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48篇 您的检索式:作者名="Hammann A"
    题名 作者 年代 出处 被引量
1Plasma phospholipid transfer protein (PLTP) modulates adaptive immune functions through alternation of T helper cell polarization显示文摘客观:血浆 phospholipid 转移蛋白质(PLTP ) 是脂蛋白新陈代谢的一个关键决定因素,并且动物和人的研究收敛显示 PLTP 支持 atherogenesis 和它的 thromboembolic 复杂并发症。而且, PLTP 调制发炎和有免疫力的回答,这最近被报导了。尽管从我们的组的更早的研究证明 PLTP 能修改巨噬细胞激活,在 T-cell-mediated 有免疫力的回答的调整的 PLTP 的含意从来没被调查过并且因此在现在的学习被探讨。途径和结果:在现在的学习,我们证明在老鼠的那 PLTP 缺乏在 CD4 + Th0 房间极化上有深刻效果,与向在正常、病理学的条件下面的反煽动性的 Th2 显型的移动。在接触超敏性的一个模型,对有 hapten-2,4-dinitrofluorobenzene (DNFB ) 的皮肤促进感受性的显著地损害的回答在 PLTP 缺乏的老鼠被观察与相比野类型(WT ) 老鼠。有趣地,在老鼠的 PLTP 缺乏没在外部血在全部的白血房间,淋巴细胞, granulocytes,或单核白血球的计数上施加效果。而且, PLTP 缺乏没修改 CD4 + 和 CD8 + T 淋巴细胞子集的数量。然而, PLTP 缺乏,与 Th2 显型的 upregulation 联系了,被重要减少在 pro-Th1 cytokine interleukin 的生产伴随 18 由附件房间。结论:第一次,这个工作向支持 inflammatory Th1 显型在 CD4 + T 房间的极化为 PLTP 报导一个生理的角色。Catherine Desrumau Stephanie Lemaire-Ewing Nicolas Ogier Akadiri Yessoufou Arlette Hammann Anabelle Sequeira-Le Grand Valerie Deckert Jean-Paul Pais de Barros Naig Le Guern Julien Guy Naim A Khan Laurent Lagrost 2016Cellular & Molecular Immunology2016,13,6:3
2Sensitization of cancer cells treated with cytotoxic drugs to fas - mediated eytotoxicity显示文摘Micheau O Solarv E Hammann A 1997J Natl Cancer lnst1997,89,11:1
3Fas ligand-independent,FADD-mediated activation of the Fas death pathway by anticancer drugs显示文摘Micheau O Solary E Hammann A 1999J Bio Chem1999,274,:1
4Sensitization of cancer cells treated with cytotoxic drugs to fas-mediated cytotoxicity显示文摘Micheau O Solary E Hammann A 1997J Natl Cancer Inst1997,89,11:1
5MT Anficancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis 显示文摘Lacour S Hammann A Wotawa A 2001Cancer Res2001,61,4:1
6Chemotherapy enhances TNF-related apoptosis-inducing ligand DISC assembly in HT29 human colon cancer cells 显示文摘LACOUR S MICHEAU O HAMMANN A 2003Oncogene2003,22,:1
7Antieancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis- inducing ligand-mediated caspase-8 activation and apoptosis显示文摘Laeour S Hammann A Wotawa A 2001Cancer Res2001,61,4:1
8Fas Ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs 显示文摘Micheau O Solary E Hammann A 1999J Biol Chem1999,274,12:1
9Anticancer Agents Sensitize Tumor Cells to Tumor Necrosis Factor-related Apoptosisinducing Ligand-mediated Caspase-8 Activation and Apoptosis显示文摘Lacour S Hammann A Wotawa A 2001Cancer Res2001,61,2:1
10Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis显示文摘Lacour S Hammann A 2001Cancer Rees2001,61,4:1
11Chemotherapy enhances TNF-related apoptosis-inducing ligand DISC assembly in HT29 human colon cancer cells 显示文摘Lacour S Micheau O Hammann A 2003Oncogene2003,22,:1
12Anticancer agents sensitize tumor cells to tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis显示文摘Acour S Hammann A Wotawa A 2001Cancer Res2001,61,4:1
13Anticancer agents sensitize tumor cell sto TRAIL-mediated activation and apoptosis显示文摘Lacour S Hammann A Wotawa A 2001Cancer Res2001,61,4:1
14Chemotherapy enhances TNF-related apoptosis-inducing ligand DISC assembly in HT29 human colon cancer cells 显示文摘Lacour S Micheau O Hammann A 2003Oncogene2003,22,:1
15Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis 显示文摘Lacour S Hammann A Wotawa A 2001Cancer Res2001,61,4:1
16Cisplatin-induced CD95 redistribution into membrane lipid rafts of HT29 human colon cancer cells 显示文摘LACOUR S HAMMANN A GRAZIDE S 2004Cancer Res2004,64,10:1
17Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosls-iuducing ligand-mediated Caspase-8 activation and apoptosisl 显示文摘LACOUR S HAMMANN A WOTAWA A 2001Cancer Res2001,61,4:1
18Fas ligand-independent,FADD mediate activation of the Fas death pathway by anticancer drugs显示文摘Micheau O Solary E Hammann A 0,,12:1
19Surface phenotype and functions of tumor-infiltrating dendritic cells: CD8 expression by a cell subpopulation显示文摘Chaux P Hammann A Martin A 1993Eur J Immunol1993,23,:1
20Sensieization of cancer cells with cytotxic drugs to fas - mediated cytoxiciey 显示文摘Micheau O Solary E Hammann A 1997J Natl Cancer Inst1997,89,11:1
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