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| 1 | An all-organic Composite Actuator Material with High Dielectric Constant显示文摘 | Zhang Q M Hengfeng Li Martin Poh | 2002 | Nature2002，419，： | 1 |
| 2 | Synthesis and characterization of novel fluorinated bistolane-type liquid crystals显示文摘 | Kegang Liu Hengfeng Li Kan Wang | 2001 | Liquid Crystals2001，28，： | 1 |
| 3 | Performance and microbial response during the fast reactivation of Anammox system by hydrodynamic stress control显示文摘Anaerobic ammonium oxidation(Anammox)has become a promising method for biological nitrogen removal.However,this biotechnology application is always limited due to the low growth rate and biomass yield of Anammox bacteria.This study investigated the process of fast reactivation of an Anammox consortium idled for 2 years via hydrodynamic stress control.The results showed that the Anammox system was efficiently and quickly reactivated by shortening of the hydraulic retention time(HRT)of the reactor from 12 to6 hr within 68 days of operation.Moreover,at a 4-hr HRT with an influent total nitrogen loading rate of 1.2 kg N/(m3·day),the reactor maintained high biological performance with an ammonium removal loading rate of 0.52 kg N/(m3·day)and a nitrite removal rate of0.59 kg N/(m3·day).In the reactivated Anammox reaction,the stoichiometric coefficients of NH4+–N to NO2-–N and NH4+–N to NO3-–N were 1:1.04±0.08 and 1:0.31±0.03,respectively.The specific Anammox activity and hydrazine oxidoreductase activity,both of which represent the degree of Anammox bacteria present,increased as the hydrodynamic stress increased and were maximally(125.38±3.01 mg N/(g VSS·day)and 339.42±6.83μmol/(min·g VSS),respectively)at 4-hr HRT.Microbial response analysis showed that the dominant microbial community was obviously shifted and the dominance of Anammox bacteria was enhanced during the hydrodynamic selection. | Yuan Li Zhenxing Huang Wenquan Ruan Hongyan Ren Hengfeng Miao | 2014 | Journal of Environmental Sciences2014，26，9： | 1 |
| 4 | An all-organic composite actuator material with a high dielectric constant 显示文摘 | Zhang Qiming Li Hengfeng Poh M | 2002 | Nature2002，419，： | 1 |
| 5 | An allorganic composite actuator material with a high di electric constant显示文摘 | Zhang Qiming Li Hengfeng Poh M | 2002 | Nature2002，419，19： | 1 |
| 6 | Acellular nerve grafts supplemented with induced pluripotent stem cell-derived exosomes promote peripheral nerve reconstruction and motor function recovery显示文摘Peripheral nerve injury is a great challenge in clinical work due to the restricted repair gap and weak regrowth ability.Herein,we selected induced pluripotent stem cells(iPSCs)derived exosomes to supplement acellular nerve grafts(ANGs)with the aim of restoring long-distance peripheral nerve defects.Human fibroblasts were reprogrammed into iPSCs through non-integrating transduction of Oct3/4,Sox2,Klf4,and c-Myc.The obtained iPSCs had highly active alkaline phosphatase expression and expressed Oct4,SSEA4,Nanog,Sox2,which also differentiated into all three germ layers in vivo and differentiated into mature peripheral neurons and Schwann cells(SCs)in vitro.After isolation and biological characteristics of iPSCs-derived exosomes,we found that numerous PKH26-labeled exosomes were internalized inside SCs through endocytotic pathway and exhibited a proliferative effect on SCs that were involved in the process of axonal regeneration and remyelination.After that,we prepared ANGs via optimized chemical extracted process to bridge 15 mm long-distance peripheral nerve gaps in rats.Owing to the promotion of iPSCs-derived exosomes,satisfactory regenerative outcomes were achieved including gait behavior analysis,electrophysiological assessment,and morphological analysis of regenerated nerves.Especially,motor function was restored with comparable to those achieved with nerve autografts and there were no significant differences in the fiber diameter and area of reinnervated muscle fibers.Taken together,our combined use of iPSCs-derived exosomes with ANGs demonstrates good promise to restore long-distance peripheral nerve defects,and thus represents a cell-free strategy for future clinical applications. | Jianfeng Pan Meng Zhao Xiangjiao Yi Jianguo Tao Shaobo Li Zengxin Jiang Biao Cheng Hengfeng Yuan Feng Zhang | 2022 | Bioactive Materials2022，7，9： | 1 |
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