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19篇 您的检索式：作者名="HOYAS S"

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		题名	作者	年代	出处	被引量
	1	Numerical Modelling of Cavitation : Validation and Parametric Studies 显示文摘	MARGOT X HOYAS S GIL A	2012	Engineering Applications of Computational Fluid Mechanics2012，6，1：	1
	2	Simulation of forest fire fronts using cellular automata显示文摘	HERNANDEZ ENCINAS A HERNANDEZ ENCINAS L HOYA WHITE S	2007	Adv in Eng Software2007，38，6：	1
	3	Thermocapillary and thermogravitatory waves in a convection problem 显示文摘	HOYAS S HERRERO H MANCHO A M	2004	Theoretical and Computational Fluid Dynamics2004，18，5：	1
	4	Modeling epidemics using cellular automata 显示文摘	Hoya White S Martin del Rey A Rodrlguez Sanchez G	2007	Applied Mathematics and Computation2007，186，：	1
	5	Reynolds number effects on the Reynolds-stress budgets in turbulent channels显示文摘	Hoyas S Jiménez J	2008	Physics of Fluids2008，20，10：	1
	6	Simulation of forest fire fronts using cellular automata 显示文摘	Hernamdez Encinas A Hern6ndez Encinas L Hoya White S	2007	Advances in Engineering Software2007，38，6：	1
	7	Heat trans fer analysis of intermittent grinding processes 显示文摘	Perez J Hoyas S Skuratov D L	2008	International Journal of Heat and Mass Transfer2008，51，1516：	1
	8	The CHEK2 1100delC allele is not relevant for risk assessment in HNPCC and HBCC Spanish families显示文摘	Ana Sánchez de Abajo Miguel de la Hoya Javier Godino Vicente Furió Alicia Tosar Pedro Pérez-Segura Eduardo Díaz-Rubio Trinidad Caldés	2005	Familial Cancer2005，，2：	1
	9	Simulation of forest fire fronts using cellular automata显示文摘	Hernandez Encinas A Hernandez Encinas L Hoya White S	2007	Ad- vances in Engineering Software2007，38，6：	1
	10	Simulation of forest fire fronts using cellular automata 显示文摘	HERNANDEZ E A HERNANDEZ E L HOYA W S	2007	Advances in Engineering Software2007，38，：	1
	11	Molecular analysis of colorectal cancer tumors from patients with mismatch repair proficient hereditary nonpolyposis colorectal cancer suggests novel carcinogenic pathways显示文摘	Sánchez-de-Abajo A de la Hoya M van PM	2007	Clin Cancer Res2007，13，19：	1
	12	Genomic rearrangements at the BRCA1 locus in Spanish families with breast/ovarian cancer显示文摘	de la Hoya M Gutiérrez-Enríquez S Velasco E	2006	Clin Chem2006，52，8：	1
	13	Modelling forest fire spread using hexagonal cellular automata显示文摘	L. Hernández Encinas S. Hoya White A. Martín del Rey G. Rodríguez Sánchez	2006	Applied Mathematical Modelling2006，，6：	1
	14	Reynolds Number Effects on the Reynolds-Stress Budgets in Turbulence Channels显示文摘	Hoyas S JimenezJ	2008	Physics of Fluids2008，20，10：	1
	15	Numerical simulation and extended validation of two-phase com- pressible flow in diesel injector nozzles显示文摘	Salvador F J Hoyas S Novella R	2010	Journal of Automobile Engineering2010，225，：	1
	16	Numerical Simu- lation and Extended Validation of Two-Phase Compress- ible Flow in Diesel Injector Nozzles 显示文摘	Salvador F J Hoyas S Novella R	2011	Proceedings of the Institution of Mechanical Engineers Part D: Journal of Automobile Engineering2011，225，4：	1
	17	Scaling of the velocity fluctuations in turbulent channels up to Retau=2003显示文摘	Hoyas S Jiménez J	2006	Physics of Fluids2006，18，011702：	1
	18	Numerical Modelling of Cavitation: Validation and Parametric Studies 显示文摘	MARGOT X HOYAS S GIL A	2012	Engineering Ap- plications of Computational Fluid Mechanics2012，6，1：	1
	19	Low prevalence of germline hMSH6 mutations in colorectal cancer families from Spain显示文摘AIM: To investigate the prevalence and penetrance of hMSH6 mutations in Spanish HNPCC families that was negative for mutation in hMLH1 or hMSH2.METHODS: We used PCR-based DGGE assay and direct Sequencing to screen for hMSH6 gene in 91 HNPCC families.RESULTS: we have identified 10 families with germ-line mutations in the DNA sequence. These mutations included two intronic variation, three missense mutation, one nonsense mutation, and four silent mutations. Among the 10 germ-line mutations identified in the Spanish cohort,8 were novel, perhaps, suggesting different mutational spectra in the Spanish population. Detailed pedigrees were constructed for the three families with a possible pathogenic hMSH6 mutation. The two silent mutations H388H and L758L, detected in a person affected of colorectal cancer at age 29, produce loss of the wild-type allele in the tumor sample. Immunohistochemical analysis showed that expression of MSH6 protein was lost only in the tumors from the carriers of V878A and Q263X mutations.CONCLUSION: Altogether, our results indicate that disease-causing germ-line mutations of hMSH6 are very less frequent in Spanish HNPCC families.	Ana Sánchez de Abajo Miguel de la Hoya Alicia Tosar Javier Godino Juan Manuel Fernández Jose Lopez Asenjo Beatriz Perez Villamil Pedro Perez Segura Eduardo Diaz-Rubio Trinidad Caldes	2005	World Journal of Gastroenterology2005，11，37：	1

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