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| 1 | MEF13 Requires MORF3 and MORF8 for RNA Editing at Eight Targets in Mitochondrial mRNAs in Arabidopsis thaliana显示文摘在植物线粒体和质体编辑地点的 RNA 被 pentatricopeptide 探讨有 E 或 E 和 DYW 领域的重复(PPR ) 蛋白质,它认出编辑核苷酸在上游的一个特定的核苷酸主题。另外,一些地点为编辑的有效 RNA 要求 MORF 蛋白质。这里,我们分配新奇 E 包含域的 PPR 蛋白质, MEF13 为在 Arabidopsis thaliana 在八个地点编辑被要求。在改变编辑水平在的生态型 C24 的 SNP 仅仅,八个目标地点之一被印射的 genomic 定位。为 MEF13 的基因的他们变异的等位基因在一张变异的植物人口的一幅快照屏幕被识别。根本 MEF13 的八个目标地点,编辑层次在 morf3 和 morf8 异种被减少,但是在仅仅在 morf1 异种的一个地点,建议特定的 MEF13-MORF 相互作用被要求。酵母二混血儿的分析与有 MORF3 蛋白质的 MORF1 和弱接触检测 MEF13 的稳固的连接。酵母三混血儿(Y3H ) 分析证明 MORF8 的存在提高在 MEF13 和 MORF3 之间的连接,建议 MORF3-MORF8 heteromer 可以稳定地或短暂地形成与 MEF13 建立相互作用。 | Franziska Glass Barbara Hartel Anja Zehrmann Daniil Verbitskiy Mizuki Takenaka | 2015 | Molecular Plant2015，8，10： | 8 |
| 2 | Pain sensation in pancreatic diseases is not uniform: The different facets of pancreatic pain显示文摘AIM: To systematically characterize specific pain patterns in the most frequent pancreatic diseases.METHODS: Pain in patients with chronic pancreatitis(n = 314), pancreatic cancer(n = 469), and other pancreatic tumors(n = 249) including mucinous(n = 20) and serous cystadenoma(n = 31), invasive(n = 37) and non-invasive intraductal papillary mucinous neoplasia(IPMN; n = 48), low stage(n = 18) and high stage neuroendocrine neoplasia(n = 44), and ampullary cancer(n = 51) was registered and correlated with clinicopathological data. Survival times were estimated by the Kaplan-Meier method. Patients alive at the follow-up time were censored. Survival curves were compared statistically using the log-rank test.RESULTS: Forty-nine point one percent of pancreatic cancer patients revealed no pain, whereas in chronic pancreatitis only 18.3% were pain free. In contrary, moderate/severe pain was registered in 15.1% in pancreatic cancer patients that was increased in chronic pancreatitis with up to 34.2%. Serous cystadenoma was asymptomatic in most cases(58.1%), whereas 78.9% of all mucinous cystadenoma patients suffered pain. In neuroendocrine neoplasia pain was not a key clinical symptom since 64% of low stage neuroendocrine neoplasia and 59% of high stage neuroendocrine neoplasia patients were pain free. Cancer localization in the pancreatic body and patients with malignant pancreatic neoplasms were associated with more severe pain. Tumor grading and stage did not show any impact on pain. Only in pancreatic cancer, pain was directly associated with impaired survival.CONCLUSION: Pancreatic pain depicts different patterns of abdominal pain sensation according to the respective pancreatic disorder and does not allow a unification of the term pancreatic pain. | Jan G D'Haese Mark Hartel Ihsan Ekin Demir Ulf Hinz Frank Bergmann Markus W Büchler Helmut Friess Güralp O Ceyhan | 2014 | World Journal of Gastroenterology2014，20，27： | 8 |
| 3 | TuLP: A Family of Lightweight Message Authentication Codes for Body Sensor Networks显示文摘A wireless sensor network(WSN) commonly requires lower level security for public information gathering, whilst a body sensor network(BSN) must be secured with strong authenticity to protect personal health information. In this paper, some practical problems with the message authentication codes(MACs), which were proposed in the popular security architectures for WSNs, are reconsidered. The analysis shows that the recommended MACs for WSNs, e.g., CBCMAC(TinySec), OCB-MAC(MiniSec), and XCBC-MAC(SenSec), might not be exactly suitable for BSNs. Particularly an existential forgery attack is elaborated on XCBC-MAC. Considering the hardware limitations of BSNs, we propose a new family of tunable lightweight MAC based on the PRESENT block cipher. The first scheme, which is named TuLP, is a new lightweight MAC with 64-bit output range. The second scheme, which is named TuLP-128, is a 128-bit variant which provides a higher resistance against internal collisions. Compared with the existing schemes, our lightweight MACs are both time and resource efcient on hardware-constrained devices. | 龚征 Pieter Hartel Svetla Nikova 唐韶华 朱博 | 2014 | Journal of Computer Science & Technology2014，29，1： | 2 |
| 4 | Engineering analysis of hazards to life safety in fires: the fire effluent toxicity component 显示文摘 | Hartell G E | 2001 | Safety Science2001，38，2： | 1 |
| 5 | Programmable illu- mination and high-speed, multi-wavelength, confocal mi- croscopy using a digital micromirror显示文摘 | Martial Franck P Hartell Nicholas A | 2012 | PL o S One2012，7，43： | 1 |
| 6 | Engineering analysis of hazards to life safety in fires : the fire effluent toxicity component 显示文摘 | Hartell G E | 2001 | Safety Science2001，38，2： | 1 |
| 7 | Staging laparoscopy and its indications in pancreatic cancer patients显示文摘 | Hennig R Tempia-Caliera AA Hartel M | 2002 | Dig Surg2002，19，6： | 1 |
| 8 | Misidentification of soil bacteria by fatty acid methyl ester (FAME) and biolog analyses显示文摘 | Oka N Hartel P G Finlay-Moore O | 2000 | Biology and Fertility of Soils2000，32，3： | 1 |
| 9 | National cancer institute's thesaurus and ontology显示文摘 | Golbeck J Fragoso G Hartel F | 2003 | Journal of Web Semantics2003，，： | 1 |
| 10 | Misidentification of soil bacteria by fatty acid methyl ester(FAME)and BIOLOG analyses显示文摘 | OKA N HARTEL P G FINLAY M O | 2000 | Biology&Fertility of Soils2000，32，3： | 1 |
| 11 | Renal complications associated with human parvovims B19 infection in early childhood 显示文摘 | Hartel C Herz A Vieth S | 2007 | Kiin Pediatr2007，219，2： | 1 |
| 12 | Response after one dose of a monovalent influenza A (H1N1) 2009 vaccine-preliminary report 显示文摘 | Greenberg ME Lai MH Hartel GF | 2009 | N Engl J Med2009，361，25： | 1 |
| 13 | Abstract machines for programming language implementation 显示文摘 | Diehl S Hartel P Sestoft P | 2000 | Future Generation Computer Systems2000，16，： | 1 |
| 14 | Evidence for de novo synthesis of cytokines and chemokines in platelet concentrates显示文摘 | HARTWIG D HARTEL C HENNIG H | 2002 | Vox Sang2002，82，： | 1 |
| 15 | Expression and localization of human multidrug resistance protein (ABCC) family members in pancreatic carcinoma显示文摘 | Konig J Hartel M Nies AT | 2005 | Int J Cancer2005，115，3： | 1 |
| 16 | A chimeric humanized single - chain antibody against the type 1 insulin - like growth factor (IGF) receptor renders breast cancer cells refractory to the mitogenie effects of IGF - 1 显示文摘 | SACHDEV D LI S L HARTELL J S | 2003 | Cancer Res2003，63，： | 1 |
| 17 | Engineering analysis of hazards to life safety in fires : the fire effluent toxicity component显示文摘 | Hartell GE | 2001 | Safety Science2001，38，2： | 1 |
| 18 | Engineering analysis of hazards to life safety in fires:the fire effluent toxicity component显示文摘 | Hartell G E | 2001 | Safety Science2001，38，2： | 1 |
| 19 | Primary pulmory and mediastimal synovial sarcoma: a clinieopathologie study of 60cases and comprison with five prior series显示文摘 | Hartel PH Fanburg-Smith JC Frazier AA | 2007 | Mod Pathol2007，20，7： | 1 |
| 20 | Unstable bicondylar tibial plateau fractures:a clinical investigation显示文摘 | Eggli S Hartel MJ Kohl S | | 0，，10： | 1 |
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