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| 1 | CABYR binds to AKAP3 and Ropporin in the human sperm fibrous sheath显示文摘钙绑定酷氨酸调整 phosphorylation 的蛋白质(CABYR ) 是高度多态的钙绑定 tyrosine-/threonine-phosphorylated 和 serine-/threonine-phosphorylated 涉及 capacitation 的含纤维的鞘(FS ) 蛋白质。一个通常认为的领域(氨基酸 12 鈥 ? 8 ) 对类型 II 营地依赖者蛋白质 kinase A (RII ) dimerisation 和抛锚 kinase 蛋白质(AKAP ) 的规章的子单元相应在 N 终点的蛋白质 kinase A 的有约束力的领域建议那 CABYR 可以自我装配并且绑在 AKAP。而且,有证据, CABYR 与 AKAP 限制了相互作用。然而,推进在 CABYR 之间的证据和新关系,包括 AKAP,另外的 FS 蛋白质将在理解 FS 的基本生理学是有用的。在这研究,为不可溶解的蛋白质的 co-immunoprecipitation 的新策略,以及在有集体 spectrometry 和西方的污点的联合的标准 co-immunoprecipitation 方法,被采用探索在 CABYR, AKAP3 和 Ropporin 之间的关系。结果证明 AKAP3 是有由 anti-CABYR-A polyclonal 抗体的 CABYR 的 co-immunoprecipitated,并且,相反地, CABYR 也是有由 anti-AKAP3 polyclonal 抗体的 AKAP3 的 co-immunoprecipitated。包含蛋白质的另一象 RII 一样域, Ropporin,也是有 CABYR 的 co-immunoprecipitated,显示 Ropporin 是 CABYR 的绑定之一合伙。在 CABYR, AKAP3 和 Ropporin 之间的相互作用被酵母证实二混血儿的试金。进一步的分析显示出那 CABYR 不仅由它的 RII 领域绑在 AKAP3 而且除象 RII 一样领域以外通过另外的区域绑在 Ropporin。这是 CABYR 变体形成的第一示范不仅有 scaffolding 蛋白质 AKAP3 而且与在人的精子 FS 的另一象 RII 一样包含域的蛋白质的建筑群。 | Yan-Feng Li Wei He Arabinda Mandal Young-Hwan Kim Laura Digilio Ken Klotz Charles J Flickinger John C Herr | 2011 | Asian Journal of Andrology2011，13，2： | 5 |
| 2 | Long-term follow-up study of gastroduodenal lesions after radioembolization of hepatic tumors显示文摘AIM:To evaluate the long-term natural history of the gastroduodenal lesions secondary to extrahepatic embolization with Ytrium 90(90 Y) spheres.METHODS:From September 2003 to January 2012,379 procedures of liver radioembolization(RE) using resin microspheres loaded with 90 Y were performed in our center.We have retrospectively compiled the data from 379 RE procedures performed in our center.We report a comprehensive clinical,analytical,endoscopic and histologic long-term follow-up of a series of patients who developed gastroduodenal lesions after the treatment.RESULTS:Six patients(1.5%) developed gastrointestinal symptoms and had gastrointestinal lesions as shown by upper endoscopy in the next 12 wk after RE.The mean time between RE and the appearance of symptoms was 5 wk.Only one patient required endoscopic and surgical treatment.The incidence of gastrointestinal ulcerations was 3.75%(3/80) when only planar images were used for the pre-treatment evaluation.It was reduced to 1%(3/299) when singlephoton emission computed tomography(SPECT) images were also performed.The symptoms that lasted for a longer time were nausea and vomiting,until 25 mo after the treatment.CONCLUSION:All patients were free from severe symptoms at the end of follow-up.The routine use of SPECT has decreased the incidence of gastrointestinal lesions due to unintended deployment of 90 Y particles. | Iago Rodríguez-Lago Cristina Carretero Maite Herráiz José C Subtil Maite Betés Macarena Rodríguez-Fraile Jesús J Sola José I Bilbao Miguel Muoz-Navas Bruno Sangro | 2013 | World Journal of Gastroenterology2013，19，19： | 2 |
| 3 | Two-dimensionalgel electrophoretie analysis of vectorially labeled surface proteins of human spermatozoa 显示文摘 | Naaby Hansen S Flickinger C J Herr J C | 1997 | Biol Reprod1997，56，3： | 1 |
| 4 | Evaluation of the Faces Pain Scale for use with the elderly显示文摘 | Herr KA Mobily PR Kohout F J | 1998 | Clin J Pain1998，14，： | 1 |
| 5 | Implementing matching estimators for average treatment effects in Stata显示文摘 | Abadie A Drukker D Herr J L Imbens G W | | 0，，03： | 1 |
| 6 | Etiology of Rhizoctonia cerealis in sharp eyespot of wheat显示文摘 | Lipps P E Herr L J | 1982 | Phytopathology1982，72，： | 1 |
| 7 | Ion-gated electron transfer in self-assembled monolayer films 显示文摘 | Campbell D J Herr B R Hulteen J C | 1996 | J Am Chem Soc1996，118，10： | 1 |
| 8 | Effects of word-of-mouth and product-attribute information on persuasion:An accessibility-diagnosticity perspective显示文摘 | Herr P.M Kardes F.R Kim J | | 0，，04： | 1 |
| 9 | Optimizing outcomes at every stage of bladder cancer: do we practice it? 显示文摘 | HERR H KONETY B STEIN J | 2009 | UrolOncol2009，27，1： | 1 |
| 10 | Field trial to evaluate immunogenicity of a glycoprotein I (gE) - deleted pseudorabies virus vaccine after its administration in the presence ofmaternal antibodies显示文摘 | Weigel R M Lehman J R Herr L Hahn E C | 1995 | Am J Vet Res1995，56，9： | 1 |
| 11 | Evaluation of the revised faces pain scale, verbal descriptor sclae, numeric rating scale, and iowa pain thermometer in older minority adults显示文摘 | WARE L J EPPS C D HERR K | 2006 | Pain Manag Nurs2006，7，： | 1 |
| 12 | Etiology of Rhizoctonia cerealis in sharp eye spot of wheat显示文摘 | Lipps P E Herr L J | 1982 | Phytopathology1982，72，： | 1 |
| 13 | Predictive val- ues of lacunar transient ischemic attacks 显示文摘 | Herre D Gautier-Bertrand M Labreuche J | 2004 | Stroke2004，35，6： | 1 |
| 14 | Anatomical structures in the maxillary sinus related to lateral sinus elevation: a cone beam computed tomographic analysis显示文摘 | KANG S J SHIN S I HERR Y | 2011 | Clin Oral Implants Res2011，，： | 1 |
| 15 | Intratympanic Steroid Perfusion for Refractory Sudden Sensorineural Hearing Loss显示文摘 | Herr B D Marzo S J | 2005 | Otolaryngol Head Neck Surg2005，132，4： | 1 |
| 16 | Physicians Appeals on the Dangers of Mobile Communication-what is the Evidence? Assessment of Public Health Data显示文摘 | Nieden A Z Dietz C Eikmann T Kiefer J Herr C E W | 2009 | International Journal of Hygiene and Environmental Health2009，，212： | 1 |
| 17 | Model calcula- tions of total maximum daily loads of mercury for drainage lakes显示文摘 | CHEN C W HERR J W GOLDSTEIN R A | 2008 | Journal of the American Water Resources Associa- tion2008，44，5： | 1 |
| 18 | Effects of Word - of - mouth and Product- attribute Information on Persuasion: An Aecessibihty- di- agnosticity Perspective 显示文摘 | Herr P M Kardes F R Kim J | 1991 | Journal of Consumer Research1991，17，4： | 1 |
| 19 | Asymmetrical 3-dof spherical parallel mechanisms显示文摘 | Karouia M Herr J M | 2005 | European Journal of Mechanics A/Solids2005，24，1： | 1 |
| 20 | Etiology of Rhizoctonia cerealis in sharp eyespot of wheat显示文摘 | Lipps P E Herr L J | 1982 | Phytopathology1982，72，： | 1 |
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