X box-binding protein 1 regulates angiogenesis in human pancreatia adenocarcinomas显示文摘 | LORENZO R R HONGBIN C MARIA P | 2009 | Trans Oncol2009，1，2： | 1 |
| 10 | Research on seamless mobility han- dover for 6LoWPAN wireless sensor networks 显示文摘 | Xiaonan W Hongbin C | 2015 | Telecom- munication Systems2015，61，1： | 1 |
| 11 | Urban traffic flow prediction using a fuzzy-neural approach显示文摘 | Yin Hongbin Wang S C Xu Jianmin Wang C K | 2002 | Transportation Research Part C: Emerging Technologies2002，10，2： | 1 |
| 12 | Effect of ABO blood type on ovarian reserve in Chinese women 显示文摘 | Shengli L Rong L Hongbin C | 2014 | Fertil Steril2014，102，： | 1 |
| 13 | Urban traffic flow prediction using a fuzzy-neural approach显示文摘 | Yin Hongbin Wong S C Xu Jianmin | 2002 | Transportation Research Part C2002，，10： | 1 |
| 14 | Eat, Drink, Firms, Government: An Investigation of Corrup- tion from the Entertainment and Travel Costs of Chinese Firms显示文摘 | Hongbin C Hanming F Colin X | 2011 | Journal of Law and Economics2011，，1： | 1 |
| 15 | Urban traffic flow prediction using a fuzzy-neural approach 显示文摘 | Yin Hongbin Wong S C Xu Jianmin | 2002 | TransportationResearch Part C2002，，10： | 1 |
| 16 | Aerosol properties in a Chinese semiarid region显示文摘 | Xiangao X Hongbin C Pucai W | 2004 | Atmos Env2004，38，27： | 1 |
| 17 | Urban traffic flow prediction using a fuzzy-neural approach 显示文摘 | HONGBIN YIN S C WONG JIANMIN XU | 2002 | Transportation Research Part C2002，，10： | 1 |
| 18 | Graphene oxide : prepa- ration, functionalization, and electrochemical applications 显示文摘 | DA C HONGBIN F JINGHONG L | 2012 | Chemical Reviews2012，112，11： | 1 |
| 19 | Urban traffic flow prediction using a fuzzy-neural approach 显示文摘 | Yin Hongbin Wong S C Xu Jianmin | 2002 | Transportation Research Part C2002，，10： | 1 |
| 20 | Urban traffic flow prediction using a fuzzy-neural approach显示文摘 | YIN HONGBIN WONG S C XU J IANMIN | 2002 | Transportation Research Part C2002，13，8： | 1 |
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