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| 1 | Usefulness of adjunctive alphal-adrenergic antagonists after single extracorporeal shock wave lithotripsy session in ureteral stone expulsion显示文摘 | Janane A Hamdoun A Hajji F | 2014 | Can Urol Assoc J2014，8，12： | 1 |
| 2 | The roles of canonical and non-canonical Wnt signaling in human de-differentiated articular chondrocytes显示文摘 | N Sassi L Laadhar M Allouche B Zandieh-Doulabi M Hamdoun J Klein-Nulend S Makni S Sellami | 2014 | Biotechnic & Histochemistry2014，，： | 1 |
| 3 | Emerging contaminants-pesticides,PPCPs,microbial degradation products and natural substances as inhibitors of multixenobiotic defense in aquatic organisms显示文摘 | Smital T Luckenbach T Sauerbom R Hamdoun A M Vega R L Epel D | | 0，，1： | 1 |
| 4 | The sea urchin embryo as a model for studying efflux transporters: roles and energy cost 显示文摘 | EPEL D COLE B HAMDOUN A | 2006 | Marine Environmental Research2006，62，12： | 1 |
| 5 | MCC1019,a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel,potent anticancer candidate显示文摘Polo-like kinase(PLK1) has been identified as a potential target for cancer treatment.Although a number of small molecules have been investigated as PLK1 inhibitors, many of which showed limited selectivity. PLK1 harbors a regulatory domain, the Polo box domain(PBD), which has a key regulatory function for kinase activity and substrate recognition. We report on 3-bromomethylbenzofuran-2-carboxylic acid ethyl ester(designated: MCC1019) as selective PLK1 inhibitor targeting PLK1 PBD. Cytotoxicity and fluorescence polarization-based screening were applied to a library of 1162 drug-like compounds to identify potential inhibitors of PLK1 PBD. The activity of compound MC1019 against the PLK1 PBD was confirmed using fluorescence polarization and microscale thermophoresis.This compound exerted specificity towards PLK1 over PLK2 and PLK3. MCC1019 showed cytotoxic activity in a panel of different cancer cell lines. Mechanistic investigations in A549 lung adenocarcinoma cells revealed that MCC1019 induced cell growth inhibition through inactivation of AKT signaling pathway, it also induced prolonged mitotic arrest—a phenomenon known as mitotic catastrophe, which is followed by immediate cell death via apoptosis and necroptosis. MCC1019 significantly inhibited tumor growth in vivo in a murine lung cancer model without affecting body weight or vital organ size, and reduced the growth of metastatic lesions in the lung. We propose MCC1019 as promising anti-cancer drug candidate. | Sara Abdelfatah Angela Berg Qi Huang Li Jun Yang Sami Hamdoun Anette Klinger Henry J.Greten Edmond Fleischer Thorsten Berg Vincent K.W.Wong Thomas Efferth | 2019 | Acta Pharmaceutica Sinica B2019，9，5： | 1 |
| 6 | Tolerance to biodegraded crude oil in marine invertebrate embryos and larvae is associated with expression of a multixenobiotic resistance transporter显示文摘 | HAMDOUN A M GRIFFIN F J | 2002 | Aquatic Toxicology2002，61，： | 1 |
| 7 | Measurement of Complex Permittivity of Adhesive Materials Using A Short Open- Ended Coaxial Line Probe显示文摘 | Mahmoud Hamdoun | 2004 | Journal of Microwaves and Optoelectronics2004，10，3： | 1 |
| 8 | Usefulness of adjunctive alphal-adrenergic antagonists after single extracorporeal shock wave lithotripsy session in ureteral stone expulsion显示文摘 | Janane A Hamdoun A Hajji F | 2014 | Can Urol Assoc J2014，8，12： | 1 |
| 9 | Numerical simulation of UV LEDs with GaN and BGaN single quantum well显示文摘The objective of this work is to simulate a single quantum well ultraviolet light emitting diode(LED) based on AlGaN/GaN/AlGaN and AlGaN/BGaN/AlGaN, by using TCAD Silvaco simulator. The first structure has a GaN quantum well taken between two layers, of n-AlGaN and p-AlGaN. The second one has a BGaN quantum well instead of GaN. We fix the concentration of the boron in BGaN to only 1% and we vary the thickness of GaN and BGaN quantum well layer from 7 to 20 nm, for the two structures. As results, we obtain respectively for GaN-LED and BGaN-LED, a maximum current of 0.52 and 0.27 mA, a maximum power spectral density of 1.935 and 6.7 W cm^(-1) eV^(-1), a maximum spontaneous emission of 3.34 × 10^(28) and 3.43 × 10^(28) s^(-1) cm^(-3) eV^(-1), and a maximum Light output power of 0.56 and 0.89 mW. | Asma Belaid Abdelkader Hamdoune | 2019 | Journal of Semiconductors2019，40，3： | 0 |
| 10 | Information security through controlled quantum teleportation networks显示文摘Information security is the backbone of current intelligent systems,such as the Internet of Things(IoT),smart grids,and Machine-to-Machine(M2M)communication.The increasing threat of information security requires new models to ensure the safe transmission of information through such systems.Recently,quantum systems have drawn much attention since they are expected to have a significant impact on the research in information security.This paper proposes a quantum teleportation scheme based on controlled multi-users to ensure the secure information transmission among users.Quantum teleportation is an original key element in a variety of quantum information tasks as well as quantum-based technologies,which plays a pivotal role in the current progress of quantum computing and communication.In the proposed scheme,the sender transmits the information to the receiver under the control of a third user or controller.Here,we show that the efficiency of the proposed scheme depends on the properties of the transmission channel and the honesty of the controller.Compared with various teleportation scheme presented recently in the literature,the most important difference in the proposed scheme is the possibility of suspicion about the honesty of the controller and,consequently,taking proper precautions. | Hala Hamdoun Alaa Sagheer | 2020 | Digital Communications and Networks2020，6，4： | 0 |
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