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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | 冠状动脉内影像学临床应用专家共识(第一部分):对冠状动脉介入治疗的指导与优化显示文摘欧洲心血管介入协会(EAPCI)专家组系统总结了血管内超声(IVUS)和光学相干断层成像(OCT)这两种血管内影像学检查临床应用指征的现有证据,提供了关于IVUS和OCT指导经皮冠状动脉介入治疗(PCI)的应用价值,并明确了最可能从腔内影像学指导的介入治疗中获得临床收益的患者或病变类型,同时详细论述了PCI前如何使用IVUS或OCT优化支架尺寸(支架长度和直径)和手术策略的选择。此外,专家推荐对支架失败(支架内再狭窄或支架内血栓形成)的患者应常规进行冠状动脉内影像学检查,并首选OCT。最后,重点论述了IVUS和OCT在指导PCI和评估支架失败两个方面的优势和局限性,并对未来需要深入研究的领域进行了展望。 | Lorenz Raber Gary S Mintz Konstantinos C Koskinas Thomas W Johnson Niels R Holm Yoshinubo Onuma Maria D Radu Michael Joner Bo Yu Haibo Jia Nicolas Meneveau Jose M.de la Torre Hemandez Javier Escaned Jonathan Hill Francesco Prati Antonio Colombo Carlo di Mario Evelyn Regar Davide Capodanno William Wijns Robert A Byme Giulio Guagliumi | 2019 | 中华心血管病杂志2019，47，1： | 17 |
| 3 | 心房颤动——当今面临的挑战显示文摘在过去数年里,临床和科撞方面对心房颤动(房颤)的关注明显增加,有关这一论题的出版物数量迅速、稳定的增长就是证明。虽然已有一些新方法治疗遮一心律失常一但大多数房颤患者仍然不得不忍受这一心律失常,包括其不良后果和症状,房颤无疑是虽迫切需要有更好治疗方法的一种心律失常。为了达到这一目的,就需要更深刻地认识房颤的机制.以便开发直接影响这一基础病理生理机制的治疗措施。 | Olsson SB Hansson A Hedin E Holm M Ingemansson M Johansson R Meurling C Pehrson S Roijer A Yuan S 方丕华 | 1997 | 中华心律失常学杂志1997，1，1： | 3 |
| 4 | Cognitive and adaptive outcome in low-grade pediatric cerebellar astrocytomas: evidence of diminished cognitive and adaptive functioning in National Collaborative Research Studies (CCG 9891/POG 9130).显示文摘 | Beebe DW Ris MD Armstrong FD Fontanesi J Mulhern R Holmes E Wisoff JH | 2005 | 中国神经肿瘤杂志2005，3，3： | 3 |
| 5 | Electroluminescence in conjugated polymers 显示文摘 | FRIEND R H GYMER R W HOLMES A B | 1999 | Nature1999，397，： | 2 |
| 6 | Role of β-microseminoprotein from prostate cancer initiationto recurrence: A mini-review显示文摘Medline/Pubmed articles relevant to this topic were considered using the search terms ?-microseminoprotein, MSMB, prostate secretory protein of 94 amino acids and PSP94. Full articles were retrieved when the abstract was considered relevant. In addition, other data related to this topic including our own are discussed. Summary of fi ndings-?-microseminoprotein(MSMB) is increasingly being considered as a marker for prostatecancer, as reduced levels have been associated with the disease. Here we review various aspects of this protein including its biological and physiological variants, binding proteins and immune modulation; its importance as a marker for biochemical recurrence of prostate cancer; prostate cancer related splice variants and its therapeutic utility. Two of the most important properties of MSMB are related to anticancer functions and immune modulation. Predominant expression of two(short and full-length) splice variants of MSMB has been observed from normal prostate and several other tissues. In benign prostate hyperplasia the short isoform is dominant, constituting 98% of this isoform, whereas in prostate cancer 96% constitute the fulllength isoform. The MSMB promoter single nucleotide polymorphism rs10993994 with the C allele functions as an activated cyclic adenosine monophosphate response element binding protein binding site. This C variant of rs10993994 could be responsible for the production of splice variants under variable conditions. MSMB has binding motifs to a few known proteins including immunoglobulin G and several Cysteine-rich secretory proteins family proteins. MSMB bound to these proteins is considered as immune modulating. Use of MSMB as a urinary marker for detecting aggressive prostate cancers that could resist radiation and surgical treatments, seems possible, but needs further investigation. The ratio of MSMB splice variants could also be a possible approach in understanding prostate cancers, with higher ratios indicating severe disease. | Nishi Karunasinghe Karen Bishop Pamela Murray Yuanye Xu Megan Goudie Lance Ng Shuotun Zhu Dug Yeo Han Lynnette R Ferguson Jonathan Masters Benji Benjamin Michael Holmes | 2014 | World Journal of Clinical Urology2014，3，1： | 2 |
| 7 | Al2O3对赤铁矿烧结过程的影响显示文摘主要分析了Al2O3对烧结过程“初熔”相物理化学特性的影响,阐述了含有不同形态Al2O3,的高铝铁矿石对烧结矿结构、烧结矿质量以及烧结过程的影响,探讨了Al2O3,对烧结矿低温还原粉化性能(RDI)的影响机理,提出了3种解决高铝铁矿石烧结的方法(中和法、稀释法、富集法),并简述了优化烧结原料以及烧结过程的可行措施。 | L Lu R J Holmes J R Manuel 张代华(译) 周茂军(校) | 2007 | 世界钢铁2007，7，5： | 2 |
| 8 | Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial显示文摘 | Friedrich W Mohr Marie-Claude Morice A Pieter Kappetein Ted E Feldman Elisabeth St?hle Antonio Colombo Michael J Mack David R Holmes Marie-angèle Morel Nic Van Dyck Vicki M Houle Keith D Dawkins Patrick W Serruys | 2013 | The Lancet . 2013 (9867)2013，，9867： | 2 |
| 9 | Therapy effect of either paelitaxel or eyelophosphamide eombination treatment in patients with epithelial ovarian cancer and relation to TP53 gene status 显示文摘 | Smith-Sorensen B Kaem J Holm R | 1998 | Br J Cancer1998，78，3： | 1 |
| 10 | Nutrition know-how: Combating pressure sores nutritionally显示文摘 | Holmes R | 1987 | Am J Nurs1987，87，10： | 1 |
| 11 | 显示文摘 | Holm R Storp S | 1976 | Journal of Electron Spectroscopy and Related Phenomena1976，8，2： | 1 |
| 12 | Comparison of to tal oral bioavailability and the lymphatic transport of halofantrine from three different unsaturated triglycerides in lymph-cannulated conscious rats 显示文摘 | Holm R Mtillertz A Christensen E | 2001 | Eur J Pharm Sci2001，14，4： | 1 |
| 13 | APOBEC-mediated viral restriction: not simply editing? 显示文摘 | Holmes R K Malim M H Bishop K N | 2007 | Trends Biochem Sci2007，32，3： | 1 |
| 14 | The social readjustment rating scale显示文摘 | Holmes T H Rahe R h | 1967 | Psy- chosomatic Medicine1967，11，2： | 1 |
| 15 | Hyppothalamic arousel,insulin resistance and Type 2 dibetes millitus显示文摘 | Bjorntorp P Holm G Rosmond R | 1999 | Diabe Med1999，16，5： | 1 |
| 16 | In vitro replication of mouse hepatitis virus strain A59显示文摘 | Compton J R Rogers D B Holmes K V | 1987 | J Virol1987，61，： | 1 |
| 17 | ChitosanN-sulfate,A watersoluble polyelectrolyte 显示文摘 | Holme K R Perlin A | 1997 | Carbohydrate Research1997，302，： | 1 |
| 18 | Reconstruction of images of deep space objects using Fourier Telescopy显示文摘 | HOLMES R B BRINKLEY T | 1999 | SPIE1999，3815，： | 1 |
| 19 | Compensatory growth in the rainbow trout, Saimo gairdneri Richardson 显示文摘 | Dobson S H Holmes R M | 1984 | J Fish Biol1984，25，： | 1 |
| 20 | p53, p21 and mdm2 expression vs the response to radiotherapy in transitional cell carcinoma of the bladder显示文摘 | Rotterud R Berner A Holm R | 2001 | BJU Int2001，88，3： | 1 |
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