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| 1 | Novel hydrophobic associated polymer based nano-silica composite with core–shell structure for intelligent drilling fluid under ultra-high temperature and ultra-high pressure显示文摘Micro-nano-based drilling fluid has attracted a strong interest due to its attractive properties, and micro-nano composite materials have great potential for developing intelligent drilling fluid. In this study a novel hydrophobic associated polymer based nano-silica composite with core–shell structure was prepared and characterized by PSD, SEM, TEM and ESEM. The results showed that the composite, as a micro-nano drilling fluid additive, possessed excellent properties such as thermal stability, rheology, fluid loss and lubricity. Especially, it could plug the formation effectively and improve the pressure bearing capability of formation significantly. | Hui Mao Zhengsong Qiu Zhonghou Shen Weian Huang Hanyi Zhong Wenhao Dai | 2015 | Progress in Natural Science:Materials International2015，25，1： | 7 |
| 2 | Design of PANDA ring-core fiber with 10 polarization-maintaining modes显示文摘We present a polarization-maintaining PANDA ring-core fiber(PM-PRCF) characterized by the combination of a ring-core structure with two stress-applying rods. This special fiber design separates the adjacent modes and avoids the cutoff of the higher-order modes, which is a common problem in elliptical core polarization-maintaining few-mode fibers. Using a high-contrast index ring and stress-induced birefringence, the PM-PRCF features support for 10 vector modes, with effective refractive index separations from their adjacent modes >10^(-4).Broadband performance is investigated subsequently over a wide wavelength range from 1500 to 1630 nm.The proposed fiber is targeted at applications in space-division multiplexing while eliminating the complex multiple-input multiple-output signal processing. | Haozhe Yan Shangyuan Li Zhengyang Xie Xiaoping Zheng Hanyi Zhang Bingkun Zhou | 2017 | Photonics Research2017，5，1： | 7 |
| 3 | Ultra-sensitive Nanoprobe Modified with Tumor Cell Membrane for UCL/MRI/PET Multimodality Precise Imaging of Triple-Negative Breast Cancer显示文摘Triple-negative breast cancer(TNBC)is a subtype of breast cancer in which the estrogen receptor and progesterone receptor are not expressed,and human epidermal growth factor receptor 2 is not amplified or overexpressed either,which make the clinical diagnosis and treatment very challenging.Molecular imaging can provide an effective way to diagnose TNBC.Upconversion nanoparticles(UCNPs),are a promising new generation of molecular imaging probes.However,UCNPs still need to be improved for tumor-targeting ability and biocompatibility.This study describes a novel probe based on cancer cell membrane-coated upconversion nanoparticles(CCm-UCNPs),owing to the low immunogenicity and homologous-targeting ability of cancer cell membranes,and modified multifunctional UCNPs.This probe exhibits excellent performance in breast cancer molecular classification and TNBC diagnosis through UCL/MRI/PET tri-modality imaging in vivo.By using this probe,MDA-MB-231 was successfully differentiated between MCF-7 tumor models in vivo.Based on the tumor imaging and molecular classification results,the probe is also expected to be modified for drug delivery in the future,contributing to the treatment of TNBC.The combination of nanoparticles with biomimetic cell membranes has the potential for multiple clinical applications. | Hanyi Fang Mengting Li Qingyao Liu Yongkang Gai Lujie Yuan Sheng Wang Xiao Zhang Min Ye Yongxue Zhang Mingyuan Gao Yi Hou Xiaoli Lan | 2020 | Nano-Micro Letters2020，12，5： | 5 |
| 4 | INFLUENCE OF PHASE COMPOSITION ON PITTING CORROSION RESISTANCE OF SPUTTERED COATING OF 1Cr18Ni9Ti STAINLESS STEEL显示文摘A series of single bcc,bcc plus fcc duplex and single fcc microcrystalline coatings of1Cr18Ni9Ti stainless steel were prepared by using sputtering technique.The resistanceagainst pitting corrosion was studied by measurements of pitting corrosion potentials andelectrochemical noise during initiation of corrosion pits.The results show that the sputteredcoatings with single bcc phase or single fcc structure are more resistant to pitting corrosionthan those with bcc plus fcc duplex phase structure. | LIU Dacheng WANG Fuhui CAO Chunan LOU Hanyi Institute of Corrosion and Protection of Metals,Academia Sinica,Shenyang,China Wang Fuhui,Laboratory of Electrochemistry,Institute of Corrosion and Protection of Metals,Academia Sinica,Shenyang 110015,China | 1990 | Acta Metallurgica Sinica(English Letters)1990，3，8： | 3 |
| 5 | Oxidation Behaviour of Sputtered Ni-3Cr-20Al Alloy显示文摘The oxidation behavior of sputtered Ni-3Cr-20Al coating at 900℃ in air was investigated. A dense Al2O3 layer was formed on the sputtered Ni-3Cr-20Al coating after 200 h oxidation. However, owing to the segregation of Ni3Al during oxidation process at high temperature, the spinel NiAl2O4 was also formed in the Al2O3 layer. It was found that the formation of NiAl2O4 had no detrimental effect on the oxidation resistance of the sputtered Ni-3Cr-20Al coating due to the excellent adhesion shown by the Al2O3 and NiAl2O4 complex oxide scale. | Guofeng CHEN and Hanyi LOU (State Key Laboratory for Corrosion and Protection, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110015, China) | 2000 | Journal of Materials Science & Technology2000，16，1： | 3 |
| 6 | The velocity structure of the Yinggehai Basin and its hydrocarbon implication显示文摘Two profiles of refraction and wide_angle reflection were completed in the Yinggehai Basin using ocean bottom hydrophones (OBHs) as receiver. These profiles reveal a low velocity layer (LVL) to the west of No. 1 Fault in the basin, with velocity of 3.0-3.5 km/s. Its upper interface lies at 3.5 km below the sea bottom at the NE end of the profiles, and deepens southwestward to 4 6 km near the axis of the basin. It coincides with the top of a gas_bearing, high_pressure layer defined by well logging. This suggests that the LVL is a layer of less_compacted and gas_charged sediments. The lower interface of the LVL is about 9 km in depth. Sediments above the LVL have velocity varying from 2 0 to 4 1 km/s. The acoustic basement is found only east of No. 1 Fault, with velocity of 5 8-6 2 km/s. A NNW_SSE_running OBH seismic profile across the Xisha Trough was completed on the same cruise. Moho and other deep interfaces are clearly visible in the profile. | Kanyuan Xia Di Zhou Daquan Su E. Flueh Sanyu Ye Hanyi He Weidong Chen Yuhong Xie Guixian Wang Saijun Liu et al. | 1998 | Chinese Science Bulletin1998，43，24： | 3 |
| 7 | Tailoring combinatorial lipid nanoparticles for intracellular delivery of nucleic acids, proteins,and drugs显示文摘Lipid nanoparticle(LNP)-based drug delivery systems have become the most clinically advanced non-viral delivery technology.LNPs can encapsulate and deliver a wide variety of bioactive agents,including the small molecule drugs,proteins and peptides,and nucleic acids.However,as the physicochemical properties of small-and macromolecular cargos can vary drastically,every LNP carrier system needs to be carefully tailored in order to deliver the cargo molecules in a safe and efficient manner.Our group applied the combinatorial library synthesis approach and in vitro and in vivo screening strategy for the development of LNP delivery systems for drug delivery.In this Review,we highlight our recent progress in the design,synthesis,characterization,evaluation,and optimization of combinatorial LNPs with novel structures and properties for the delivery of small-and macromolecular therapeutics both in vitro and in vivo.These delivery systems have enormous potentials for cancer therapy,antimicrobial applications,gene silencing,genome editing,and more.We also discuss the key challenges to the mechanistic study and clinical translation of new LNP-enabled therapeutics. | Yamin Li Zhongfeng Ye Hanyi Yang Qiaobing Xu | 2022 | Acta Pharmaceutica Sinica B2022，12，6： | 3 |
| 8 | Anti-fatigue activity of Brassica rapa L.extract and correlation among biochemical changes in forced swimming mice显示文摘Brassica rapa L.is an edible and medical plant in China used for treating various diseases,especially in the Tibet region.In this study,the chemical constituents of Brassica rapa L.extract(BE)was clarified by UHPLC-MS and anti-fatigue ability of BE was assessed through the behavior test and weight-loaded forced swimming test in mice.Then we determined several biochemical parameters related to fatigue to explore possible reasons.Results indicate that BE could significantly enhance exercise performance in mice,and there was a significant improvement in both grip-strength and the time on rota-rods.Meanwhile,BE showed significant anti-fatigue effects by decreasing the blood lactic acid(BLA),blood urea nitrogen(BUN),and creatine kinase(CK)levels and increasing the lactate dehydrogenase(LDH)and malondialdehyde(MDA)levels.Increases in superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px)were observed and reactive oxygen species(ROS)levels was regulated.Liver and muscle glycogen levels and adenosine triphosphate(ATP)levels were also significantly increased.Pearson correlation analysis indicates that fatigue-related indexes including metabolites and energy-related indexes were significantly correlated with antioxidant levels.In conclusion,BE possesses remarkable anti-fatigue activity,thereby shows great potential for improving exercise performance and alleviating physical fatigue and can be considered as a functional food supplement for further development. | Zilin Li Hongkang Zhu Hanyi Hua Chang Liu Yuliang Cheng Yahui Guo Peng Du He Qian | 2022 | Food Bioscience2022，47，3： | 2 |
| 9 | Sources,dynamics in vivo,and application of astaxanthin and lutein in laying hens:A review显示文摘Astaxanthin(Ax)and lutein are important fat-soluble pigments and essential nutrients for human and animal health.Haematococcus pluvialis microalga and Phaffia rhodozyma yeast are ideal species for commercial Ax production.Marigold flowers are a main source of commercial lutein.Dynamics of dietary Ax and lutein in the gastrointestinal tract are similar to lipids,but their activities are tremendously challenged by many physiological and dietary factors;few data are available about these in poultry.Dietary Ax and lutein have insignificant effects on egg production and egg physical properties,but have pronounced effects on yolk color,nutrition,and functionality.The two pigments can also enhance antioxidative capacity and immune function of laying hens.A few studies have shown that Ax and lutein can improve fertilization and hatchability of laying hens.Considering the pigmentation and health benefits of Ax and lutein from hen feed to human food,the commercial availability,chicken yolk improvement,and immune function of Ax and lutein are the focuses of this review.The potential roles of carotenoids in the cytokine storm and gut microbiota are also briefly presented.The bioavailability,metabolism,and deposition of Ax and lutein in laying hens are suggested for future research. | Hanyi Shi Xuejuan Deng Xiaoyu Ji Ning Liu Huiyi Cai | 2023 | Animal Nutrition2023，，2： | 2 |
| 10 | Dynamic routing and wavelength sssignment for two-stage multi-granularity WDM optical networks显示文摘 | Zheng Xiaoping Qin T Zhang Hanyi | 2004 | Optics Communications2004，229，： | 2 |
| 11 | Diphenyl cyclopropenone-centered polymers for site-specific CO-releasing and chain dissociation显示文摘The synthesis and stimuli-responsiveness of a diphenyl cyclopropenone(DPCP)-centered poly(methyl acrylate)(PMA)are presented.DPCP-centered PMA could release carbon monoxide(CO)upon UV light in a switched on-and-off manner.The CO-releasing process can be reported by the variations in photoluminescence spectra.In addition,DPCP moiety covalently embedded in the crosslinked polyurethane could also release CO under UV light.Of special,DPCP-centered PMA in solution was selectively dissociated at the phenol ester bond under the ultrasound,and a force-induced hydrolyzation reaction was revealed by D20 exchanging^1 H NMR spectra.The kinetic study reveals that small quantity of water could enhance the chain scission rate.This work provides a DPCP-centered polymer for sitespecific CO-releasing and chain dissociation. | Chenchen Shao Hanyi Duan Yuqin Min Xinghong Zhang | 2020 | Chinese Chemical Letters2020，31，1： | 2 |
| 12 | CYCLIC OXIDATION BEHAVIOUR OF MICROCRYSTALLIZED CoCrAl COATING显示文摘An investigation was carried out of the resistance to cyclic oxidation of the as-castnormal-grained Co-30Cr-5Al alloy substrate at 1000℃ in air together with its sputteredcoating of microcrystallized CoCrAl alloy grains sized less than 0.5μm.Acoustie emissi oncounts showed that the initially formed Al2O3 scale on the bare alloy substrate cracked andspalled severely off after only one or two cycles on cooling and then the worse protective layerof Cr2O3 and CoCr2O4 spinel occurred on surface.While such substrate coated withsputtered microcrystallized CoCrAl alloy film was not damaged under oxidation even through100 cycles at 1000℃.In comparison with the normal-grained alloy,the microcrystallized al-loy,coating of similar constitution exhibite excellent resistance to oxide spalling on surface. | WANG Fuhui LOU Hanyi WU Weitao Corrosion Science Laboratory,Institute of Corrosion and Protection of Metals,Academia Sinica,Shenyang,China Research Assistant,Institute of Corrosion and Protection of Metals,Academia Sinica,Shenyang 110015,China | 1992 | Acta Metallurgica Sinica(English Letters)1992，5，9： | 1 |
| 13 | Highly linear radio-over-fiber system incorporating a single-drive dual- parallel Mach-Zehnder modulator 显示文摘 | Li Shangyuan Zheng Xiaoping Zhang Hanyi | 2010 | Photon Technol Lett2010，22，24： | 1 |
| 14 | An Efficient Distributed Control Scheme for Lightpath Establishment in Dynamic WDM Networks显示文摘 | Feifei Feng Xiaoping Zheng Hanyi Zhang Yili Guo | 2004 | Photonic Network Communications2004，，1： | 1 |
| 15 | Hydrological simulation by SWAT model with fixed and varied parameterization approaches under land use change显示文摘 | Du Jinkang Rui Hanyi Zuo Tianhui | 2013 | Water Resour Manage2013，，27： | 1 |
| 16 | A kind of topology aggregation algorithm in hierarchical wavelength-routed optical networks显示文摘 | Zhang Feng Zheng Xiaoping Zhang Hanyi | 2005 | Photonic Network Communications2005，9，2： | 1 |
| 17 | Evaluation of beat noise in OCDMA system with Non-Gaussian approximated method 显示文摘 | PU Tao ZHANG Hanyi GUO Yili -t al | 2006 | Journal of Lightwave Technology2006，24，10： | 1 |
| 18 | A novel approach to all-optical generation of ultra- wideband signals 显示文摘 | XIANG Peng ZHENG Xiaoping ZHANG Hanyi | 2013 | Fiber and Integrated Optics2013，32，3： | 1 |
| 19 | A study on the compo- sition optimization and mechanical properties of A1-Mg-Si cast al- loys显示文摘 | ZHANGXH SUGC HANYY etal | 2010 | Materials Science and Engineering2010，527，16： | 1 |
| 20 | Oxidation kinetics of sputtered Ni-5Cr-5Al nanocrystalline coating at 900°c and 1000°c显示文摘 | Guofeng Chen Hanyi Lou | 1999 | Nanostructured Materials1999，，5： | 1 |
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