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| 1 | 美国临床生化科学院检验医学实践指南:睾丸、前列腺、结直肠、乳腺及卵巢癌肿瘤标志物的应用显示文摘经美国临床生化科学院(NCAB)授权,由鄢盛恺教授组织学者、专家翻译审定2009年NCAB检验医学实践指南:睾丸、前列腺、结直肠、乳腺及卵巢癌中肿瘤标志物的应用单行本(Catharine M.Sturgeon教授和Eleftherios P.Diaman-dis教授编辑)。该指南包含第1至6章共6部分内容,参加指南制订的专家阵容强大,分别从临床及检验角度对睾丸、前列腺、结直肠、乳腺及卵巢癌中肿瘤标志物的检测与临床应用方面的问题进行了详细阐述与说明,是目前国内外在肿瘤实验诊断方面的纲领性应用文件。不仅适合广大检验人员、临床医护人员学习使用,也非常适合相关仪器试剂生产厂商研发应用。本指南由刘洋、薛丽、林文涛、李江、梁红艳、顾兵、潘世扬、郑磊等翻译,姜晓峰、沈文梅、田亚平、鄢盛恺审校,最后由鄢盛恺统稿审定。本指南的翻译出版,不仅有助于我国检验人员和医护人员合理的检测和应用睾丸、前列腺、结直肠、乳腺及卵巢癌肿瘤标志物,对我国检验医学指南的编写与应用也有一定的借鉴作用。本刊特在本期刊发,以飨广大读者。 | 鄢盛恺 Ulf-Hkan Stenman Rolf Lamerz Leendert H.Looijenga Nils Brünner Michael J.Duffy Caj Haglund Mads Holten-Andersen Hans JФrgen Nielsen Francisco J.Esteva Nadia Harbeck Daniel F.Hayes Rafael Molina Daniel W.Chan Robert C.Bast Jr Ie-Ming Shih Lori J.Sokoll Gyrgy Slétormos 刘洋 梁红艳 姜晓峰 田亚平 薛丽 林文涛 顾兵 潘世扬 沈文梅 郑磊 李江 | 2012 | 临床检验杂志2012，30，2： | 32 |
| 2 | Carbonic anhydrase enzymes Ⅱ, Ⅶ, Ⅸ and Ⅻ in colorectal carcinomas显示文摘AIM To investigate expression of four alpha-carbonic anhydrases(CAs) in colorectal carcinomas(CRC) and compare the results with patients' survival.METHODS Colorectal carcinoma samples from 539 CRC patients and control tissues were arranged as tissue microarrays and analyzed with antibodies against CA Ⅱ, CA Ⅶ, CA Ⅸ, and CA Ⅻ. Intensity and extent of staining were both scored from 0 to 3 in each sample. These enzyme expression levels were then correlated to patients' survival and clinicopathological parameters, which were tumor differentiation grade and stage, site of tumor, patients' age, and gender. Kaplan-Meier analysis and Cox regression hazard ratio model were used to analyze survival data. RESULTS CA Ⅱ and CA Ⅻ staining intensities correlated with patients' survival in that higher expression indicated poorer prognosis. In Cox regression analysis one unit increase in the CA Ⅱ intensity increased the hazard ratio to 1.19 fold(CI: 1.04-1.37, P = 0.009). A significant correlation was also found when comparing CA Ⅻ staining intensity with survival of CRC patients(HR = 1.18, 95%CI: 1.01-1.38, P = 0.036). The extent of CA Ⅻ immunostaining did not correlate to the patients' survival(P = 0.242, Kaplan-Meier analysis). A significant interaction between age group and extent of the CA Ⅱ staining was found. Increased extent of CA Ⅱ had a significant hazard ratio among patients 65 years and older(1.42, 95%CI: 1.16-1.73, P = 0.0006). No correlations were found between CA Ⅶ(intensity P = 0.566, extent P = 0.495, Kaplan-Meier analysis), or CA Ⅸ(intensity P = 0.879, extent P = 0.315, KaplanMeier analysis) immunostaining results and survival, or the other parameters. CONCLUSION The present findings indicate that CA Ⅱ and CA Ⅻ could be useful in predicting survival in CRC. | Pia Viikil? Antti J Kivel? Harri Mustonen Selja Koskensalo Abdul Waheed William S Sly Jaromir Pastorek Silvia Pastorekova Seppo Parkkila Caj Haglund | 2016 | World Journal of Gastroenterology2016，22，36： | 3 |
| 3 | Effects of fish oil alone and combined with long chain (n-6) fatty acids on some coronary risk factors in male subjects显示文摘 | Haglund O Wallin R Wretling S | 1998 | J Nutr Bio- chem1998，9，11： | 1 |
| 4 | IMPDH activity in thiopurine-treated patients with inflammatory bowel disease - relation to TPMT activity and metabolite concentrations 显示文摘 | Haglund S Taipalensuu J Peterson C | 2008 | Br J Clin Phar- macol2008，65，1： | 1 |
| 5 | Pulmonary enflostatin perinatally and in lung injury of the newborn infant显示文摘 | Joakim J Andersson S Haglund C | 2007 | Pediatrics2007，119，1： | 1 |
| 6 | Selective pressurized liquid extraction of polychlorinated dibenzo-p-dioxins, dibenzofurans and dioxin-like polychlorinated biphenyls from food and feed samples 显示文摘 | Wiberg K Sporting S Haglund P Bjorklund E | 2007 | Journal of Chromatography A2007，1138，12： | 1 |
| 7 | Swedish air travellers and voluntary carbon offsets: Towards the co-creation of environmental value? 显示文摘 | Gossling S Haglund L Kallgren H | 2009 | Current Issues in Tourism2009，12，1： | 1 |
| 8 | Effects of fish oil alone and combined with long-chain (n-6) fatty acids on some coronary risk factors in male subjects显示文摘 | Haglund O Wallin R Wretling S | 1998 | J Nutr Biochem1998，，9： | 1 |
| 9 | Frequency of serious complications after surgery for snoring and sleep apnea显示文摘 | Franklin KA Haglund B Axelsson S | 2011 | Acta Otolaryngol2011，131，3： | 1 |
| 10 | Wetted wall cyclones for bioaerosol sampling显示文摘 | McFarland A R Haglund J S King M D | 2010 | Aerosol Science and Technology2010，44，4： | 1 |
| 11 | Low-grade glio-mas associated with intractable epilepsy: seizure outcomeutilizing electrocorticography during tumor resection 显示文摘 | Berger MS Ghatan S Haglund MM | 1993 | JNeurosurg1993，79，： | 1 |
| 12 | The effects of fresh water on the redistribution of uranium in carbonate sediments显示文摘 | Haglund D Sf Friedman G M Miller D S | 1969 | Journal of Sedimentary Petrology1969，39，4： | 1 |
| 13 | Expression of p53 protein as aprognostic factor in patients with gastric cancer显示文摘 | VICTORZON M NORDLING S HAGLUND C | 1996 | Eur J Cancer1996，32，： | 1 |
| 14 | COX-2 is associated with proliferation and apoptosis markers and serves as an independent prognostic factor in gastric cancer显示文摘 | Mrena J Wiksten J P Kokkola A Nordling S Ristim-ki A Haglund C | 2010 | Tumor Biol2010，31，： | 1 |
| 15 | Does Helicobacter pylori in the gastric stump increase the cancer risk after certain reconstmcifontypes?显示文摘 | Leioven M Nordling S Haglund C | 1997 | Anticancer Res1997，17，： | 1 |
| 16 | Simultaneous extraction and fractionation of polycyclic aromatic hydrocarbons and their oxygenated derivatives in soil using selective pressurized liquid extraction显示文摘 | Lundstedt S Haglund P Oberg L | | 0，，： | 1 |
| 17 | Deletion of 11q23 and Cyelin D1 overexpression are frequent aberrations in parathyroid adenomas 显示文摘 | Hemmer S Wasenius V Haglund C | 2001 | Am J Pathol2001，158，4： | 1 |
| 18 | Cortical localization of temporal lobe language sites in patients with gliomas 显示文摘 | Haglund M M Berg M S Lettich E | 1994 | Neurosurgery1994，34，4： | 1 |
| 19 | Identification and Quantification of Polybrominated Diphenylethers and Methoxy - polybrominated Diphenylethers in Baltic Biota显示文摘 | Haglund PS Zook DR Buser H - S | 1997 | Environ Sci Technol1997，31，： | 1 |
| 20 | Identification and quantification of polybrominated diphenyl ethers and methoxy-polybrominated diphenyl ethers in Baltic biota显示文摘 | Haglund P S Zook D R Buser H R | 1997 | Environmental Science&Technology1997，31，11： | 1 |
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