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| 1 | Forecasting and trading cryptocurrencies with machine learning under changing market conditions显示文摘This study examines the predictability of three major cryptocurrencies—bitcoin,ethereum,and litecoin—and the profitability of trading strategies devised upon machine learning techniques(e.g.,linear models,random forests,and support vector machines).The models are validated in a period characterized by unprecedented turmoil and tested in a period of bear markets,allowing the assessment of whether the predictions are good even when the market direction changes between the validation and test periods.The classification and regression methods use attributes from trading and network activity for the period from August 15,2015 to March 03,2019,with the test sample beginning on April 13,2018.For the test period,five out of 18 individual models have success rates of less than 50%.The trading strategies are built on model assembling.The ensemble assuming that five models produce identical signals(Ensemble 5)achieves the best performance for ethereum and litecoin,with annualized Sharpe ratios of 80.17%and 91.35%and annualized returns(after proportional round-trip trading costs of 0.5%)of 9.62%and 5.73%,respectively.These positive results support the claim that machine learning provides robust techniques for exploring the predictability of cryptocurrencies and for devising profitable trading strategies in these markets,even under adverse market conditions. | Helder Sebastiao Pedro Godinho | 2021 | Financial Innovation2021，7，1： | 21 |
| 2 | 基于激光雷达的移动机器人实时位姿估计方法研究显示文摘位姿估计是移动机器人研究中的一个关键问题,对于运动目标跟踪、机器人导航、地图生成等具有重要意义.提出了一种基于二维激光雷达的实时位姿估计方法,包括基于Hough变换的切线角度直方图算法和迭代切线加权最近点算法两部分.两种算法的结合和切线信息的引入,有效地解决了传统方法无法解决的局部最小值、类孔径、大计算量等问题.仿真数据和室外环境实际数据的大量实验结果表明它具有精度高、速度快、适用性广和对噪声、遮挡和类孔径问题鲁棒性高的特点. | 杨明 董斌 王宏 张钹 Helder Araújo | 2004 | 自动化学报2004，30，5： | 11 |
| 3 | A prospective cancer chemo-immunotherapy approach mediated by synergistic CD326 targeted porous silicon nanovectors显示文摘经由 nanoparticulate 系统的联合治疗已经为癌症治疗作为一条 synergistic 途径被建议了。此处, undecylenic 酸热地修改了多孔的硅 nanoparticles (UnTHCPSi NP ) 与 sorafenib 装载了的 hydrocarbonized,有 anti-CD326 抗体(Ab ) 的 surface-biofunctionalized 在 MCF-7 和 MDA-MB-231 乳癌房间为癌症 chemo 免疫疗法被开发。cytocompatibility 学习没在比 200 g 低的集中为赤裸、结合抗体的 UnTHCPSi (Un-Ab ) NP 显示出重要毒性 ? 浩汰楹杮愠搠 ' 糖锚?湩琠敨漠潸桰汩捩瑩 ? 景琠敨猠牵慦散倠 ? 瑡浯吗? | Mohammad-Ali Shahbazi Neha Shrestha Ermei Makila Francisca Araujo Alexandra Correia Tomas Ramos Bruno Sarmento Jarno Salonen Jouni Hirvonen Helder A. Santos | 2015 | Nano Research2015，8，5： | 2 |
| 4 | Summary of current radiometric calibration coefficients for Landsat MSS, TM, ETM+, and EO-1 ALI sensors显示文摘 | Gyanesh Chander Brian L. Markham Dennis L. Helder | 2009 | Remote Sensing of Environment2009，，5： | 2 |
| 5 | 飞机和直升机结构用苯并恶嗪组分制备工艺显示文摘纤维增强聚合物复合材料正逐渐被视为可取代金属材料来做飞行器和直升飞机组件的耐高温材料。在制备这种复合物的时候,可用树脂的选择是非常有限的,为了开发一种节能、非高压低真空、易实现的制备过程,Henkel和Quickstep研究了一种在室温下储存,容易制备的乐泰苯并恶嗪树脂(Loctite),这种树脂具有高的玻璃化转变温度和出色的热湿性能。 | Helder Barros Abreu Amol Ogale 李进松 管佳明 | 2015 | 航空制造技术2015，58，14： | 2 |
| 6 | Role of dynamic computed tomography scans in patients with congenital craniovertebral junction malformations显示文摘AIM To evaluate the role of dynamic computed tomography(CT)scan imaging in diagnosing craniovertebral junction(CVJ)instability in patients with congenital CVJ malformations.METHODS Patients with symptomatic congenital CVJ malformations who underwent posterior fossa decompression and had a preoperative dynamic CT scan in flexion and extended position were included in this study.Measurements of the following craniometrical parameters were taken in flexed and extended neck position:Atlanto-dental interval(ADI),distance of the odontoid tip to the Chamberlain’s line,and the clivus-canal angle(CCA).Assessment of the facet joints congruence was also performed in both positions.Comparison of the values obtained in flexion and extension were compared using a paired Student’s t-test.RESULTS A total of ten patients with a mean age of 37.9 years were included.In flexion imaging,the mean ADI was1.76 mm,the mean CCA was 125.4°and the mean distance of the odontoid tip to the Chamberlain’s line was+9.62 mm.In extension,the mean ADI was1.46 mm(P=0.29),the mean CCA was 142.2°(P<0.01)and the mean distance of the odontoid tip to the Chamberlain’s line was+7.11 mm(P<0.05).Four patients(40%)had facetary subluxation demonstrated in dynamic imaging,two of them with mobile subluxation(both underwent CVJ fixation).The other two patients with a fixed subluxation were not initially fixed.One patient with atlantoaxial assimilation and C23 fusion without initial facet subluxation developed a latter CVJ instability diagnosed with a dynamic CT scan.Patients with basilar invagination had a lower CCA variation compared to the whole group.CONCLUSION Craniometrical parameters,as well as the visualization of the facets location,may change significantly according to the neck position.Dynamic imaging can provide additional useful information to the diagnosis of CVJ instability.Future studies addressing the relationship between craniometrical changes and neck position are necessary. | Otávio Turolo da Silva Enrico Ghizoni Helder Tedeschi Andrei Fernandes Joaquim | 2017 | World Journal of Orthopedics2017，8，3： | 2 |
| 7 | Repair, regenerative and supportive therapies of the annulus fibrosus: achievements and challenges 显示文摘 | Bron Jl Helder MN Meisel HJ | 2009 | Eur Spine J2009，18，： | 1 |
| 8 | IKONOS geometric characterization显示文摘 | Dennis Helder | 2003 | Remote Sensing of Environment2003，88，2003： | 1 |
| 9 | Numerical analysis of the street canyon thermal conductance to improve urban design and climate显示文摘 | MARTA J N HELDER J P PAULO M C | 2009 | Building and Environment2009，44，1： | 1 |
| 10 | machinery for artificial emotions显示文摘 | LuiS Miguel Botelho Helder Coelho | | Cybernetics And Systems: An International Journal0，2001，： | 1 |
| 11 | Oxygen pore water profiles in continental shelf sediments of the North Sea:turbulent versus molecular diffusion显示文摘 | Lohse L Epping E H G Helder W | | 0，，： | 1 |
| 12 | Landsat-4/5 band 6 relative radiometry 显示文摘 | Gyanesh Chander Dennis L Helder Wayne C Boncyk | 2002 | IEEE Transactions on Geoscience and Remote Sensing2002，40，1： | 1 |
| 13 | Activated carbons treated with sulphuric acid : Catalystsfor catalytic wet peroxide oxidation显示文摘 | Gomes Helder T Miranda Sandra M Sampaio Maria J etal | 2010 | Catal Today2010，151，12： | 1 |
| 14 | Telomerase and Telomeres: From Basic Biology to Cancer Treatment显示文摘 | Marco N. Helder G. Bea A. Wisman Ate G. J. van der Zee | 2002 | Cancer Investigation2002，，1： | 1 |
| 15 | Using conditional copula to estimate value at risk显示文摘 | Helder P P Luiz K H | 2006 | Joumal of Data Science2006，4，1： | 1 |
| 16 | Estuarine nitrite maxima and nitrifying bacteria (Ems-Doallard estuary)显示文摘 | Helder M N de Vries E G | 1983 | Neth J Sea Res1983，17，： | 1 |
| 17 | Cross Cali- bration of the Landsat - 7 ETM+ and EO - 1 ALI Sensor显示文摘 | Chander G Meyer D J Helder D L | 2004 | IEEE Transactions on Geoscience and Remote Sensing2004，42，12： | 1 |
| 18 | Synthesis of poly by ring opening polymerization 显示文摘 | Janneke Helder Frits E Kohn Jan Feijen | 1985 | Makromol Chem Rapid Commun1985，6，1： | 1 |
| 19 | Summary of Current Radiometric Calibration Coefficients for Landsat MSS, TM, ETM+, and EO-1 ALI Sensors显示文摘 | CHANDER G MARKHAM B L HELDER D L | 2009 | Remote Sensing of Environment2009，113，5： | 1 |
| 20 | Adjacent segment degeneration: observations in a goat spinal fusion study 显示文摘 | I-Ioogendoorn R J Helder MN Wuisman PI | 2008 | Spine ( Phila Pa 1976)2008，33，12： | 1 |
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