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| 1 | Anti-cancer effects of hydro-alcoholic extract of pericarp of pistachio fruits显示文摘Objective:To investigate the cytotoxicity and anti-cancer effects of hydro-alcoholic extract of pistachio pericarp on hepatocellular carcinoma cells(HepG2)and mouse fibroblast L929 cells as normal and control group cell.Methods:MTT assay was performed to investigate the cytotoxicity effects of the extract at 0-4 000μg/mL on the cells after 24 and48 h.The expressions of some genes involved in apoptosis including Bax,Bcl-2 and P53were investigated by real time PCR.Results:Our results showed that after 24 and 48 hours of treatment of cells with this extract,the viability of HepG2 and L929 cells was reduced.Therefore,this extract had the cytotoxicity effect on both cells.The IC_(50) concentration of extract for HepG2 cells after 24 and 48 hours of treatment was 1 500 and 1 000μg/mL and for L929 cells was 2 000 and 1 500μg/mL,respectively.The expressions of Bax and P53 genes were up-regulated after treatment in the HepG2 and L929 cells and the expression of Bcl-2gene was down-regulated after treatment of extract in HepG2 cell.Conclusions:According to the results of MTT assay and real time PCR,this extract can be considered as a potential candidate for use in the production of anti-cancer drugs for the treatment of patients with liver cancer in future. | Hamidreza Harandi Ahmad Majd Soudeh Khanamani Falahati-pour Mehdi Mahmoodi | 2018 | Asian Pacific Journal of Tropical Biomedicine2018，8，12： | 2 |
| 2 | Molecular and morphological characterization of the tapeworm Taenia hydatigena (Pallas, 1766) in sheep from Iran显示文摘 | S. Rostami R. Salavati R.N. Beech Z. Babaei M. Sharbatkhori M.R. Baneshi E. Hajialilo H. Shad M.F. Harandi | 2013 | Journal of Helminthology2013，，2： | 2 |
| 3 | A protective role of locally administered immunostimulatory CpG oligodeoxynucleotide in a mouse model of genital herpes infection显示文摘 | Harandi A M Eriksson K Holmgren J | 2003 | J Virol2003，77，2： | 1 |
| 4 | Evaluation of fibroblast at- tachment in root conditioning with Er, Cr:YSGG laser versus ED- TA:A SEM study 显示文摘 | Fekrazad R Lotfi G Harandi M | 2015 | Microsc Res Tech2015，78，4： | 1 |
| 5 | Memantine for axonal loss of optic neuritis显示文摘 | Esfahani MR Harandi ZA Movasat M | 2012 | Graefes Arch Clin Exp Ophthalmol2012，250，6： | 1 |
| 6 | Polyethyleneimine is a potent mucosal adjuvant for viral glycoprotein antigens 显示文摘 | WEGMANN F GARTLAN K H HARANDI A M | 2012 | Nat Biotechnol2012，30，9： | 1 |
| 7 | Glycoprotein G of herpes simplex virus 2 as a novel vaccine antigen for immunity to genital and neurological disease显示文摘 | GORANDER S HARANDI A M LINDQVIST M | 2012 | J Virol2012，86，14： | 1 |
| 8 | Interleukin-12(IL-12) and IL-18 are important in innate defense against genital herpes sim- plex virus type 2 interferon-mediated Cunn protective immunity显示文摘 | Harandi AM Svennerholmb B Holmgren I | 2007 | Jvi- rol2007，75，14： | 1 |
| 9 | CpG oligodeoxynucleotides and mobili-zation of innate mucosal immunity:tasks and tactics显示文摘 | Harandi AM Holmgren J | | 0，，2： | 1 |
| 10 | Association of serum 25 (OH) vitamin D3 concentration with severity of multiple sclerosis 显示文摘 | Harandi AA Shahbeigi S Pakdaman H | 2012 | Iran J Neurol2012，11，2： | 1 |
| 11 | Subcision-suction method:a new successful combination therapy in treatment of airophic acne scars and other depressed scars显示文摘 | Aalami Harandi S Balighi K Lajevardi V | 2011 | J Eur Acad Dermatol Venereol2011，25，1： | 1 |
| 12 | Differential immunocytochemical staining for glial fibrillary acidic (GFA) protein, S-100 protein and glutamine synthetase in the rat subcommissural organ, nonspecialized ventricular ependyma and adjacent neuropil显示文摘 | Didier M Harandi M Aguera M | 1986 | Cell Tissue Res1986，245，2： | 1 |
| 13 | A protective role of locally administered immunostimulatory CpG oligodeoxynucleotide in a mouse model of genital herpes infection显示文摘 | Eriksson K Holmgren J | 2003 | J Virol2003，77，2： | 1 |
| 14 | A fixed point theo- rem for contraction type maps in partially ordered metric spaces and application to 显示文摘 | AMINI - HARANDI A EMANI H | 2010 | Nonlinear Analysis ordinary differential equations2010，35，72： | 1 |
| 15 | Effect of forging process on microslructure, mechanical and corrosion properties of biodegradable MgCa alloy显示文摘 | Harandi S E Idris M H Jafari H | 2011 | Materials and Design2011，32，25： | 1 |
| 16 | Molecular and cellular mechanism of lung injuries due to exposure to sulfur mustard:a review显示文摘 | Ghanei M Harandi AA | | Inhal Toxicol0，20，7： | 1 |
| 17 | The potential of immunostimulatory CpG DNA for inducing immunity against genital herpes: opportunities and challenges显示文摘 | Harandi A M | 2004 | J Clin Virol2004，30，3： | 1 |
| 18 | Molecular and cellular mechanism of lung injuries due to exposure to sulfur mastard: a review显示文摘 | GHANEI M HARANDI A A | 2011 | Inhal Toxicol2011，23，7： | 1 |
| 19 | Finite element analysis of deformation and fracture of an exploded gas cylinder显示文摘 | Majid Mirzaei Amir Harandi Reza Karimi | 2009 | Engineering Failure Analysis2009，，16： | 1 |
| 20 | A protective role of locally administered immunostimulatory CpG oligodeoxynucleotide in a mouse model of genital herpes infection显示文摘 | Harandi AM Eriksson K Holmgren J | 2003 | J Virol2003，77，： | 1 |
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