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| 1 | Insulin resistance in H pylori infection and its association with oxidative stress显示文摘AIM: To determine the insulin resistance (IR) and oxidative status in H pylori infection and to find out if there is any relationship between these parameters and insulin resistance. METHODS: Fifty-five H pylori positive and 48 H pylori negative patients were enrolled. The homeostasis model assessment (HOMA) was used to assess insulin resistance. Serum total antioxidant capacity (TAC), total oxidant status (TOS) and oxidative stress index (OSI) were determined in all subjects. RESULTS: The total antioxidant capacity was significantly lower in H pylori positive group than in H pylori negative group (1.36 ± 0.33 and 1.70 ± 0.50, respectively; P < 0.001), while the total oxidant status and oxidative stress index were significantly higher in H pylori positive group than in H pylori negative group (6.79 ± 3.40 and 5.08 ± 0.95, and 5.42 ± 3.40 and 3.10 ± 0.92, respectively; P < 0.001). Insulin resistance was significantly higher in H pylori positive group than in H pylori negative group (6.92 ± 3.86 and 3.61 ± 1.67, res- pectively; P < 0.001). Insulin resistance was found to be significantly correlated with total antioxidant capacity (r = -0.251, P < 0.05), total oxidant status (r = 0.365, P < 0.05), and oxidative stress index (r = 0.267, P < 0.05). CONCLUSION: Insulin resistance seems to be associated with increased oxidative stress in H pylori infection. Further studies are needed to clarify the mechanisms underlying this association and elucidate the effectof adding antioxidant vitamins to H pylori eradication therapy on insulin resistance during H pylori infection. | Mehmet Aslan Mehmet Horoz Yasar Nazligul Cengiz Bolukbas F Fusun Bolukbas Sahbettin Selek Hakim Celik Ozcan Erel | 2006 | World Journal of Gastroenterology2006,12,42: | 15 |
| 2 | MPTCP与CMT-SCTP多路径传输协议性能分析显示文摘利用终端的多宿主特性实现多路径传输是因特网协议的一个热点研究问题,MPTCP和CMT-SCTP是目前比较成熟而关键的两个多路径传输协议,但在大规模应用前还需要作大量的性能测试分析研究。在本地测试床环境中,对MPTCP和CMT-SCTP多路径传输实际吞吐量的性能进行对比测试与分析。结果表明MPTCP和CMT-SCTP都能获得吞吐量的提高,但传输调度算法仍然不完善,需要进一步改进。 | 符发 周星 杨雄 Hakim Adhari Erwin P.Rathgeb | 2013 | 计算机工程与应用2013,49,21: | 9 |
| 3 | Pancreatic injury in patients with septic shock: A literature review显示文摘Sepsis and septic shock are life threatening condition associated with high mortality rate in critically-ill patients. This high mortality is mainly related to the inadequacy between oxygen delivery and cellular demand leading to the onset of multiorgan dysfunction. Whether this multiorgan failure affect the pancreas is not fully investigated. In fact, pancreatic injury may occur because of ischemia, overwhelming inflammatory response, oxidative stress, cellular apoptosis and/or metabolic derangement. Increased serum amylase and/or lipase levels are common in patients with septic shock. However, imaging test rarely reveal significant pancreatic damage. Whether pancreatic dysfunction does affect the prognosis of patients with septic shock or not is still a matter of debate. In fact, only few studies with limited sample size assessed the clinical relevance of the pancreatic injury in this group of patients. In this review, we aimed to describe the epidemiology and the physiopathology of pancreatic injury in septic shock patients, to clarify whether it requires specific management and to assess its prognostic value. Our main finding is that pancreatic injury does not significantly affect the outcome in septic shock patients. Hence, increased serum pancreatic enzymes without clinical features of acute pancreatitis do not require further imaging investigations and specific therapeutic intervention. | Anis Chaari Karim Abdel Hakim Kamel Bousselmi Mahmoud Etman Mohamed El Bahr Ahmed El Saka Eman Hamza Mohamed Ismail Elsayed Mahmoud Khalil Vipin Kauts William Francis Casey | 2016 | World Journal of Gastrointestinal Oncology2016,8,7: | 8 |
| 4 | Out of hospital cardiac arrest resuscitation outcome in North India—CARO study显示文摘BACKGROUND: To evaluate the outcome of cardiopulmonary resuscitation(CPR) in out-ofhospital cardiac arrests(OHCA) in India and factors infl uencing the outcome.METHODS: The outcome and related factors like demographics, aspects of the OHCA event, return of spontaneous circulation(ROSC) and survival to discharge, among the 80 adult patients presenting to emergency department experiencing OHCA considered for resuscitation between January 2014 to April 2015, were analyzed, according to the guidelines of the Utstein consensus conference.RESULTS: The survival rate to hospital admission was 32.5%, the survival rate to hospital discharge was 8.8% and with good cerebral performance category(CPC1) neurological status was 3.8%. Majority of OHCA was seen in elderly individuals between 51 to 60 years, predominately in males. Majority of OHCA were witnessed arrests(56.5%) with 1.3% bystander CPR rate, 92.5% arrests occurred at home, 96% presented with initial non-shockable rhythm and 92.5% with presumed cardiac etiology but survival was better in those who experienced OHCA at public place, in witnessed arrests, in patients who had shockable presenting rhythm and in those where CPR duration was ≤20 minutes.CONCLUSION: Witnessed arrests, early initiation of CPR by bystanders, CPR duration ≤20 minutes, initial presenting shockable rhythm, OHCA with non-cardiac etiology are associated with a good outcome. To improve the outcome of CPR and the low survival rates after an OHCA event in India, focused strategies should be designed to set up an emergency medical system(EMS), to boost the rates of bystander CPR and education of the lay public in basic CPR. | Chennappa Kalvatala Krishna Hakim Irfan Showkat Meenakshi Taktani Vikram Khatri | 2017 | World Journal of Emergency Medicine2017,8,3: | 7 |
| 5 | Clinacanthus nutans:a review of the medicinal uses,pharmacology and phytochemistry显示文摘Clinacanthus nutans Lindau is known as snake grass belonging to the Acanlhaceae family.This plant has diverse and potential medicinal uses in traditional herbal medicine for treating skin rashes,insects and snake bites,lesions caused by herpes simplex virus,diabetes,and gout in Malaysia.Indonesia.Thailand and China.Phylochemieal investigations documented the varied contents of bioaclive compounds from litis plant namely flavonoids,glycosides,glycoglyeerolipids.cerebrosides and monoacylmonogalatosylglycerol.The pharmacological experiment proved that various types of extracts and pure compounds from this species exhibited a broad range of biological properties such as anti-inflammatory,antiviral,antioxidant,and anti-diabetic activities.The lindings of toxicity study showed that extracts from this plant did not show any toxicity thus it can be used as strong therapeutic agents for specific diseased conditions.However,further experiments on chemical components and their mode of action showing biological activities are required to elucidate the complete phytochemical profile and assess to confirm their suitability tor future drugs.This review summarizes the medicinal uses,phytochemistry and pharmacology of this plant in order to explore its therapeutic potential and gaps necessitating for prospected research work. | Md.Ariful Alam Sahena Ferdosh Kashif Ghafoor Md.Abdul Hakim Abdul Shukor Juraimi Alfi Khatib Md.Zaidul I.Sarker | 2016 | Asian Pacific Journal of Tropical Medicine2016,9,4: | 7 |
| 6 | 多场景的MPTCP协议性能分析研究显示文摘利用多宿主设备的多个接口实现多路径传输、获取更多的网络吞吐量是因特网协议研究的热点。IETF所关注的MPTCP协议是当前比较成熟、关键的多路径传输协议。为了测试MPTCP在当前已部署的网络环境中的性能,分别在本地测试床、Internet环境测试场景和大规模多宿主系统Nor Net测试床中对MPTCP多路径传输实际吞吐量性能进行了测试和分析,测试结果表明MPTCP相对TCP虽能获得吞吐量的提高,但在非相似带宽链路的场景中其性能仍然不完善,其路径管理和传输调度策略仍需要进一步改进。 | 符发 周星 谭毓银 Thomas Dreibholz Hakim Adhari Erwin P.Rathgeb | 2016 | 计算机工程与应用2016,52,5: | 6 |
| 7 | Limited, local, extracolonic spread of mucinous appendiceal adenocarcinoma after perforation with formation of a malignant appendix-to-sigmoid fistula: Case report and literature review显示文摘A 68-year-old man presented with progressive right lower quadrant abdominal pain and tenderness without rebound tenderness, and with constipation during the prior 9 mo. Abdomino-pelvic computed tomography and magnetic resonance imaging demonstrated a dilated appendix forming a fistula to the sigmoid colon. Open laparotomy revealed a bulky abdominal tumor involving appendix, cecum, and sigmoid, and extending up to adjacent viscera, without ascites or peritoneal implants. The abdominal mass was removed en bloc, including resection of sigmoid colon, cecum(with preservation of ileocecal valve), appendix, right vas deferens, testicular vessels, and minimal amounts of anterior abdominal wall; and shaving off of small parts of the walls of the urinary bladder and small bowel. Gross and microscopic pathologic examination revealed an appendix-to-sigmoid malignant fistula secondary to perforation of mucinous adenocarcinoma of the appendix with minimal local spread(stage T4). However, the surgical margins were clear, all 13 resected lymph nodes were cancer-free, and pseudomyxoma peritonei or peritoneal implants were not present. The patient did well during 1 year of follow-up with no clinical or radiologic evidence of local recurrence, metastases, or pseudomyxoma peritonei despite presenting with extensive stage T4 cancer that was debulked without administering chemotherapy, and despite presenting with malignant appendiceal perforation. This case illustrates the non-aggressive biologic behavior of this low-grade malignancy. The fistula may have prevented free spillage of cancerous cells and consequent distant metastases by containing the appendiceal contents largely within the colon. | Seifeldin Hakim Mitual Amin Mitchell S Cappell | 2016 | World Journal of Gastroenterology2016,22,38: | 4 |
| 8 | Modeling of bentonite/sepiolite plastic concrete compressive strength using artificial neural network and support vector machine显示文摘Plastic concrete is an engineering material,which is commonly used for construction of cut-offwalls to prevent water seepage under the dam.This paper aims to explore two machine learning algorithms including artificial neural network (ANN)and support vector machine (SVM)to predict the compressive strength of bentonite/sepiolite plastic concretes.For this purpose,two unique sets of 72 data for compressive strength of bentonite and sepiolite plastic concrete samples (totally 144 data)were prepared by conducting an experimental study.The results confirm the ability of ANN and SVM models in prediction processes.Also,Sensitivity analysis of the best obtained model indicated that cement and silty clay have the maximum and minimum influences on the compressive strength,respectively.In addition, investigation of the effect of measurement error of input variables showed that change in the sand content (amount)and curing time will have the maximum and minimum effects on the output mean absolute percent error (MAPE)of model, respectively.Finally,the influence of different variables on the plastic concrete compressive strength values was evaluated by conducting parametric studies. | Ali Reza GHANIZADEH Hakime ABBASLOU Amir Tavana AMLASHI Pourya ALIDOUST | 2019 | Frontiers of Structural and Civil Engineering2019,13,1: | 3 |
| 9 | Geochemical and stable isotopic studies of Gulf of Suez’s hot springs,Egypt显示文摘The Gulf of Suez region is one of the most interesting geothermal areas in Egypt because of the high temperatures of its springs.The eastern and western shores of the Gulf of Suez are characterized by superficial thermal manifestations including a cluster of hot springs with varied temperatures.Variations of deuterium and oxygen-18 concentrations in thermal waters have been used to aid in describing the source of recharge in the Gulf of Suez hot springs.Isotope and geochemical data for the Gulf of Suez thermal waters suggest that recharge to the hot springs may not be entirely from the Gulf of Suez water,but possibly from the meteoric water that comes from areas of higher altitude surrounding the hot springs. | Mohamed Abdel Zaher Hakim Saibi Sachio Ehara | 2012 | Chinese Journal Of Geochemistry2012,31,2: | 3 |
| 10 | Iterative Bayesian Monte Carlo for nuclear data evaluation显示文摘In this work,we explore the use of an iterative Bayesian Monte Carlo(iBMC)method for nuclear data evaluation within a TALYS Evaluated Nuclear Data Library(TENDL)framework.The goal is to probe the model and parameter space of the TALYS code system to find the optimal model and parameter sets that reproduces selected experimental data.The method involves the simultaneous variation of many nuclear reaction models as well as their parameters included in the TALYS code.The‘best’model set with its parameter set was obtained by comparing model calculations with selected experimental data.Three experimental data types were used:(1)reaction cross sections,(2)residual production cross sections,and(3)the elastic angular distributions.To improve our fit to experimental data,we update our‘best’parameter set—the file that maximizes the likelihood function—in an iterative fashion.Convergence was determined by monitoring the evolution of the maximum likelihood estimate(MLE)values and was considered reached when the relative change in the MLE for the last two iterations was within 5%.Once the final‘best’file is identified,we infer parameter uncertainties and covariance information to this file by varying model parameters around this file.In this way,we ensured that the parameter distributions are centered on our evaluation.The proposed method was applied to the evaluation of p+^(59)Co between 1 and 100 MeV.Finally,the adjusted files were compared with experimental data from the EXFOR database as well as with evaluations from the TENDL-2019,JENDL/He-2007 and JENDL-4.0/HE nuclear data libraries. | Erwin Alhassan Dimitri Rochman Alexander Vasiliev Mathieu Hursin Arjan JKoning Hakim Ferroukhi | 2022 | Nuclear Science and Techniques2022,33,4: | 3 |
| 11 | Two case reports of acute upper gastrointestinal bleeding from duodenal ulcers after Roux-en-Y gastric bypass surgery: Endoscopic diagnosis and therapy by single balloon or push enteroscopy after missed diagnosis by standard esophagogastroduodenoscopy显示文摘The diagnosis and opportunity for endoscopic therapy of gastric or duodenal lesions may be missed at esophagogastroduodenoscopy(EGD) because of technical difficulty in intubating at EGD the postoperatively excluded stomach and proximal duodenum in patients status post Roux-en-Y gastric bypass(RYGB). Two cases are reported of acute upper gastrointestinal bleeding 10 or 11 years status postRYGB, performed for morbid obesity, in which the EGD was non-diagnostic due to failure to intubate the excluded stomach and proximal duodenum, whereas subsequent push enteroscopy or single balloon enteroscopy were diagnostic and revealed 4-cm-wide or 5-mm-wide bulbar ulcers and even permitted application of endoscopic therapy. These case reports suggest consideration of push enteroscopy, or single balloon enteroscopy, where available, in the endoscopic evaluation of acute UGI bleeding in patients status post RYGB surgery when the EGD was non-diagnostic because of failure to intubate these excluded segments. | Seifeldin Hakim Srinivas R Rami Reddy Mihaela Batke Gregg Polidori Mitchell S Cappell | 2017 | World Journal of Gastrointestinal Endoscopy2017,9,10: | 3 |
| 12 | Assessment of ship manoeuvrability by using a coupling between a nonlinear transient manoeuvring model and mathematical programming techniques显示文摘In this paper,a numerical method based on a coupling between a mathematical model of nonlinear transient ship manoeuvring motion in the horizontal plane and Mathematical Programming(MP)techniques is proposed.The aim of the proposed procedure is an efficient estimation of optimal ship hydrodynamic parameters in a dynamic model at the early design stage.The proposed procedure has been validated through turning circle and zigzag manoeuvres based on experimental data of sea trials of the 190 000-dwt oil tanker.Comparisons between experimental and computed data show a good agreement of overall tendency in manoeuvring trajectories. | TRAN KHANH Toan OUAHSINE Abdellatif NACEUR Hakim EL WASSIFI Karima | 2013 | Journal of Hydrodynamics2013,25,5: | 3 |
| 13 | Effect of Al Doping on Structural, Electrical, Optical and Photoluminescence Properties of Nano-Structural ZnO Thin Films显示文摘The nano-structural Al-doped ZnO thin films of different morphologies deposited on glass substrate were successfully fabricated at substrate temperature of 350 C by an inexpensive spray pyrolysis method. The structural, electrical, optical and photoluminescence properties were investigated. X-ray diffraction study revealed the crystalline wurtzite (hexagonal) structure of the films with nano-grains. Scanning electron mi- croscopy (SEM) micrographs indicated the formation of a large variety of nano-structures during film growth. The spectral absorption of the films occurred at the absorption edge of ~410 nm. In the present study, the optical band gap energy 3.28 eV of ZnO decreased gradually to 3.05 eV for 4 mol% of Al doping. The deep level activation energy decreased and carrier concentrations increased substantially with increasing doping. Exciting with the energy 3.543 eV (λ=350 nm), a narrow and a broad characteristic photoluminescence peaks that correspond to the near band edge (NBE) and deep level emissions (DLE), respectively emerged. | M. Mozibur Rahman M.K.R. Khan M. Rafiqul Islam M.A. Halim M. Shahjahan M.A. Hakim Dilip Kumar Saha Jasim Uddin Khan | 2012 | Journal of Materials Science & Technology2012,28,4: | 3 |
| 14 | Bitcoin pricing: impact of attractiveness variables显示文摘The research seeks to contribute to Bitcoin pricing analysis based on the dynamics between variables of attractiveness and the value of the digital currency.Using the error correction model,the relationship between the price of the virtual currency,Bitcoin,and the number of Google searches that used the terms bitcoin,bitcoin crash and crisis between December 2012 and February 2018 is analyzed.The study also applied the same analysis to prices of Bitcoin denominated in different sovereign currencies traded during the same period.The Johansen(J Econ Dyn Control 12:231-254,1988)test demonstrates that the price and number of searches on Google for the first two terms are cointegrated.This research indicates that there are strong short-term and long-term dynamics among attractiveness factors,suggesting that an increase in worldwide interest in Bitcoin is usually preceded by a price increase.In contrast,an increase in market mistrust over a collapse of the currency,as measured by the term bitcoin crash,is followed by a fall in price.Intense world economic crisis events appear to have a strong impact on interest in the virtual currency.This study demonstrates that during a worldwide crisis Bitcoin becomes an alternative investment,increasing its price.Based on it,bitcoin may be used as a safe haven by the financial market and its intrinsic characteristics might help the investors and governments to find new mechanisms to deal with monetary transactions. | Rodrigo Hakim das Neves | 2020 | Financial Innovation2020,6,1: | 3 |
| 15 | Low-level laser therapy enhances the number of osteocytes in calvaria bone defects of ovariectomized rats显示文摘Background : Osteoporosis can make bone repair difficult. Low-level laser therapy( LLLT) has been shown to be a promising tool for bone neoformation. This study aimed to analyze the effect of LLLT on calvaria bone defects of ovariectomized rats using stereology. Methods : Fifty-four Wistar rats were subjected to bilateral ovariectomy, and bone defects were created in calvaria after 150 days. The animals were divided into nine groups(n = ?6 per group), and 24 hours after the bone defects were created they received three, six or 12 sessions of LLLT at 0, 20 or 30 J/cm 2, using a 780-nm low-intensity GaAlAs laser. One-way ANOVA followed by Tukey ' s post hoc test was used for data processing. A difference of P < 0.05 was considered statistically significant. The parameters evaluated were osteocyte density( Nv_(ost)), total osteocyte number( Nto ost), trabecular surface density( Sv_t), and trabecular surface area( Sa_t). Results : Data obtained showed that Nto ost, Sv t, and Sa t in group G2 rats were significantly different from G1(0 J/cm^2)( P < 0.05). Compared to group G4, G5 presented higher values for the parameters Sv t and Sa t, and G6 presented significantly higher values for almost all the analyzed parameters( Nv _(ost), Nto_(ost), Sv_t, and Sa t)( P < 0.05). Compared to group G7, G8 showed a higher value only for the parameter Sa t, and G9 showed significantly higher values for parameters Nv ost, Nto ost, Sv_t, and Sa_t. Conclusion : We conclude that LLLT stimulated bone neoformation and contributed to an increase in the total number of osteocytes, especially with a laser energy density of 30 J/cm^2 given for six and 12 sessions. | Priscilla Hakime Scalize Luiz Gustavo de Sousa Lígia Maria Napolitano Goncalves Dimitrius Leonardo Pitol Marcelo Palinkas Antonio Augusto Coppi Mariah Acioli Righeti Vitória Ricardo Karina Fittipaldi Bombonato-Prado Simone Cecílio Hallak Regalo Selma Siessere | 2019 | Animal Models and Experimental Medicine2019,2,1: | 2 |
| 16 | Comparison between the SAPIEN S3 and the SAPIEN XT transcatheter heart valves:A single-center experience显示文摘AIM To investigate the clinical outcomes of transcatheter aortic valve implantation(TAVI) with the SAPIEN 3 transcatheter heart valve(S3-THV) vs the SAPIEN XT valve(XT-THV).METHODS We retrospectively analyzed 507 patients that underwent TAVI with the XT-THV and 283 patients that received the S3-THV at our institution between March 2010 and December 2015.RESULTS Thirty-day mortality(3.5% vs 8.7%:OR=0.44,P=0.21) and 1-year mortality(25.7% vs 20.1%,P=0.55) were similar in the S3-THV and the XT-THV groups.The rates of both major vascular complication and paravalvular regurgitation(PVR)>1 were almost 4 times lower in the S3-THV group than the XT-THV group(major vascular complication: 2.8% vs 9.9%,P<0.0001:PVR>1: 2.4% vs 9.7%,P<0.0001).However,the rate of new pacemaker implantation was almost twice as high in the S3-THV group(17.3% vs 9.8%,P=0.03).In the S3 group,independent predictors of new permanent pacemaker were pre-procedural RBBB(OR=4.9:P=0.001),pre-procedural PR duration(OR=1.14,P=0.05) and device lack of coaxiality(OR=1.13:P=0.05) during deployment.CONCLUSION The S3-THV is associated to lower rates of major vascular complications and PVR but higher rates of new pacemaker compared to the XT-THV.Sub-optimal visualization of the S3-THV in relation to the aortic valvular complex during deployment is a predictor of new permanent pacemaker. | Fadi J Sawaya Marco Spaziano Thierry Lefèvre Andrew Roy Phillippe Garot Thomas Hovasse Antoinette Neylon Hakim Benamer Mauro Romano Thierry Unterseeh Marie-Claude Morice Bernard Chevalier | 2016 | World Journal of Cardiology2016,8,12: | 2 |
| 17 | Pneumomediastinum, pneumorachis, subcutaneous emphysema: An unusual complication of leukemia in a child显示文摘Pneumorrhachis(PR), or epidural emphysema, denotes the presence of air in the spinal epidural space. It can be associated with a variety of etiologies, including trauma; recent iatrogenic manipulations during surgical, anesthesiological and diagnostic interventions;malignancy and its associated therapy. It usually represents an asymptomatic epiphenomenon but also can be symptomatic by itself, as well as by its underlying pathology, and rarely can be fatal. The pathogenesis and etiology of PR are varied and can sometimes be a diagnostic challenge. As such, there are no standard guidelines for the management of symptomatic PR and its treatment is often individualized. Here, we present a case of a 14-year-old boy treated for leukemia who developed this complication and whether chemotherapy related or not, it proved to be fatal for him. To our knowledge, this is the first case in the literature of this complication with acute lymphoblastic leukemia. | Hakim Irfan Showkat Aleem Jan Arif Hussain Sarmast Gull Mohammad Bhat Basharat Mujtaba Jan Yasir Bashir | 2013 | World Journal of Clinical Cases2013,1,7: | 2 |
| 18 | Accuracy of high‐frequency catheter‐based endoscopic ultrasonography according to the indications for endoscopic treatment of early gastric cancer显示文摘 | Gwang HaKim Do YounPark MitsuhiroKida Dae HwanKim Tae YongJeon Hyun JeongKang Dong UkKim Cheol WoongChoi Bong EunLee JeongHeo Geun AmSong | 2010 | Journal of Gastroenterology and Hepatology2010,,3: | 2 |
| 19 | Manganese superoxide dismutase expression in endothelial progenitor cells accelerates wound healing in diabetic mice显示文摘 | Marrotte Eric J Chen Dan-Dan Hakim Jeffrey S Chen Alex F | 2010 | Journal of Clinical Investigation2010,,12: | 2 |
| 20 | Prevalence of Barrett's esophagus in patients with moderate to severe erosive esophagitis显示文摘AIM: To investigate the proportion of patients with moderate-severe erosive esophagitis (EE) who will have Barrett's esophagus (BE) after healing of inflammation. METHODS: Patients with EE of Los Angeles (LA) class B, C and D who underwent follow-up endoscopy documenting complete mucosal healing. RESULTS: A total of 86/169 patients were suspected of having BE (38 before healing and 48 after healing of EE) and, 46/86 eventually had the histological confirmation. At index esophago-gastro-duodenoscopy (EGD), BE was suspected in 38/169 (22%), and ultimately, histologically confirmed in 20 of these. In 11 patients where biopsies were performed in the presence of inflammation, BE was detected in 2 and missed in 5 (including 2 dysplasias). In 131/169 patients (77.5%), BE was not suspected at index EGD. After healing of EE though, 48 patients had suspicion of BE who underwent biopsies, and in 26 of these histology was positive for BE. The length of inflammation had a linear correlation with the length of BE (P = 0.01). Out of multiple variables to predict BE, only the suspicion at index endoscopy was statistically significant (P = 0.01). CONCLUSION: BE was seen in 46/169 (27%) patients with EE of LA class B, C and D. The length of EE can predict the length of underlying BE segment.Even when suspected, BE and associated dysplasia can be missed in the presence of inflammation; therefore, repeat evaluation should be considered after complete healing of esophagitis. | Nooman Gilani Richard D Gerkin Francisco C Ramirez Shahina Hakim Adam C Randolph | 2008 | World Journal of Gastroenterology2008,14,22: | 2 |