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| 1 | Archaeological records of Dadiwan in the past 60 ka and the origin of millet agriculture显示文摘This paper reports the recent excavation of Unit Dadiwan06 at the Dadiwan site in Qin’an County, Gansu.A 65 ka chronological framework is established for Dadiwan06 on the basis of absolute dating (AMS 14C and OSL), stratigraphy, climate change events and archaeology.Artifact distributions reveal patterns of human behavioral variation and adaptation over the past 60 ka, from primitive hunting and gathering to advanced hunting and gathering, to primitive Neolithic agriculture, and finally to advanced Neolithic agriculture. | ZHANG DongJu CHEN FaHu BETTINGER R L BARTON L JI DuXue MORGAN C WANG Hui CHENG XiaoZhong DONG GuangHui GUILDERSON T P ZHAO Hui | 2010 | Chinese Science Bulletin2010，55，16： | 6 |
| 2 | SPSBl-mediated HnRNP A1 alternative splicing and cell ubiquitylation regulates migration in EGF signaling显示文摘细胞外的信号被显示了影响拼接的其他的 pre-mRNA;然而,分子的机制和导致信号的拼接的规定的生物意义仍然保持大部分未知。这里,我们报导那个表皮的生长因素(EGF ) 通过一个著名拼接管理者的 ubiquitylation 导致拼接的变化, hnRNP A1。EGF 发信号 upregulates 一个 E3 ubiquitin (Ub ) ligase 适配器,敏捷的包含域的 SOCS 盒子蛋白质 1 (SPSB1 ) ,它结合离氨酸 29 连接 polyUb 链到 hnRNP A1 上的成员 Elongin B/C-Cullin 建筑群。重要地, hnRNP A1 的 SPSB1 和 ubiquitylation 在驾驶 EGF 的房间移植有一个关键角色。机械学地,和 SR 蛋白质 kinases (SRPK ) 的激活的 hnRNP A1 的导致 EGF 的 ubiquitylation 导致拼接的 Rac1 的 upregulation isoform, Rac1b,支持房间活动性。这些调查结果解开在蛋白质 ubiquitylation 并且在 EGF/EGF 受体发信号的其他的拼接之间的新奇串音,并且在 modulating 房间移植识别新 EGF/SPSB1/hnRNP A1/Rac1 轴,它可以为癌症治疗有重要含意。 | Feng Wang Xing Fu Peng Chen Ping Wu Xiaojuan Fan Na Li Hong Zhu Ting-Ting Jia Hongbin Ji Zefeng Wang Catherine C L Wong Ronggui Hu Jingyi Hui | 2017 | Cell Research2017，27，4： | 5 |
| 3 | Celiac disease serology in patients with different pretest probabilities: Is biopsy avoidable?显示文摘AIM: To establish the diagnostic performance of sev-eral serological tests, individually and in combination, for diagnosing celiac disease (CD) in patients with different pretest probabilities, and to explore potential se- rological algorithms to reduce the necessity for biopsy. METHODS: We prospectively performed duodenal biopsy and serology in 679 adults who had either high risk (n = 161) or low risk (n = 518) for CD. Blood samples were tested using six assays (enzyme-linked immunosorbent assay) that detected antibodies to tissue transglutaminase (tTG) and deamidated gliadin peptide (DGP). RESULTS: CD prevalence was 39.1% in the high-risk population and 3.3% in the low-risk group. In high-risk patients, all individual assays had a high diagnostic efficacy [area under receiving operator characteristic curves (AU ROC): 0.968 to 0.999]. In contrast, assays had a lower diagnostic efficacy (AU ROC: 0.835 to 0.972) in the low-risk group. Using assay combinations, it would be possible to reach or rule out diagnosis of CD without biopsy in 92% of cases in both pretest populations. We observed that the new DGP/tTG Screen assay resulted in a surplus compared to more conventional assays in any clinical situation. CONCLUSION: The DGP/tTG Screen assay could be considered as the best initial test for CD. Combinations of two tests, including a DGP/tTG Screen, might be able to diagnose CD accurately in different clinical scenarios making biopsy avoidable in a high proportion of subjects. | Emilia Sugai María L Moreno Hui J Hwang Ana Cabanne Adriana Crivelli Fabio Nach-man Horacio Vázquez Sonia Niveloni Julio Argonz Roberto Mazure Graciela La Motta María E Caniggia Edgardo Smecuol Néstor Chopita Juan C Gómez Eduardo Maurińo Julio C Bai | 2010 | World Journal of Gastroenterology2010，16，25： | 4 |
| 4 | Femtojoule electro-optic modulation using a silicon– organic hybrid device显示文摘Energy-efficient electro-optic modulators are at the heart of short-reach optical interconnects,and silicon photonics is considered the leading technology for realizing such devices.However,the performance of all-silicon devices is limited by intrinsic material properties.In particular,the absence of linear electro-optic effects in silicon renders the integration of energy-efficient photonic–electronic interfaces challenging.Silicon–organic hybrid(SOH)integration can overcome these limitations by combining nanophotonic silicon waveguides with organic cladding materials,thereby offering the prospect of designing optical properties by molecular engineering.In this paper,we demonstrate an SOH Mach–Zehnder modulator with unprecedented efficiency:the 1-mm-long device consumes only 0.7 fJ bit^(-1) to generate a 12.5 Gbit s^(-1) data stream with a bit-error ratio below the threshold for hard-decision forward-error correction.This power consumption represents the lowest value demonstrated for a non-resonant Mach–Zehnder modulator in any material system.It is enabled by a novel class of organic electro-optic materials that are designed for high chromophore density and enhanced molecular orientation.The device features an electro-optic coefficient of r33<180 pm V^(-1) and can be operated at data rates of up to 40 Gbit s^(-1). | Sebastian Koeber Robert Palmer Matthias Lauermann Wolfgang Heni Delwin L Elder Dietmar Korn Markus Woessner Luca Alloatti Swen Koenig Philipp C Schindler Hui Yu Wim Bogaerts Larry R Dalton Wolfgang Freude Juerg Leuthold Christian Koos | 2015 | Light(Science & Applications)2015，4，1： | 4 |
| 5 | P6 aeupoint injec- tion reduce postoperative nausea and vomiting显示文摘 | Shyr M H Hsu J C Wu Y W Hui Y L Tan P P | 1990 | Ma Tsui Hsueh Tsa Chi Anaesthesiol Sinica1990，28，6： | 1 |
| 6 | Forward-se- cure multisignature and blind signature schemes显示文摘 | Chow S S M Hui L C K Yiu S M | 2005 | Applied Mathematics and Computation2005，168，： | 1 |
| 7 | GLP-1 promotes islet cells growth and inhibits cell apoptosis in Zucker diabetic rats 显示文摘 | Farilla L hui H Bertolotto C | 2002 | Endocrinology2002，143，11： | 1 |
| 8 | A framework for a logistics E-commerce community network:The Hong Kong air cargo industry显示文摘 | Leung L C Cheung W Hui Y V | 2000 | IEEE Transactions on SMC2000，30，4： | 1 |
| 9 | Hydrogen-bonding interactions between water and the one- and two-electron-reduced forms of vitamin K1: Applying quinone electrochemistry to determine the moisture content of non-aqueous solvents显示文摘 | Hui Y Chng ELK Chng C Y L | 2009 | Journal of the American Chemical Society2009，31，4： | 1 |
| 10 | Cryptanalysis of Harn digital multisignature scheme with distinguished signing authorities显示文摘 | Li Z C Hui L C K Chow K P | 2000 | Electronics Letters2000，36，4： | 1 |
| 11 | Synthesis and characterization of surfactant- stabilized Pt/C nanocatalysts for fuel cellapplications显示文摘 | Prabhuram J Wang X C Hui L | 2003 | J Phys Chem B2003，107，11： | 1 |
| 12 | Glucagon -like -peptide - 1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats 显示文摘 | Farilla L Hui H Bertolotto C | 2002 | Endocrinology2002，143，： | 1 |
| 13 | Genotype C hepatitis B virus infection is associated with an increased risk of hepatocellular carcinoma显示文摘 | Chan H L Hui A Y Wong M L Tse A M Hung L C Wong V W | 2004 | Gut2004，53，： | 1 |
| 14 | Airfreight forwarder shipment planning: A mixed 0-1 model and managerial issues in the integration and consolidation of shipments 显示文摘 | Wong W H Leung L C Hui Y V | 2009 | European Journal of Operational Researeh2009，193，： | 1 |
| 15 | 显示文摘 | Prabhuram J Wang X Hui C L | 2003 | Journal Physi- cal Chemistry B2003，107，11： | 1 |
| 16 | Hepatitis B virus genotype C takes a more aggressive disease course than hepatitis B virus genotype B in hepatitis B e antigen-positive patients显示文摘 | Chan H L Wong M L Hui A Y Hung L C Chan F K Sung J J | 2003 | J Clin Microbiol2003，41，： | 1 |
| 17 | A 0-1 LP Model for the integration and consolidation of air cargo Shipments显示文摘 | Leung L C Hui Y V Wang Y | 2009 | Operation Research2009，57，2： | 1 |
| 18 | Antitumor effect and en hancement of cytotoxic drug activity by cetuximab in nasopha ryngeal carcinoma cells显示文摘 | Sung F L Poon T C Hui E P | 2005 | In Vivo2005，19，1： | 1 |
| 19 | Room-temperature slow light with semiconductor quantum-dot devices显示文摘 | HUI SU SHUN L C | 2006 | JOSA OPT LETT2006，31，2： | 1 |
| 20 | Forecasts and reliability analysis of port cargo throughput in Hong Kong显示文摘 | Lam William H K Pan L P Seabrooke W Hui E C M | 2004 | Journal of Urban Planning and Development2004，130，3： | 1 |
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