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| 1 | Ischemic preconditioning-induced hyperperfusion correlates with hepatoprotection after liver resection显示文摘AIM:To characterize the impact of the Pringle ma-neuver (PM) and ischemic preconditioning (IP) on total blood supply to the liver following hepatectomies. METHODS: Sixty one consecutive patients who un-derwent hepatic resection under in flow occlusion were randomized either to receive PM alone (n = 31) or IP (10 min of ischemia followed by 10 min of reperfusion) prior to PM (n = 30). Quantification of liver perfusion was measured by Doppler probes at the hepatic artery and portal vein at various time points after reperfusion of remnant livers. RESULTS: Occlusion times of 33 ± 12 min (mean ± SD) and 34 ± 14 min and the extent of resected liver tissue (2.7 segments) were similar in both groups. In controls (PM), on reperfusion of liver remnants for 15 min, portal perfusion markedly decreased by 29% while there was a slight increase of 8% in the arterial blood flow. In contrast, following IP + PM the portal vein flow remained unchanged during reperfusion and a significantly increased arterial blood flow (+56% vs baseline) was observed. In accordance with a better postischemic blood supply of the liver, hepatocellular injury, as measured by alanine aminotransferase (ALT) levels on day 1 was considerably lower in group B compared to group A (247 ± 210 U/I vs 550 ± 650 U/I, P < 0.05). Additionally, ALT levels were significantly correlated to the hepatic artery in flow.CONCLUSION: IP prevents postischemic flow reduction of the portal vein and simultaneously increases arterial perfusion, suggesting that improved hepatic macrocirculation is a protective mechanism following hepatectomy. | Oleg Heizmann Georgios Meimarakis Andreas Volk Daniel Matz Daniel Oertli Rolf J Schauer | 2010 | World Journal of Gastroenterology2010，16，15： | 12 |
| 2 | COMPARISONS AMONG THE SOLUTIONS OF FIBER TEXTURE VECTOR显示文摘COMPARISONSAMONGTHESOLUTIONSOFFIBERTEXTUREVECTORWANGYandong,A.VadonandJ.J.Heizmann(LMPC/ISGMP,UniversitedeMetz,F-57045MetzCED... | WANG Yandong, A. Vadon and J.J. Heizmann(LMPC/ISGMP, Universite de Metz, F-57045 Metz CEDEX 01, France)ZUO Liang(Department of Materials Science and Engineering, Northeastern University, Shenyang 110006, China) | 1996 | Acta Metallurgica Sinica(English Letters)1996，9，3： | 5 |
| 3 | Annular pancreas associated with duodenal carcinoma显示文摘Annular pancreas (AP) is a rare congenital anomaly. Coexisting malignancy has been reported only in a few cases. We report what is, to the best of our knowledge, the first case in the English literature of duodenal adenocarcinoma in a patient with AP. In a 55-year old woman with duodenal outlet stenosis magnetic resonance cholangiopancreatography showed an aberrant pancreatic duct encircling the duodenum. Duodenojejunostomy was performed. Eight weeks later she presented with painless jaundice. Duodenopancreatectomy revealed a duodenal adenocarcinoma, surrounded by an incomplete AP. Thus, co-existent malignancy with AP can be present without obstructive jaundice and without being visible through preoperative diagnostics. | Enrico Bronnimann Silke Potthast Tatjana Vlajnic Daniel Oertli Oleg Heizmann | 2010 | World Journal of Gastroenterology2010，16，25： | 3 |
| 4 | Calcium regulation of Ndr protein kinase mediated by S100 calcium-binding proteins 显示文摘 | Millward T A Heizmann C W Schefer B W | 1998 | EMBO J1998，17，： | 2 |
| 5 | Expression pattern of S100calcium-binding proteins in human tumors显示文摘 | Ilg EC Schfer BW Heizmann CW | 1996 | Int J Cancer1996，68，3： | 1 |
| 6 | Mitochondrial heteroplasmy among maternally related individuals 显示文摘 | Lutz S Weisser HJ Heizmann J | 1999 | Int J Legal Med1999，113，： | 1 |
| 7 | Distinct cytokine pattern in aqueous humor during immune reactions following penetrating keratoplasty 显示文摘 | Maier P Heizmann U Bohringer D | 2010 | Mol Vis2010，16，： | 1 |
| 8 | An inhibitor of the Tat/TAR RNA interaction that effectively suppresses HIV-1 replication显示文摘 | Hamy F Felder ER Heizmann G | 1997 | Proc Natl Acad Sci USA1997，94，： | 1 |
| 9 | S100B protein in the nervous system and cardiovascular apparatus in normal and pathological condition显示文摘 | Donato R Heizmann CW | 2010 | Cardiovasc Psychiatry Neurol2010，，1： | 1 |
| 10 | Genetic and epidemiological risk factors in the development of bronchopulmonary dysplasia显示文摘 | Mailaparambil B Krueger M Heizmann U | 2010 | Dis Markers2010，29，1： | 1 |
| 11 | Techniques for the segmentation of stria-tion patterns 显示文摘 | HEIZMANN M | 2006 | IEEE Transactions on Image Process-ing2006，15，3： | 1 |
| 12 | S - 100 proteins:structure, functions and pathology 显示文摘 | Heizmann C W Fritz G Schafer B W | 2002 | Front Biosci2002，7，： | 1 |
| 13 | Clinical significance of S100A4 and E - cadherine - relatedadhesion modecules in nonsmall cell lung cancer 显示文摘 | Endo Y Yonemura Y Heizmann CW | 2000 | Int J Oncol2000，16，6： | 1 |
| 14 | Ca(2 + ) signaling in mouse cardiomyocytes with ablated S100A1 protein显示文摘 | Gusev K Ackermann GE Heizmann CW | | Gen Physiol Biophys 20690，28，4： | 1 |
| 15 | Expression pattern of S100 calcium-binding proteins in human tumors显示文摘 | Ilg EC Schafer B W Heizmann C W | 1996 | Int J Cancer1996，68，3： | 1 |
| 16 | The muhifunctional S100 protein family 显示文摘 | Heizmann C W | 2002 | Methods Mol Biol2002，172，： | 1 |
| 17 | An update of the S100 nomenclature显示文摘 | Marenholz I Lovering RC Heizmann CW | 2006 | Biochim Biophys Acta2006，1763，11： | 1 |
| 18 | An update of the S100 nomenclature显示文摘 | Ingo Marenholz Ruth C. Lovering Claus W. Heizmann | 2006 | BBA - Molecular Cell Research2006，，11： | 1 |
| 19 | An update of the S100 nomenclature显示文摘 | Marenholz I Lovering RC Heizmann CW | 2006 | Bioehim Biophys Acta2006，1763，11： | 1 |
| 20 | S100 proteins in mouse andman:from evolution to function and pathology(including an update ofthe nomenclature)显示文摘 | Marenholz I Heizmann CW Fritz G | 2004 | Biochem Biophys Res Commun2004，322，4： | 1 |
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