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| 1 | 策略将在肝移植以后减少丙肝病毒复发显示文摘 Hepatitis C virus (HCV) is a major health problem that leads to chronic hepatitis, cirrhosis and hepatocellular carcinoma, being the most frequent indication for liver transplantation in several countries. Unfortunately, HCV re-infects the liver graft almost invariably following reperfusion, with an accelerated history of recurrence, leading to 10%-30% of patients progressing to cirrhosis within 5 years of transplantation. In this sense, some groups have even advocated for not retransplanting this patients, as lower patient and graftoutcomes have been reported. However, the management of HCV recurrence is being optimized and several strategies to reduce post-transplant recurrence could improve outcomes, decrease the rate of re-transplantation and optimize the use of available grafts. Three moments may be the focus of potential actions in order to decrease the impact of viral recurrence: the pretransplant moment, the transplant environment and the post-transplant management. In the pre-transplant setting, it is not well established if reducing the pre transplant viral load affects the risk for HCV progression after transplant. Obviously, antiviral treatment can render the patient HCV RNA negative post transplant but the long-term benefit has not yet been fully established to justify the cost and clinical risk. In the transplant moment, factors as donor age, cold ischemia time, graft steatosis and ischemia/reperfusion injury may lead to a higher and more aggressive viral recurrence. After the transplant, discussion about immunosuppression and the moment to start the treatment (prophylactic, pre-emptive or once-confirmed) together with new antiviral drugs are of interest. This review aims to help clinicians have a global overview of posttransplant HCV recurrence and strategies to reduce its impact on our patients. | Ruben Ciria María Pleguezuelo Shirin Elizabeth Khorsandi Diego Davila Abid Suddle Hector Vilca-Melendez Sebastian Rufian Manuel de la Mata Javier Briceo Pedro López Cillero Nigel Heaton | 2013 | World Journal of Hepatology2013，5，5： | 2 |
| 2 | Lattice Dynamics, Ther- modynamics and Elastic Properties of Monoclinic Li2 CO3 from Den- sity Functional Theory 显示文摘 | Shang S L Hector L G Shi S Q | 2012 | Acta Mater2012，60，： | 1 |
| 3 | Community structure of denitrifiers bacteria,and Archaea along redox gradients in pacific northwest marine sediments by terminal restriction fragment length polymorphism analysis of amplified nitrite reductase(nirS) and 16S rRNA genes显示文摘 | Gesche Braker Hector L Ayala-Del-Rio Allan H D | 2001 | Appl Environ Microbiol2001，67，4： | 1 |
| 4 | METALLIC URETERAL STENTS FOR THE MANAGEMENT OF BENIGN UPPER URINARY TRACT OBSTRUCTION显示文摘 | Hector L Lopez-Huertas Anthony J Polcari Alex Acosta-Miranda Thomas M t Turk | 2009 | The Journal of Urology2009，，4： | 1 |
| 5 | Effects of Specific Versus Cross-training on Running Performance 显示文摘 | FOSTER C HECTOR L L WELSH R | 1995 | Eur J Appl Physiol Occup Physiol1995，，70： | 1 |
| 6 | Selective inhibition of the oxidation of ferrous iron or sulfur in Thiobacillusferrooxidans显示文摘 | LESIA H HECTOR M L ISAMU S | 2000 | Applied and Environmental Microbiology2000，66，3： | 1 |
| 7 | Thermoelastic stresses in a bonded layer due to repetitively pulsed laser radiation显示文摘 | Kim W S Hector L G Hetnarski R B | 1997 | Acta Mechanica1997，125，： | 1 |
| 8 | “Radicle” biochemistry:the biology of root-specific metabolism显示文摘 | Hector E F Jorge M V Victor M L V | 1999 | Trends in Plant Science1999，4，6： | 1 |
| 9 | A predictive mechanism for dynamic strain ageing in aluminium-magnesium alloys显示文摘 | CURTIN W A OLMSTED D L HECTOR L G | 2006 | Nature Materials2006，，5： | 1 |
| 10 | The future of Ecotoufism 显示文摘 | Ceballos L Hector | 1987 | Mexico Journal1987，，1： | 1 |
| 11 | Thermodynamic and Me- chanical Properties of Lanthanum-Magnesium Phases from Density Functional Theory 显示文摘 | Wrobel J Hector L G Wolf W | 2012 | J Alloys Compd2012，512，： | 1 |
| 12 | Magnetic shielding of levitation melting devices显示文摘 | Sergeant P Hectors D Dupre L | 2010 | IEEE Transactions on Magnetics2010，46，2： | 1 |
| 13 | Percutaneous vertebroplasty for spinal metastases: complications 显示文摘 | Hector Manuel BC Jean-Noel V Daouda L | 2006 | Radiology2006，238，3： | 1 |
| 14 | Anisotropy and Temperature Dependence of Structural, Thermodynamic, and Elastic Prop- erties of Crystalline CeUulose I-Beta: a First-Principles Investigation 显示文摘 | Dri F L Shang S L Hector L G | 2014 | Modelling Simul Mater Sci Eng2014，22，08： | 1 |
| 15 | Cruciform-shaped specimens for elevated temperature biaxial testing of lightweight materials显示文摘 | Abu-Farha F Hector L G Khraisheh M | 2009 | JOM2009，61，8： | 1 |
| 16 | Cyclodextrin-grafted polysaccharides as supramolecular carrier systems for naproxen显示文摘 | RAMIREZ Hector L VALDIVIA Aymara CAO Roberto | 2006 | Bioorganic & Medicinal Chem- istry Letters2006，16，6： | 1 |
| 17 | Hyperbolic heat conduction due to axisymmetric continuous or pulsed surface sources显示文摘 | Kim W S Hector L G Ozisik M N | 1990 | Journal of Applied Physics1990，68，： | 1 |
| 18 | Mierostruetural effects of AZ31 magnesium alloy on its tensile deformation and failure behaviors显示文摘 | Marya M Hector L G Verma R | 2006 | Material Science and Engineering A2006，418，1： | 1 |
| 19 | Tetracycline resistance in Chileanclinical isolates of Helicobacter pylori 显示文摘 | Hector T Remigio L | 2010 | AntimicrobChemother*2010，65，： | 1 |
| 20 | Sample preparation focusing on plant proteomics: extraction, e- valuation and identification of proteins from sunflower seeds显示文摘 | Herbert de S B Daiane L Q de S Hector H F K | 2013 | Anal Methods2013，5，1： | 1 |
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