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| 1 | Grain refinement of Mg-Al alloys inoculated by MgAl_(2)O_(4)powder显示文摘As a potent nucleating substrate forα-Mg grain,MgAl_(2)O_(4) powder was used to inoculate the Mg-Al melt in this study.The effects of MgAl_(2)O_(4)amount,holding time and Al content on the grain size and grain refining ratio of the inoculated Mg-Al alloys are systematically investigated.The results show that the minimum grain size of Mg-3Al alloy is achieved by adding 2wt.%MgAl_(2)O_(4)powder and this alloy exhibits higher grain refining ratio than Mg-5Al and Mg-8Al alloys.The crystallographic misfit calculation indicates the wellmatching and possible orientation relationships(ORs)betweenα-Mg and MgAl_(2)O_(4).Among these predicted ORs,[10–10]α−Mg//[110]MgAl2O4 in(0002)α−Mg//(1–13)MgAl2O4 possesses the smallest misfit,i.e.,2.34%(fr).Both results of the experiment and crystallographic calculation demonstrate that the grain refinement of Mg-Al alloys is attributed to the MgAl_(2)O_(4)particles acting as the heterogeneous nucleation substrates forα-Mg grains. | Hengbin Liao Meiyan Zhan Chengbo Li Zhiqiang Ma Jun Du | 2021 | Journal of Magnesium and Alloys2021，9，4： | 7 |
| 2 | Molecular basis underlying rice tiller angle:Current progress and future perspectives显示文摘Crop plant architecture is an important agronomic trait that contributes greatly to crop yield.Tiller angle is one of the most critical components that determine crop plant architecture,which in turn substantially af-fects grain yield mainly owing to its large influence on plant density.Gravity is a fundamental physical force that acts on all organisms on earth.Plant organs sense gravity to control their growth orientation,including tiller angle in rice(Oryza sativa).This review summarizes recent research advances made using rice tiller angle as a research model,providing insights into domestication of rice tiller angle,genetic regulation of rice tiller angle,and shoot gravitropism.Finally,we propose that current discoveries in rice can shed light on shoot gravitropism and improvement of plant tiller/branch angle in other species,thereby contributing to agricultural production in the future. | Wenguang Wang Hengbin Gao Yan Liang Jiayang Li Yonghong Wang | 2022 | Molecular Plant2022，15，1： | 5 |
| 3 | Synergistic refining mechanism of Mg-3%Al alloy refining by carbon inoculation combining with Ca addition显示文摘Mg-3%Al alloy was refined by carbon inoculation combining with 0.2%Ca addition.High grain refining efficiency was obtained and the synergistic refining mechanism was deeply discussed in the present study.Al-C-O particles,actually Al4C3 particles,were formed in the carbon-inoculated Mg-3%A1 alloy acting as nuclei forα-Mg grains.Ca addition had no obvious effect on size distribution of the nucleating particles.Ca segregation was proved on Al4C3 particles,which should reduce the interfacial energy of nuclei/Mg.The constitutional undercooling in front of nucleus/liquid was increased from 0.12℃to 0.15℃induced by 0.2%Ca addition.The synergistic grain refining efficiency can be attributed to the higher constitutional undercooling and lower the interface energy of nucleus/Mg induced by Ca addition.More nucleating particles with small size could be activated acting as potent nuclei ofα-Mg grains.Consequently,Mg-3%Al alloy could be effectively refined due to the synergistic effect induced by carbon inoculation combining with Ca. | Chengbo Li Shuqing Yang Jun Du HengBin Liao Gan Luo | 2020 | Journal of Magnesium and Alloys2020，8，4： | 3 |
| 4 | Enhancing rice grain production by manipulating the naturally evolved cis-regulatory element-containing inverted repeat sequence of OsREM20显示文摘Grain number per panicle(GNP)is an important agronomic trait that contributes to rice grain yield.Despite its importance in rice breeding,the molecular mechanism underlying GNP regulation remains largely unknown.In this study,we identified a previously unrecognized regulatory gene that controls GNP in rice,Oryza sativa REPRODUCTIVE MERISTEM 20(OsREM20),which encodes a B3 domain transcription factor.Through genetic analysis and transgenic validation we found that genetic variation in the CArG box-containing inverted repeat(IR)sequence of the OsREM20 promoter alters its expression level and contributes to GNP variation among rice varieties.Furthermore,we revealed that the IR sequence regulates OsREM20 expression by affecting the direct binding of OsMADS34 to the CArG box within the IR sequence.Interestingly,the divergent pOsREM20IR and pOsREM20ΔIR alleles were found to originate from different Oryza rufipogon accessions,and were independently inherited into the japonica and indica subspecies,respectively,during domestication.Importantly,we demonstrated that IR sequence variations in the OsREM20 promoter can be utilized for germplasm improvement through either genome editing or traditional breeding.Taken together,our study characterizes novel genetic variations responsible for GNP diversity in rice,reveals the underlying molecular mechanism in the regulation of agronomically important gene expression,and provides a promising strategy for improving rice production by manipulating the cis-regulatory element-containing IR sequence. | Xiaowei Wu Yan Liang Hengbin Gao Jiyao Wang Yan Zhao Lekai Hua Yundong Yuan Ahong Wang Xiaohui Zhang Jiafan Liu Jie Zhou Xiangbing Meng Dahan Zhang Shaoyang Lin Xuehui Huang Bin Han Jiayang Li Yonghong Wang | 2021 | Molecular Plant2021，14，6： | 3 |
| 5 | Ked analysis for the impulse variable speed device and its real motion law显示文摘 | DU Li REN Hengbin XU Yuan | 2004 | Chinese Journal of Mechanical Engineering2004，17，： | 1 |
| 6 | Programmable deaminase-free base editors for G-to-Y conversion by engineered glycosylase显示文摘Current DNA base editors contain nuclease and DNA deaminase that enables deamination of cytosine(C)or adenine(A),but no method for guanine(G)or thymine(T)editing is available at present.Here we developed a deaminase-free glycosylase-based guanine base editor(gGBE)with G editing ability,by fusing Cas9 nickase with engineered N-methylpurine DNA glycosylase protein(MPG).By several rounds of MPG mutagenesis via unbiased and rational screening using an intron-split EGFP reporter,we demonstrated that gGBE with engineered MPG could increase G editing efficiency by more than 1500 fold.Furthermore,this gGBE exhibited high base editing efficiency(up to 81.2%)and high G-to-T or G-to-C(i.e.G-to-Y)conversion ratio(up to 0.95)in both cultured human cells and mouse embryos.Thus,we have provided a proof-of-concept of a new base editing approach by endowing the engineered DNA glycosylase the capability to selectively excise a new type of substrate. | Huawei Tong Nana Liu Yinghui Wei Yingsi Zhou Yun Li Danni Wu Ming Jin Shuna Cui Hengbin Li Guoling Li Jingxing Zhou Yuan Yuan Hainan Zhang Linyu Shi Xuan Yao Hui Yang | 2023 | National Science Review2023，10，8： | 1 |
| 7 | Resistance Identification of Different Flue-cured Tobacco Varieties against Black Shank显示文摘The resistance of 15 flue-cured tobacco varieties were identified by artificial inoculation of black shank. The results showed that K326,Yunyan 202 and NC102 belonged to resistance variety against black shank,and the resistance successively were K326 > Yunyan 202 > NC102; Yunyan 87,Cuibi 5,Yunyan 85,Yunyan 97 and Cuibi 7 belonged to moderate resistance variety against black shank,and the resistance successively were Yunyan 87 > Cuibi 5 > Yunyan 85 >Yunyan 97 > Cuibi 7; Cuibi 12,NC82,PVH06 and Cuibi 14 belonged to moderate susceptible variety against black shank,and the resistance successively were Cuibi 12 > NC82 > PVH06 > Cuibi 14; Cuibi 1 and Hongda belonged to high susceptible variety against black shank,and the resistance successively were Cuibi1 > 09011 > Hongda. The disease dynamics of flue-cured tobacco varieties were positively correlated with variety susceptibility,namely the earlier infection in susceptible variety,the faster the disease progression. | Peng Shicheng Yang Peng Zheng Li Cai Hengbin Guan Yu | 2015 | Plant Diseases and Pests2015，6，4： | 1 |
| 8 | Purification and Functional Characterization of SET8, a Nucleosomal Histone H4-Lysine 20-Specific Methyltransferase显示文摘 | Jia Fang Qin Feng Carrie S. Ketel Hengbin Wang Ru Cao Li Xia Hediye Erdjument-Bromage Paul Tempst Jeffrey A. Simon Yi Zhang | 2002 | Current Biology2002，，13： | 1 |
| 9 | An engineered xCas12i with high activity,high specificity,and broad PAM range显示文摘Dear Editor,The clustered regularly interspaced short palindromic repeats-Cas(CRISPR-Cas)systems,including type II Cas9 and type V Cas12 systems,which serve in the adaptive immunity of prokaryotes against viruses,have been developed into genome-editing tools(Anzalone et al.,2020;Doudna,2020).Compared with type II systems,the type V systems including V-A to V-K showed more functional diversity(Yan et al.,2019).Amongst them,Cas12i has a relatively smaller size(1,033-1,093 aa),compared to SpCas9 and Cas12a,and has a 5'-TTN protospacer adjacent motif(PAM)preference(Yan et al.,2019). | Hainan Zhang Xiangfeng Kong Mingxing Xue Jing Hu Zikang Wang Yinghui Wei Haoqiang Wang Jingxing Zhou Weihong Zhang Mengqiu Xu Xiaowen Shen Fengcai Yin Zhiyuan Ai Guangyan Huang Junhui Xia Xueqiong Song Hengbin Li Yuan Yuan Jinhui Li Na Zhong Meiling Zhang Yingsi Zhou Hui Yang | 2023 | Protein & Cell2023，14，7： | 0 |
| 10 | OsHYPK-mediated protein N-terminal acetylation coordinates plant development and abiotic stress responses in rice显示文摘N-terminal acetylation is one of the most common protein modifications in eukaryotes,and approximately 40%of human and plant proteomes are acetylated by ribosome-associated N-terminal acetyltransferase A(NatA)in a co-translational manner.However,the in vivo regulatory mechanism of NatA and the global impact of NatA-mediated N-terminal acetylation on protein fate remain unclear.Here,we identify Huntingtin Yeast partner K(HYPK),an evolutionarily conserved chaperone-like protein,as a positive regulator of NatA activity in rice.We found that loss of OsHYPK function leads to developmental defects in rice plant architecture but increased resistance to abiotic stresses,attributable to perturbation of the N-terminal acetylome and accelerated global protein turnover.Furthermore,we demonstrated that OsHYPK is also a substrate of NatA and that N-terminal acetylation of OsHYPK promotes its own degradation,probably through the Ac/N-degron pathway,which could be induced by abiotic stresses.Taken together,our findings suggest that the OsHYPK-NatA complex plays a critical role in coordinating plant development and stress responses by dynamically regulating NatA-mediated N-terminal acetylation and global protein turnover,which are essential for maintaining adaptive phenotypic plasticity in rice. | Xiaodi Gong Yaqian Huang Yan Liang Yundong Yuan Yuhao Liu Tongwen Han Shujia Li Hengbin Gao Bo Lv Xiahe Huang Eric Linster Yingchun Wang Markus Wirtz Yonghong Wang | 2022 | Molecular Plant2022，15，4： | 0 |
| 11 | Controllable thermal rectification design for buildings based on phase change composites显示文摘Phase-change material(PCM)is widely used in thermal management due to their unique thermal behavior.However,related research in thermal rectifier is mainly focused on exploring the principles at the fundamental device level,which results in a gap to real applications.Here,we propose a controllable thermal rectification design towards building applications through the direct adhesion of composite thermal rectification material(TRM)based on PCM and reduced graphene oxide(rGO)aerogel to ordinary concrete walls(CWs).The design is evaluated in detail by combining experiments and finite element analysis.It is found that,TRM can regulate the temperature difference on both sides of the TRM/CWs system by thermal rectification.The difference in two directions reaches to 13.8 K at the heat flow of 80 W/m^(2).In addition,the larger the change of thermal conductivity before and after phase change of TRM is,the more effective it is for regulating temperature difference in two directions.The stated technology has a wide range of applications for the thermal energy control in buildings with specific temperature requirements. | Hengbin Ding Xiaoshi Li Tianhang Li Xiaoyong Zhao He Tian | 2024 | Journal of Semiconductors2024，45，2： | 0 |
| 12 | Dual-band dynamic reconfigurable intelligent surface for signal enhancement in millimeter wave显示文摘Millimeter wave with large bandwidth,high transmission rate,and low delay is considered a reliable alternative to cope with the spectrum shortage.However,the fast attenuation and narrow beam characteristics make it difficult to achieve long-distance or wide-range applications.Here,a 1-bit dual-band reflective reconfigurable intelligent surface(RIS)for signal enhancement in millimeter wave with 16×16 elements is designed,fabricated,and measured.Different from most existent RIS,dynamic programming is realized at two separate frequency bands by integrating the PIN diodes and field-programmable gate array(FPGA).Particularly,the beam deflection,dual-beam,and multi-beam are created based on the coding theory and convolution operation,proving the effectiveness of wavefront manipulation.Moreover,the far-field patterns and signal power with different coding sequences are measured and compared.It is indicated that the received signal power is 6–7 dB stronger than that without coding,which shows good agreement with the desired expectations.The proposed reconfigurable metasurface exhibits great potential in beam forming,making it a promising candidate for progressive wireless communication applications. | YAO HuiMing DU XinRun WANG HengBin GAO Song PANG YaChen ZHENG HaiRong GONG HuiWen LI Yi XU JianChun ZHANG JianHua BI Ke | 2024 | Science China(Technological Sciences)2024，67，4： | 0 |
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