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| 1 | Hepatic steatosis is associated with an increased risk of carotid atherosclerosis显示文摘AIM: Although an association between helatic steatosis and vascular risk factors has been described, direct relationships between fatty liver and atherosclerosis have not yet been investigated. The aim of the present study has been to investigate those relationships.METHODS: The Study of Health in Pomerania examined a random population sample aged between 20 and 79 years.A study population of 4 222 subjects without hepatitis B and C infections and without liver cirrhosis was available for the present analysis. Hepatic steatosis was defined sonographically and intima-media thickness (IMT) as well as plaque prevalence were estimated by carotid ultrasound.RESULTS: The prevalence rate of hepatic steatosis was 29.9%. Among subjects aged ≥45 years, an association between hepatic steatosis and IMT of the carotid arteries was found in bivariate analysis, but not after adjustment for atherosclerotic risk factors. Individuals with fatty liver had more often carotid plaques than persons without fatty liver (plaque prevalence rate 76.8% vs 66.6%; P<0.001).This association persisted after adjustment for confounding factors and was predominantly present in subjects with no to mild alcohol consumption.CONCLUSION: There is an independent association between hepatic steatosis and carotid atherosclerotic plaques. Metabolic changes due to nonalcoholic fatty liver disease may explain this relationship. | Henry V(o|¨)lzke Daniel M.Robinson Volker Kleine Roland Deutscher Wolfgang Hoffmann Jan Lüdemann Ulf Schminke Christof Kessler Ulrich John | 2005 | World Journal of Gastroenterology2005，11，12： | 29 |
| 2 | Food safety management and regulation:International experiences and lessons for China显示文摘China is experiencing rapid urbanization,changes in diets,and modernization of food retailing and production. In this context,food safety can become a greater concern for a variety of reasons. The purpose of this article is to review the international experiences and lessons regarding food safety management,regulation,and consumer behavior,with the goal of identifying how to improve food safety in middle income countries such as China. International experience in addressing food safety provides two general kinds of lessons. First,a middle-income country such as China needs to develop the capacity to carry out risk analysis in order to better focus public resources on the most important risks. Second,it will be important to leverage market incentives so as to make the best use of limited public capacity to enforce standards. International experiences show that food safety management is feasible where market incentives exist,and that public-private partnerships can support the process of improving food safety management. Market incentives require effective consumer or buyer demand,mechanisms to identify and reward quality,and supply chain coordination. Public efforts can be targeted to supporting these market developments for the risks that are the greatest burden to public health. | L Unnevehr V Hoffmann | 2015 | Journal of Integrative Agriculture2015，14，11： | 7 |
| 3 | Biology of Trichogramma ostriniae (Hymenoptera: Trichogrammatidae) reared on Ostriniae nubilalis (Lepidoptera: Pyralidae) and survey for additional hosts显示文摘 | HOFFMANN M P WALKER D L SHELTON A M | 1998 | Entomophaga1998，40，： | 2 |
| 4 | The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation显示文摘 | Hoffmann A Levchenko A Scott M L | 2002 | Science2002，298，5596： | 2 |
| 5 | Abdominal Visceral and Subcutaneous Adipose Tissue Compartments: Association With Metabolic Risk Factors in the Framingham Heart Study显示文摘 | Caroline S. Fox Joseph M. Massaro Udo Hoffmann Karla M. Pou Pal Maurovich-Horvat Chun-Yu Liu Ramachandran S. Vasan Joanne M. Murabito James B. Meigs L Adrienne Cupples Ralph B. D’Agostino Christopher J. O’Donnell | 2007 | Circulation2007，，1： | 2 |
| 6 | A simple and general method for transferring genes into plants显示文摘 | FRY J E HOFFMANN N L | 1985 | Science1985，217，： | 1 |
| 7 | Role of phosphorylation in the conformation of tau peptides implicated in Alzheimer's disease 显示文摘 | DALY N L HOFFMANN R OTVOS L J R | 2000 | Biochemistry2000，39，30： | 1 |
| 8 | Effects of anticaking agents on the thermodynamics and kinetics of water sorption by potash fertilizers 显示文摘 | Hanse L D Hoffmann F Strathdee G | 1998 | Powder Technology1998，，98： | 1 |
| 9 | Delivery of substances into cells and tissues using a particle bombardment process 显示文摘 | Horsch R B Fry J E Hoffmann N L | 1987 | Part Sci Techn1987，5，1： | 1 |
| 10 | MRI study ofhuman brain exposed to weak direct current stimulation of the frontal cortex显示文摘 | Nitsche MA Niehaus L Hoffmann KT | 2004 | ClinNeurophysiol2004，115，10： | 1 |
| 11 | 查看详情显示文摘 | Siegle H Kaczmarczyk G Filippidis L Litvinchuk A P Hoffmann A Thomsen C | | 0，，： | 1 |
| 12 | Effects of monounsaturated fatty acids on glycaemic control in patients with abnormal glucose metabolism: a systematic review and meta-analysis显示文摘 | Schwingshackl L Strasser B Hoffmann G | 2011 | Ann Nutr Metab2011，58，4： | 1 |
| 13 | Adjuvant autologous renal tumour cell vaccine and risk of tumor progression in patients with renal-cell carcinoma after radical nephrectomy:phaseⅢ,randomised controlled trial显示文摘 | Jocham D Richter A Hoffmann L | 2004 | Lancet2004，3639，9409： | 1 |
| 14 | Role of Thalamic Projection in NMDA Receptor-Induced Disruption of Cortical Slow Oscillation and Short-Term Plasticity显示文摘 | Kiss T Hoffmann WE Scott L | 2011 | Front Psychiatry2011，2，： | 1 |
| 15 | A simple and general method for transferring genes into plants, Science显示文摘 | Fry T E Hoffmann N L | 1995 | (227): 1227 - 12311995，，227： | 1 |
| 16 | Genotype and plasma concentration of cystatin C in patients with coronary heart disease and risk for secondary cardiovascular events显示文摘 | Michael L Loem M Hoffmann MM | 2005 | Arterioscler Thromb Vasc Biol2005，25，7： | 1 |
| 17 | A simple and general method for transferring genes into plants 显示文摘 | Horsch R B Fry J E Hoffmann N L | 1985 | Science1985，227，： | 1 |
| 18 | A cationic fluorocarbon surfactant DEFUMAC1 and its mixed systems with cationic surfactants:^19FNMR and surface tension study 显示文摘 | Dong S L Xu G Y Hoffmann H | 2007 | Phys Chem B2007，111，： | 1 |
| 19 | A simple and general method for transferring genes into plants显示文摘 | Horsch R B Fry J E Hoffmann N L | 1985 | Sci- ence1985，227，： | 1 |
| 20 | A simple and general method for transferring genes into plants 显示文摘 | Horsch R B FryJ E Hoffmann N L | 1985 | Science1985，227，： | 1 |
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