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| 1 | Current aging research in China显示文摘微型评论在中国在国家老化研究策略上源自一个最近的会议在中国讨论老化研究的部件和挑战。加亮,资助状况和很多个研究队的主要努力研究的最近的专业的突出的例子是成就。最后,作者们在中国讨论老化研究的潜在的目标和策略。 | Ruijuan Sun Heqi Cao Xudong Zhu Jun-Ping Liu Erdan Dong | 2015 | Protein & Cell2015，6，5： | 12 |
| 2 | A LOCKING-FREE SCHEME OF NONCONFORMING RECTANGULAR FINITE ELEMENT FOR THE PLANAR ELASTICITY显示文摘In this paper, the authors present a locking-free scheme of the lowest order nonconforming rectangle finite element method for the planar elasticity with the pure displacement boundary condition. Optimal order error estimate, uniformly for the Lamé constant λ∈(0,∞) is obtained. | Lie-hengWang HeQi | 2004 | Journal of Computational Mathematics2004，22，5： | 9 |
| 3 | ON LOCKING-FREE FINITE ELEMENT SCHEMES FOR THREE-DIMENSIONAL ELASTICITY显示文摘In the present paper, the authors discuss the locking phenomenon oI the lmlte element method for three-dimensional elasticity as the Lamé constant λ→∞. Three kinds of finite elements are proposed and analyzed to approximate the three-dimensional elasticity with pure displacement boundary condition. Optimal order error estimates which are uniform with respect to λ ∈(0,∞) are obtained for three schemes. Furthermore, numerical results are presented to show that, our schemes are locking-free and and the trilinear conforming finite element scheme is locking. | HeQi Lie-hengWang Wei-yingZheng | 2005 | Journal of Computational Mathematics2005，23，1： | 9 |
| 4 | Basic and translational aging research in China: present and future显示文摘The percentage of elderly people in the world is increasing at an unprecedented pace;so it is in China, which has the world s largest population and a high ratio of the seniors (aged 60 and above) to working-age adults. The growing elderly population is presenting a major social challenge. Accordingly, it is not only imperative as a national strategic demand but also promises great scientific values to understand the biological process of aging, explore the mystery of healthy aging, delay the aging process, and treat the age-related diseases. This Perspective summarizes past and present advances of the basic and translational aging research in China and offers perspectives on future endeavors in this area. | Xiaojuan He Moshi Song Jing Qu Yansu Guo Heqi Cao Ruijuan Sun Guang-Hui Liu Yong Shen Major Program Expert Group | 2019 | Protein & Cell2019，10，7： | 8 |
| 5 | 结直肠癌TK、PCNA表达的研究显示文摘目的 通过对结直肠癌及腺瘤中TK和PCNA的表达 ,探讨其对结直肠癌的治疗、预后所起作用。方法 采用免疫组织化学SABC法 ,检测 54例结直肠癌及 2 0例结直肠腺瘤中TK及PCNA的表达。结果 本研究结果表明结直肠癌中TK及PCNA的阳性表达率均比结直肠腺瘤高(P <0 0 5) ,结直肠癌中TK阳性表达率 ( 64 8% )虽略比PCNA ( 51 9% )高 ,但差异无显性 (P >0 0 5)。结论 TK不仅同PCNA一样 ,可作细胞增殖的指标 ,还因其参与DNA合成及细胞间“旁观者效应”等原因 ,从而给临床提供治疗及预后方面的有价值的参考。 | 吴建平 毛军 阎玉虎 刘俐敏 吴传京 HEQi min Sven Skon WANGNai ning Bernhard Tribukait | 2000 | 肿瘤防治研究2000，27，5： | 5 |
| 6 | THE PROGRESS ON SPACE ASTRONOMY IN CHINA DURING 2000-2002显示文摘In this paper main achievements in the area of space astronomy are summarized.During the flight of cosmic Gamma-Ray Burst Spectrometer(GRBS) onboard spacecraft Shenzhou-2(launched on 2001-01-10), much observational results of cosmic γ-ray burst and solar X, γ-ray burst are obtained. The preliminary analysis on space data has lead to some interesting results. Besides it, some other long-term space astronomy programs are briefly described here. | ZHANG Heqi | 2002 | 空间科学学报2002，22，z1： | 4 |
| 7 | Endoplasmic reticulum targeted AIE bioprobe as a highly efficient inducer of immunogenic cell death显示文摘Focused oxidative stress of the specific organelles(e.g.,endoplasmic reticulum(ER)and mitochondrion)of cancer cells can boost the immunogenic cell death(ICD)effect for cancer immunotherapy.Herein,an ER-targeted bioprobe with aggregationinduced emission(AIE)characteristics(TPE-PR-FFKDEL)was rationally designed and synthesized by integrating a new AIE photosensitizer with ER targeting peptide,which has been demonstrated to be able to efficiently induce ER oxidative stress to evoke ICD.Compared with the photosensitizer hypericin that is well-known as an ER-targeted ICD inducer,TPE-PR-FFKDEL can lead to more robust emission of immunostimulatory damage-associated molecular patterns such as surface-exposed calreticulin,ATP secretion,and high-mobility group protein B1(HMGB1)and heat shock protein 70(HSP 70)expression.Furthermore,a range of immune responses are activated to protect mice from the attack of cancer cells in vivo. | Jun Li Heqi Gao Ruihua Liu Chao Chen Sheng Zeng Qian Liu Dan Ding | 2020 | Science China Chemistry2020，63，10： | 2 |
| 8 | Progress of basic research in Parkinson’s disease in China: data mini-review from the National Natural Science Foundation显示文摘This review is to analyze the role of National Natural Science Foundation of China(NSFC)on the development of basic research of Parkinson’s disease from 1990 to 2012.Data on the total number of projects and funding of NSFC allocated to Parkinson’s disease,as well as hotspots in western countries,papers published,awards,personnel training,subject construction were collected,and the role of NSFC on other sources of funding was evaluated.Over the past 23 years,a full range of continuous funding from NSFC has led to fruitful results and a strong impetus to the progress of basic research of Parkinson’s disease. | Heqi Cao Gang Chen Erdan Dong | 2013 | Translational Neurodegeneration2013，2，1： | 2 |
| 9 | Function of GATA transcription factors in hydroxyurea-induced HEL cells显示文摘HEL cells, a human erythroleukemia cell line, mainly express the fetal (r)globin gene and trace amount of the embryonic (E)globin gene, but not adult (B) globin gene. Here we show that hydroxyurea (HU) can induce HEL cells to express adult (B) globin gene and lead these cells to terminal differentiation. Results showed in Gel mobility shift assays that GATA factors could specifically bind to the regulatory elements of human B- globin gene, including the proximal regulatory element (the B- promoter) and the distal regulatory elements (the DNase I hypersensitive sites in the LCR, HS2-HS4 core sequences). However, the DNA binding patterns of GATA factors were quite different between HU-induced and uninduced HEL cells. Western-blot analysis of nuclear extracts from both the uninduced and HU- induced HEL cells revealed that the level of GATA-2 transcription factor decreased, whereas the level of GATA-1 transcription factor increased following the time of hydroxyurea induction. Furthermore, using RT-PCR analysis the expression of human B-globin gene in HU-induced HEL cells could be blocked again when HEL cells were incubated in the presence of antisense oligonucleotides for hGATA-1, suggesting that the upregulation of hGATA-1 transcription factor might be critical for the expression of human β- globin gene in HU-induced HEL cells. | ZhanSB HeQY | 2001 | Cell Research2001，11，4： | 2 |
| 10 | Ultrastable and colorful afterglow from organic luminophores in amorphous nanocomposites:Advanced anti-counterfeiting and in vivo imaging application显示文摘Special attention has been paid to the organic afterglow materials(OAM)for their fascinating properties.However,poor stability at air and complicated structure design hinder the development of OAM.Herein,sol-gel,a facile and simple technique,is employed to synthesize a series of organic/inorganic hybrid nanocomposites(N1/SiO2,N2/SiO2,and N3/SiO2)by covalently linking three common aryl imides with crosslinked silica skeleton.These nanomaterials show excitation wavelength-dependent and colorful(yellow,red and green)afterglow of organic imides with long lifetime up to 1.1 s at air.Interestingly,the ultralong phosphorescence is ultrastable under various conditions:water,high temperature,UV irradiation and in vivo,due to the protection of inorganic silica.In particularly,heating to 500℃does not quench the afterglow of organic luminophore in nanocomposites,but forms new ultralong phosphorescence originated from space-conjugation of silica and carbonyl.The afterglow nanomaterials display huge advantages in the applications of advanced anti-counterfeiting and bioimaging. | Qiuqin Huang Heqi Gao Shuming Yang Dan Ding Zhenghuan Lin Qidan Ling | 2020 | Nano Research2020，13，4： | 2 |
| 11 | An effec- tive hybrid firefly algorithm with harmony search for global numerical optimization 显示文摘 | Guo Lihong Wang Gaige Wang Heqi | 2013 | The Scientific World Journal2013，，： | 1 |
| 12 | Thermal decomposition of some perfluoro-and polyfluorodiacyl peroxides显示文摘 | Zhao chengxue Zhou renmo Pan Heqi | 1982 | J Org Chem1982，47，11： | 1 |
| 13 | Research on kansei image-driven method of product styling design显示文摘 | SU Jianning JIANG Pingyu LI Heqi | 2009 | International Journal of Product Development2009，7，12： | 1 |
| 14 | Research on kansei image-driven method of product styling design显示文摘 | Su Jianning Jiang Pingyu Li Heqi | | 0，，1： | 1 |
| 15 | Research on kansei image-driven method of product styling design显示文摘 | Su Jianning Jiang Pingyu Li Heqi | | 0，，1： | 1 |
| 16 | Recent developments in the use of chemotherapy in brain tumours显示文摘 | Van den Bent MJ Heqi ME Stupp R | 2006 | Eur J Cancer2006，42，： | 1 |
| 17 | Research on kansei image-driven method of product styling design 显示文摘 | SU Jianning JIANG Pingyu LI Heqi | 2009 | International Journal of Product Development2009，7，12： | 1 |
| 18 | SOME NEW STATISTICAL PROPERTIES OF SOLAR HARD X-RAY, GAMMA RAY BURSTS AND THIER ASTROPHYSICAL IMPLICATION FOR CHARGED PARTICLE ACCELERATION IN SOLAR FLARE显示文摘In this paper the SMM / GRS data obtained during the last solar maximum are studied. Some new statistical properties of hard X-ray and γ-ray bursts pointes out here will be significant in establishing the model of particle acceleration in solar flare. Much theoretical analyses for these results remain to be done in future. | Zhang Heqi, Yin ChunlinPurple Mountain ObservatoryXu AoaoAstronomy Department of Nanjing University | 1990 | 天文研究与技术1990，，4： | 1 |
| 19 | Antiangiogenic effects of oxymatrine on pancreatic cancer by inhibitionof the NF-κB-mediated VEGF signaling pathway显示文摘 | Hui Chen Jianhong Zhang Jiang Luo Fuji Lai Zhaohong Wang Hongfei Tong Dian Lu Heqi Bu Riyuan Zhang Shengzhang Lin | 2013 | Oncology Reports2013，，2： | 1 |
| 20 | Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTCNCIC trial显示文摘 | Stupp R Heqi ME Mason WP | 2009 | Lancet Oncol2009，10，5： | 1 |
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