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| 1 | Screening and identification of mimotopes of the major shrimp allergen tropomyosin using one-bead-one- compound peptide libraries显示文摘one-bead-one-compound (OBOC ) 组合的肽图书馆是一个强大的工具识别 ligand 和受体相互作用。这里,我们使用了 OBOC 图书馆技术识别对主要贝壳变应原 tropomyosin 的免疫球蛋白 E (IgE ) epitopes 特定的 mimotopes。有 8-12 氨基酸残余的 OBOC 肽图书馆为 tropomyosin 的 IgE mimotopes 与贝壳过敏症从病人与浆液样品被屏蔽。25 mimotopes 从屏蔽被识别,他们到 tropomyosin 特定的 IgE 的有约束力的反应被肽 ELISA 证实。这些 mimotopes 能基于顺序相同被划分成七簇,并且由聚类的 mimotopes 的 EpiSearch 印射的 epitope 被执行描绘并且证实 mimotopes 的有效性。五从六预言的 epitopes 被发现与 tropomyosin 的以前识别的 epitopes 重叠。为了推进,证实 mimotopes 的模仿潜力, BALB/c 老鼠被使免疫, mimotopes 结合了到锁眼恋栈者 hemocyanin 和 assayed 让他们的能力导致 tropomyosin 特定的抗体。那收到的 mimotope 免疫被发现有 tropomyosin 特定的免疫球蛋白 G 的提高的水平的 BALB/c 老鼠,然而并非收到了无关的 mimotope 的老鼠。这研究用整个 sera 开创 OBOC 图书馆的成功的申请屏蔽并且识别多重虾变应原 mimotopes 并且验证他们在 vitro 使用的模仿潜力,在 vivo,并且在 silico 方法。 | Nicki YH Leung Christine YY Wai Marco HK Ho Ruiwu Liu Kit S Lam Jin Jun Wang Shang An Shu Ka Hou Chu Patrick SC Leung | 2017 | Cellular & Molecular Immunology2017，14，3： | 6 |
| 2 | Acquired Fanconi syndromeassociated with prolonged adefovir dipivoxil therapy in achronic hepatitis B patient显示文摘 | Law ST Li KK Ho YY | 2013 | Am J Ther2013，20，6： | 1 |
| 3 | Eleetroacupuneture reduces u- terine after blood flow impedance in infertile women显示文摘 | Ho M Huang LC Chang YY | 2009 | Taiwan J Obstet Gyneeo12009，48，2： | 1 |
| 4 | Natural history of human papillomavirus type 16 virus-like particle antibodies in young women显示文摘 | Ho GY Studentsov YY Blerman R | 2004 | Cancer Epidemiol Biomarkers Prev2004，13，： | 1 |
| 5 | Electroacupunc- ture reduces uterine artery blood flow impedance in in- fertile women显示文摘 | Ho M Huang LC Chang YY | 2009 | Taiwan J Obstet Gynecol2009，48，14： | 1 |
| 6 | Natural history of human papillomavirus type 16 virus-like particle antibodies in young women显示文摘 | Stodentsov YY Bierman R | 2004 | Cancer Epidemiol Biomarkers Prev2004，13，1： | 1 |
| 7 | Natural history of human papillomavirus type 16 virus-like particle antibodies in young women显示文摘 | Ho GY Studentsov YY BIerman R | 2004 | Cancer Epidemiol Biomarkers Prey2004，13，1： | 1 |
| 8 | Natural history of human papillomavirus type 16virus-like particle antibodies in young women显示文摘 | Ho GY Studentsov YY Bierman R | 2004 | Cancer Epidemiol Biomarkers Prev2004，13，1： | 1 |
| 9 | Nephrotoxicity, including acquired Faneoni's syndrome, caused by adefovir dipivoxil - is there a safe dose?显示文摘 | Law ST Li KK Ho YY | 2012 | J Clin Pharm Ther2012，37，2： | 1 |
| 10 | Synovial chondromatosis of the upper extremity 显示文摘 | Ho YY Choueka J | 2013 | J Hand Surg Am2013，38，4： | 1 |
| 11 | Nepbrotoxicity, including acquired Fanconi ' s syndrome, caused by adefovir dipivoxilis there a safe dose 显示文摘 | Law ST Li KK Ho YY | 2012 | J Clin Pharm Ther2012，37，2： | 1 |
| 12 | Acute aortic dissection complicated by acute ischemic stroke: diagnostic challen- ges显示文摘 | Ho CH Chen YL Lin YY | 2012 | Am J Emerg Med2012，30，9： | 1 |
| 13 | Natural history of human papillomavirus type 16 virus-like particle antibodies in young women显示文摘 | Ho GY Studentsov YY BIerman R | 2004 | Cancer Epidemiol Biomarkers Prey2004，13，： | 1 |
| 14 | Effects of a Patient Educational Video Program on Bowel Preparation Prior to Colonoscopy显示文摘 | YY Cho HO Kim | 2015 | Journal of Korean Academy of Nursing2015，45，5： | 1 |
| 15 | Nepbrotoxicity, including acquired Fanconi' s syndrome, caused by adefovir dipivoxilis there a safe dose 显示文摘 | Law ST Li KK Ho YY | 2012 | J Clin Pharm Ther2012，37，2： | 1 |
| 16 | Natural history of human papillomavirus type 16 virus-like particle antibodies in young women 显示文摘 | Ho GY Studentsov YY Blerman R | 2004 | Cancer Epid Biota Prey2004，13，1： | 1 |
| 17 | Com- bined human papillomavirus DNA and human papillo- mavirus-like particle serologic assay to identify women at risk for high-grade cervical intraepithelial neoplasia显示文摘 | Einstein MH Studentsov YY Ho GY | 2007 | Int J Cancer2007，120，1： | 1 |
| 18 | Postural hypotension as the initial presentation of fuhninant right ventricular myocarditis 显示文摘 | Ho CH Wu YC Lin YY | 2010 | Am J Emerg Med2010，28，6： | 1 |
| 19 | Hysteroscopic transcervical resection: a straightforward method corrects bleeding related to cesarean section scar defects 显示文摘 | Shih CL Chang YY Ho M | 2011 | Am J Obstet Gynecol2011，204，： | 1 |
| 20 | Congenitall absent third molars in12 to 16 years old Singaporean Chinese patients: a retrospective radiographic study 显示文摘 | Mok YY Ho KK | 1996 | Ann Acad Med Singapore1996，25，6： | 1 |
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