维普期刊资源整合服务平台（V6.5）

112篇 您的检索式：作者名="Halfter"

选中清除导出查看参考文献查看引证文献引用追踪共6页首页上一页第1页下一页末页 /6 跳转

	题名	作者	年代	出处	被引量
1	Collagen/hyaluronan based hydrogels releasing sulfated hyaluronan improve dermal wound healing in diabetic mice via reducing inflammatory macrophage activity显示文摘Sustained inflammation associated with dysregulated macrophage activation prevents tissue formation and healing of chronic wounds.Control of inflammation and immune cell functions thus represents a promising approach in the development of advanced therapeutic strategies.Here we describe immunomodulatory hyaluronan/collagen(HA-AC/coll)-based hydrogels containing high-sulfated hyaluronan(sHA)as immunoregulatory component for the modulation of inflammatory macrophage activities in disturbed wound healing.Solute sHA downregulates inflammatory activities of bone marrow-derived and tissue-resident macrophages in vitro.This further affects macrophage-mediated pro-inflammatory activation of skin cells as shown in skin ex-vivo cultures.In a mouse model of acute skin inflammation,intradermal injection of sHA downregulates the inflammatory processes in the skin.This is associated with the promotion of an anti-inflammatory gene signature in skin macrophages indicating a shift of their activation profile.For in vivo translation,we designed HA-AC/coll hydrogels allowing delivery of sHA into wounds over a period of at least one week.Their immunoregulatory capacity was analyzed in a translational experimental approach in skin wounds of diabetic db/db mice,an established model for disturbed wound healing.The sHA-releasing hydrogels improved defective tissue repair with reduced inflammation,augmented pro-regenerative macrophage activation,increased vascularization,and accelerated new tissue formation and wound closure.	Sophia Hauck Paula Zager Norbert Halfter Elke Wandel Marta Torregrossa Ainur Kakpenova Sandra Rother Michelle Ordieres Susann Räthel Albrecht Berg Stephanie Möller Matthias Schnabelrauch Jan C.Simon Vera Hintze Sandra Franz	2021	Bioactive Materials2021，6，12：	7
2	The Arabidopsis thaliana SOS2 gene encodes a protein kinase that is required for salt tolerance显示文摘	Liu J Ishitani M Halfter U	2000	Proc Natl Acad Sci USA2000，97，7：	1
3	Heparan sulfate proteoglycans are ligands for receptor protein tyrosion phoqhatase显示文摘	Aricescu AR Mckinnell IW Halfter W	2002	Molecular and Cellular Biology2002，22，6：	1
4	Molecular characterization of functional domains in the protein kinase SOS2 that is required for plant salt tolerance显示文摘	Guo Y Ursula Halfter Manabu Ishitani	2001	The Plant Cell2001，13，：	1
5	The Arabid OP sisthaliana SOS2 gene eneodes a Protein kinase that is required for salt tolerance 显示文摘	LIU J P ISHITANI M HALFTER U	2000	Proceedings of the National Academy of Sciences2000，97，7：	1
6	Y-box protein-1is actively secreted through a non-classical pathway and acts as an extracellular mitogen显示文摘	FRYE BC HALFTER S DJUDJAJ S	2009	EMBO Rep2009，10，7：	1
7	The Arabidopsis thaliana SOS2 gene encodes a protein kinase that is required for salt tolerance显示文摘	Liu J Ishitani M Halfter U	2000	Proc Natl Acad Sci USA2000，97，：	1
8	Molecular characterizationof functional domains in the protein kinase SOS2 that is requiredfor plant salt tolerance 显示文摘	GUO Y HALFTER U Zhu J K	2001	Plant Cell2001，13，6：	1
9	The Arabidopsis SOS2 protein kinase physically interacts with and is activated by the calcium-binding protein, SOS3显示文摘	Halfter U Ishitani M Zhu J K	2000	Proceedings of the National Academy of Sciences2000，97，：	1
10	Gene targeting in Arabidopsis thaliana 显示文摘	Halfter U Morris P C Willmitzer L	1992	Mol Genet Genom1992，231，2：	1
11	The Arabidopsis thaliana SOS2 gene encodes a protein kinase that is required for salt tolerance显示文摘	Liu J Ishitani M Halfter U	2000	Proceedings of the National Academy of Sciences2000，97，：	1
12	Interferon gammadependent tyrosine phosphorylation of MEKK4 via Pyk2 is regulated by annexin 11 and SHP2 in keratinocytes显示文摘	Halfter UM Derbyshire ZE Vaillancourt RR	2004	Bio Chem J2004，，：	1
13	SOS3 function in plant salt tolerance requires N-myristoylation and calcium binding显示文摘	Ishitani M Liu J Halfter U	2000	Plant Cell2000，12，：	1
14	Molecular characterization of functional domains in the protein kinase SOS2 that is required for plant salt tolerance显示文摘	Guo Y Halfter U Ishitani M Zhu J K	2001	Plant Cell2001，13，：	1
15	SOS3 function in plant salt tolerance requires N -myristoylation and calcium binding 显示文摘	Ishitani M Liu J Halfter U	2000	Plant Cell2000，12，：	1
16	Flt3 mutations from patients with acute myeloid leukemia induce transforma- tion of 32D cells mediated by the Ras and STAT5 path- ways显示文摘	Mizuki M Fenski R Halfter H	2000	Blood2000，96，12：	1
17	The Arabidopsis thali-ana SOS2 gene encodes a protein kinase that is required for salt tolerance显示文摘	Liu J Ishitani M Halfter U		0，，：	1
18	The Arabidopsis thaliana SOS2 gene encodes a protein kinase that is required for salt tolerace 显示文摘	Liu J Ishitani M Halfter U	2000	Proceedings of National Academy Sciences of the USA2000，97，：	1
19	opticinbinds to heparan and chondroitin sulfate proteoglycans显示文摘	Hindson VJ Gallagher JT Halfter W	2005	Invest Ophthalmol Vis Sci2005，46，：	1
20	The Arabidopsis SOS2 protein kinase physically interacts with and is activated by the calcium-binding protein SOS3显示文摘	HALFTER U ISHITANI M ZHU J K	2000	Proc Natl Acad Sci2000，97，7：	1

返回顶部每页显示：

共6页首页上一页第1页下一页末页 /6 跳转

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

用户提示