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| 1 | Acute respiratory distress syndrome and lung injury: Pathogenetic mechanism and therapeutic implication显示文摘To review possible mechanisms and therapeutics for acute lung injury(ALI) and acute respiratory distress syndrome(ARDS). ALI/ARDS causes high mortality. The risk factors include head injury, intracranial disorders, sepsis, infections and others. Investigations have indicated the detrimental role of nitric oxide(NO) through the inducible NO synthase(i NOS). The possible therapeutic regimen includes extracorporeal membrane oxygenation, prone position, fluid and hemodynamic management and permissive hypercapnic acidosis etc. Other pharmacological treatments are anti-inflammatory and/or antimicrobial agents, inhalation of NO, glucocorticoids, surfactant therapy and agents facilitating lung water resolution and ion transports. β-adrenergic agonists are able to accelerate lung fluid and ion removal and to stimulate surfactant secretion. In con-scious rats, regular exercise training alleviates the endotoxin-induced ALI. Propofol and N-acetylcysteine exert protective effect on the ALI induced by endotoxin. Insulin possesses anti-inflammatory effect. Pentobarbital is capable of reducing the endotoxin-induced ALI. In addition, nicotinamide or niacinamide abrogates the ALI caused by ischemia/reperfusion or endotoxemia. This review includes historical retrospective of ALI/ARDS, the neurogenic pulmonary edema due to head injury, the detrimental role of NO, the risk factors, and the possible pathogenetic mechanisms as well as therapeutic regimen for ALI/ARDS. | Chain-Fa Su Shang Jyh Kao Hsing I Chen | 2012 | World Journal of Critical Care Medicine2012，1，2： | 12 |
| 2 | Acute lung injury and acute respiratory distress syndrome: experimental and clinical investigations显示文摘尖锐的肺损害(所有) 或尖锐呼吸悲痛症候群(ARDS ) 能与各种各样的混乱被联系。最近的调查在各种各样的混乱引起的 ALI 或 ARDS 的病原的机制上与临床的调查者和病理学家合作包含了临床的研究。这文学评论包括一篇摘要历史 ALI/ARDS 回顾,神经原的肺的浮肿由于从我们的实验室的头损害,长期的试验性的研究和临床的调查,有害角色没有,风险因素,和象为 ALI/ARDS 的治疗学的政体一样的可能的病原的机制。 | Hsing I Chen | 2011 | Journal of Geriatric Cardiology2011，8，1： | 7 |
| 3 | Perihepatic nodes detected by point-of-care ultrasound in acute hepatitis and acute-on-chronic liver disease显示文摘AIM: To study the manifestations of perihepatic lymph nodes during the episode of acute hepatitis flare by point-of-care ultrasonography.METHODS: One hundred and seventy-six patients with an episode of acute hepatitis flare(ALT value > 5 × upper normal limit) were enrolled retrospectively. Diagnosis of etiology of the acute hepatitis flare was based on chart records and serological and virological assays. The patients were categorized into two groups(viral origin and non-viral origin) and further defined into ten subgroups according to the etiologies. An ultrasonograpy was performed within 2 h to 72 h(median, 8 h). The maximum size of each noticeable lymph node was measured. Correlation between clinical parameters and nodal manifestations was analyzed RESULTS: Enlarged lymph nodes(width ≥ 5mm)were noticeable in 110(62.5%) patients, mostly in acute on chronic hepatitis B(54.5%). The viral group had a higher prevalence rate(89/110 = 80.9%) and larger nodal size(median, 7 mm) than those of the non-viral group(21/66 = 31.8%; median, 0 mm)(P < 0.001 for both). Meanwhile, there were significant differences in the nodal size between acute and chronic viral groups(P < 0.01), and between acute hepatitis A and non-hepatitis A viral groups(P < 0.001). In logistical regression analysis, the nodal width still showed strong significance in multivariate analysis(P < 0.0001) to stratify the two groups. The area under the curve of ROC was 0.805, with a sensitivity of 80.9%, a specificity of 68.2%, positive predictive value of 80.92%, negative predictive value of 68.18%, and an accuracy of 76.14%. CONCLUSION: Point-of-care ultrasonography to detect perihepatic nodal change is valuable for clarifying the etiologies in an episode of acute hepatitis flare. | I Che Feng Szu Jen Wang Ming Jen Sheu Lok-Beng Koay Ching Yih Lin Chung Han Ho Chi Shu Sun Hsing Tao Kuo | 2015 | World Journal of Gastroenterology2015，21，44： | 2 |
| 4 | Characterizations of Eu,Dy co-doped SrAl2O4 phosphors prepared by the solid-state reaction with B2O3addition显示文摘 | Chang Y L Hsing I H Liang M T | 2008 | Journal of Alloys Compounds2008，461，： | 1 |
| 5 | Characterization of strontium aluminate phosphors prepared from milled SrCO3 显示文摘 | CHANG Yu-lun Hsiang Hsing I Liang Ming Tsai | 2009 | Ceramics International2009，35，3： | 1 |
| 6 | Preparation and characterization of hybrid Nafion-silica membrane doped with phosphotungstic acid for high temperature operation of proton exchange membrane fuel cells显示文摘 | Shao Z G Joghee P Hsing I M | 2004 | Journal of Membrane Science2004，229，1： | 1 |
| 7 | Composite Nafion/polyvinyl alcohol membranes for the direct methanol fuel cell 显示文摘 | Shao Z G Wang X Hsing I M | 2002 | Journal of Membrane Science2002，210，1： | 1 |
| 8 | Silane Functional Effects on the Rheology and Ab-rasion Resistance of Transparent SiO2/UV-CurableResin Nano-Composites显示文摘 | HSIANG Hsing I CHANG Yu Lun CHEN Chi Yu etal | 2010 | Materials Chemistry andPhysics2010，120，23： | 1 |
| 9 | A new photoanode architecture of dye sensitized solar cell based on ZnO nanotetrapods with no need for calcination显示文摘 | W Chen H F Zhang I M Hsing | 2009 | Electrochem Commun2009，11，： | 1 |
| 10 | Two-dimensional simulation of water transport in polymer electrolyte fuel cells显示文摘 | HSING I M FUTERKO P | 2000 | Chem Eng Sci2000，55，19： | 1 |
| 11 | Effects of particle size of BaTiO3 powder on the dielectric properties of BaTiO3/PVDF composites显示文摘 | Hsing H I Lin K Yen F Hwang C | 2001 | Journal of Material Science2001，36，： | 1 |
| 12 | An improved TMAH Si-etching solution without attacking exposed aluminum显示文摘 | GUIZHEN Y CHAN P C H HSING I M | 2001 | Sensors & Actuators A2001，89，12： | 1 |
| 13 | 显示文摘 | Wang Xin Hsing I M | 2002 | Electrochimica Acta2002，472，： | 1 |
| 14 | Two-dimensional fi- nite-element method study of the resistance of mem- branes in polymer electrolyte fuel cells 显示文摘 | HSING I M FUTERKO P | 2000 | Elec- trochimica Acta2000，45，： | 1 |
| 15 | Real time electrochemical monitoring of PCR amplicons using electroactive hydrolysis probe显示文摘 | Luo F X Xuan F Hsing I M | 2011 | Electrochemistry Communications2011，13，7： | 1 |
| 16 | Immobilization-free multiplex electrochemical DNA and SNP detection显示文摘 | Luo X Hsing I M | 2009 | Biosens Bioelectron2009，25，4： | 1 |
| 17 | Risk factors for intrahepatic and extrahepatic cholangiocarcinoma in the United States: a population-based case-control study显示文摘 | Welzel T M Graubard B I El-Serag H B Shaib Y H Hsing A W Davila J A | 2007 | Clin Gastroenterol Hepatol2007，5，： | 1 |
| 18 | The embryo proper flowering directly form ginseng callus显示文摘 | CHANG W C HSING Y I | 1980 | Nature1980，284，： | 1 |
| 19 | Well-dispersed multiwalled carbon nanotubes supported platinum nanocatalysts for oxygen reduction显示文摘 | LI X GE S HUI C L HSING I M | 2004 | Electrochem Solid State Lett2004，7，9： | 1 |
| 20 | Surfactant stabilized Pt and Pt alloy electrocatalyst for polymer electrolyte fuel cells 显示文摘 | WANG X HSING I M | 2002 | Electrochim Acta2002，47，18： | 1 |
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