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3篇 您的检索式:作者名="HUI Ru Tai"
    题名 作者 年代 出处 被引量
1Cancer stem‐like cell properties are regulated by EGFR / AKT /β–catenin signaling and preferentially inhibited by gefitinib in nasopharyngeal carcinoma显示文摘Lei Ma Gong Zhang Xiao‐Bo Miao Xu‐Bin Deng Yue Wu Ying Liu Zhi‐Ru Jin Xi‐Qing Li Qiu‐Zhen Liu Du‐Xin Sun Joseph R. Testa Kai‐Tai Yao Guang‐Hui Xiao 2013FEBS J2013,,9:1
2Prognostic Values of Serum Chloride and Sodium Levels in Patients with Three-vessel Disease显示文摘Objective Identification of new risk factors is needed to improve prediction of adverse outcomes in patients with three-vessel disease(TVD). The present study aimed to evaluate the prognostic values of serum chloride and sodium levels in patients with TVD. Methods We used data from a prospective cohort of consecutive patients with angiographically confirmed TVD. The primary endpoint was all-cause death. Cox proportional hazard regression was used to analyze the relationship of serum chloride and sodium levels with long-term outcomes of TVD patients. Results A total of 8,318 participants with available serum chloride and sodium data were included in this analysis. At baseline, patients in the low tertiles group of serum chloride level(≤ 102.0 mmol/L) or serum sodium level(≤ 139.0 mmol/L) had more severe disease conditions. During a median follow-up of 7.5-year, both low serum chloride level and low serum sodium level were found to be associated with an increased risk for mortality in univariate analysis. However, when both parameters were incorporated into a multivariate model, only low serum sodium level remained to be an independent predictor of all-cause death(hazard ratio: 1.16, 95% confidence interval: 1.01-1.34, P = 0.041). Modest but significant improvement of discrimination was observed after incorporating serum sodium level into the Synergy between percutaneous coronary intervention(PCI) with Taxus and Cardiac Surgery score. Conclusion Serum sodium level is more strongly associated with long-term outcomes of TVD patients compared with serum chloride level. Low serum sodium level is an independent risk factor for mortality, but only provides modest prognostic information beyond an established risk model.ZHANG Ce WANG Dong HOU Bing Jie JIANG Lin XU Lian Jun TIAN Jian ZHAO Yan Yan ZHAO Xue Yan FENG Xin Xing ZHANG Yin SUN Kai XU Bo ZHAO Wei HUI Ru Tai GAO Run Lin LOU Hui Ling YUAN Jin Qing SONG Lei 2019Biomedical and Environmental Sciences2019,32,4:1
3Novel Phosphonoacetic Acid Derivatives.Synthesis of N-(Ethoxycarbonylmethylphosphonyl)-α-Amino Esters and-α-Amino Phosphonic Acid Esters and Their Bioactivities显示文摘A series of novel phosphonoacetic acid derivatives, N-(ethoxycarbonylmethy-ethoxyphosphonyl)-α-amino acid esters and α-amino phosphonates, were synthesized via the reaction of the corresponding phosphonyl chloride with amino acid ester hydrochlorides or amino phosphonates in the presence of a base. The preliminary bioassay shows that some compounds show significant anti-viral activity against tobacco mosaic virus (TMV)Hui Ying LI Kang Tai REN Ru Yu CHEN(Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071) 1997Chinese Chemical Letters1997,8,12:0
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