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| 1 | Treatment of corticosteroid-resistant ulcerative colitis with oral low molecular weight heparin显示文摘 | Cui HF Jiang XL | 1999 | World Journal of Gastroenterology1999，5，5： | 24 |
| 2 | Progress in Numerical Simulation of Solidification Process of Shaped Casting显示文摘Solidification simulation of manufacturing shaped casting which plays an important role in asSuring the soundness and quality of castings, in minimizing the trial production time and in reducing the manufacturing cost becomes one of the hottest topics of the new research frontiers of foundry technology at home and abroad. Practical three dimensional computer numerical simulation system for temperature distribution during solidification as well as shrinkage cavity and porosity prediction has already been put into application all over the world. Further fundamental researche5 on fluid flow, thermal stress and micro-modeling as well as practical approaches of numerical simulation of solidification process of shaped castings for routine analysis of foundry industry are still underway. | LIU, BC SHEN, HF LI, WZ | 1995 | Journal of Materials Science & Technology1995，11，5： | 18 |
| 3 | Ion Channels in Mesenchymal Stem Cells from Rat Bone Marrow显示文摘 | Li GR Deng XL Sun H Chung SS Tse HF Lau CP | 2006 | 中国生物学文摘2006，20，5： | 18 |
| 4 | An Sm-Nd isotopic dating study of the Archean Kongling Complex in the Huangling area of the Yangtze Craton显示文摘Sm Nd isotopic compositions of associated amphibolites, TTG gneisses and granitic gneisses from the Archean Kongling Complex of the Yangtze Craton, South China are systematically analyzed. The results show that the amphibolites and TTG gneisses have a similar age of ca. 2 700 Ma, which well agrees with zircon U Pb dating of previous studies. However, their ε Nd ( t ) are different, suggestive of possible dissimilarity in source composition. | Ling, WL Gao, S Zheng, HF Zhou, L Zhao, ZB | 1998 | Chinese Science Bulletin1998，43，14： | 13 |
| 5 | Transcription-coupled nucleotide excision repair in mammalian cells: molecular mechanisms and biological effects显示文摘有脱氧核糖核酸损害的 RNA II (RNAPIIo ) 有的伸长的相遇为这个事件为 P53 依赖的 apoptosis 提供一个强壮的信号的房间和房间的严重后果骑车拘捕。为了抵抗,延长了抄写的阻塞,房间由联合抄写的修理(TC-NER ) 移开堵住 RNAPIIo 脱氧核糖核酸损害,核苷酸切除修理(NER ) 的一条专业化潜水艇小径。到 UVB 光或化学药品的老鼠的暴露阐明了那 TC-NER 是免于 genotoxic 暴露的尖锐有毒、长期的效果(癌症) 的一条批评幸存小径。在 TC-NER 的缺乏在产生稀罕人的混乱安乐乡症候群(CS ) 的 CSA 和 CSB 基因与变化被联系。最近的数据建议 CSA 和 CSB 在哺乳动物的 TC-NER 起微分作用:是的 CSB 联合因素吸引 NER 蛋白质,染色质 remodellers 和对阻止的 RNAPIIo 复杂的 CSA- E3-ubiquitin 连接酶的一个修理。CSA 为 NER 蛋白质的吸引力是非必需的,还在有 CSB 的合作被要求到成员 XAB2, nucleosomal 绑定蛋白质 HMGN1 和 TFIIS。TC-NER 的新兴的图画是复杂的:没有脱氧核糖核酸拖延损坏的 RNAPIIo 的排水量,堵住抄写的损害的修理发生,并且要求至少二个必要集会因素(CSA 和 CSB ) ,核心 NER 因素(除了 XPC-RAD23B ) ,并且 TC-NER 特定的因素。这些和还未辩别出的蛋白质将完成堵住抄写的损害的有效修理不仅,但是也是可能的贡献脱氧核糖核酸损坏发信号事件。 | Mafia Fousteri Leon HF Mullenders | 2008 | Cell Research2008，18，1： | 10 |
| 6 | Thiazolidinedione increases serum soluble receptor for advanced glycation end-products in type 2 diabetes显示文摘 | Tan, KCB Chow, WS Tso, AWK Xu, A Tse, HF Hoo, RLC Betteridge, DJ Lam, KSL | 2007 | 中国生物学文摘2007，21，11： | 7 |
| 7 | Bioactive asterosaponins from the starfish Culcita novaeguineae显示文摘 | Tang HF Yi YH Li L Sun P Zhang SQ Zhao YP | 2005 | 第二军医大学学报2005，26，8： | 5 |
| 8 | Purging of murine erythroblastic leukemia by ZnPcS2P2-based-photodynamic therapy显示文摘 | Huang HF Chen YZ Wu Y Chen P | 2006 | 中国生物学文摘2006，20，5： | 5 |
| 9 | 2014年中国钛工业发展报告显示文摘从产能、产量、市场、价格、对外贸易等方面对中国海绵钛、钛锭、钛粉、钛加工材等主要相关钛产品的生产及销售情况进行了统计,并在此基础上对2014年中国钛工业的总体运营状况进行了评价,对取得的技术进步进行了回顾。分析了目前我国钛行业存在的突出问题,并给出了相应的对策及建议:1以创新驱动为抓手,推动企业转型升级;2加大科技创新力度,促进高性能钛合金加工材产品升级;3加强行业间的合作,搭建信息、资源的共享平台,拓宽钛的应用市场。 | China Nonferrous Metal Industry Association Ti,Zr,Hf Branch | 2015 | 钛工业进展2015，32，2： | 5 |
| 10 | The four-and-a-half-LIM protein 2 (FHL2) is overexpressed in gliomas and associated with oncogenic activities显示文摘Glia. 2008 Jul 9.Four-and-a-half-LIM protein 2 (FHL2) is a member of FHL protein family, which plays a crucial role in regulating geneexpression, cell survival, and migration.Although its function in oncogenesis appears to be tumor type-specific, its roles | Ng SS Yew DT Wong BC Kung HF | 2008 | 中国神经肿瘤杂志2008，6，2： | 3 |
| 11 | Interaction of Nicotine and Bovine Serum Albumin显示文摘 | Wang, Y Cheng, Y Sun, HF | 2000 | Chinese Chemical Letters2000，11，3： | 3 |
| 12 | Experimental study of gold distribution in the algae-organic matter-fluid system显示文摘THE previous simulating experiments show that many algae can greatly accumulate goldfrom solution under some conditions. Some other experiments further indicate that organ-ic matter and crude oil can also play an important role in gold geochemistry processes such asleaching, migration, reduction and precipitation. However, these biometallogeneses are | Xie, SC Yin, HF Wang, HM Zhou, XG Fu, JM Sheng, GY Zhang, HZ Lu, JL | 1997 | Chinese Science Bulletin1997，42，19： | 3 |
| 13 | Mitochondrial neuronal uncoupling proteins:a target for potential disease-modification in Parkinson’s disease Philip显示文摘This review gives a brief insight into the role of mitochondrial dysfunction and oxidative stress in the converging pathogenic processes involved in Parkinson’s disease(PD).Mitochondria provide cellular energy in the form of ATP via oxidative phosphorylation,but as an integral part of this process,superoxides and other reactive oxygen species are also produced.Excessive free radical production contributes to oxidative stress.Cells have evolved to handle such stress via various endogenous anti-oxidant proteins.One such family of proteins is the mitochondrial uncoupling proteins(UCPs),which are anion carriers located in the mitochondrial inner membrane.There are five known homologues(UCP1 to 5),of which UCP4 and 5 are predominantly expressed in neural cells.In a series of previous publications,we have shown how these neuronal UCPs respond to 1-methyl-4-phenylpyridinium(MPP+;toxic metabolite of MPTP)and dopamine-induced toxicity to alleviate neuronal cell death by preserving ATP levels and mitochondrial membrane potential,and reducing oxidative stress.We also showed how their expression can be influenced by nuclear factor kappa-B(NF-B)signaling pathway specifically in UCP4.Furthermore,we previously reported an interesting link between PD and metabolic processes through the protective effects of leptin(hormone produced by adipocytes)acting via UCP2 against MPP+-induced toxicity.There is increasing evidence that these endogenous neuronal UCPs can play a vital role to protect neurons against various pathogenic stresses including those associated with PD.Their expression,which can be induced,may well be a potential therapeutic target for various drugs to alleviate the harmful effects of pathogenic processes in PD and hence modify the progression of this disease. | WL Ho Jessica WM Ho Hui-Fang Liu Danny HF So Zero HM Tse Koon-Ho Chan David B Ramsden Shu-Leong Ho | 2012 | Translational Neurodegeneration2012，1，1： | 3 |
| 14 | Discovery and significance of Xucun late Proterozoic composite dike swarm in southern Anhui Province显示文摘GEOLOGICALLY, southern Anhui Province, East China, is a part of late Proterozoic collision orogens of the southeast margin of the Yangtze Block. In this region the development of late Proterozoic Fuchuan ophiolite suite and collision granitoids of Xiuning, Xucun and Shexian mark the existence of the intensely tectonic-magmatic events. Recently discovered Xucun | Tang, HF Zhou, XM Zhi, LG | 1997 | Chinese Science Bulletin1997，42，4： | 2 |
| 15 | Measurement of electrical conductivity of 0.001 mol NaCl solution under high pressures显示文摘The experiments were carried out in a YJ-3000 ton press fitted with a wedge-type cubic anvil. The samples were pressed using pyropgyllite as the pressure medium. The conductance cell for the experiments was made of Teflon and platinum metal was used as electrodes. The detailed method for setting up of sample has been reported. | Zheng, HF Xie, HS Xu, YS Song, MS Guo, J Zhang, YM | 1997 | Chinese Science Bulletin1997，42，18： | 2 |
| 16 | Phenotypes of the COX-deficient mice indicate physiological and pathophysiological roles for COX-1 and COX-2显示文摘 | Loftin CD Tiano HF Langenbach R | 2002 | Prostag Lip Mediat2002，6869，： | 2 |
| 17 | Removing polybrominated diphenyl ethers in pure water using Fe/Pd bimetallic nanoparticles显示文摘Polybrominated diphenyl 醚(PBDE ) 广泛地被用作 fire-retardants。由于他们的高生产体积,普遍用法,和环境坚持, PBDE 在各种各样的 environments.Nanoscale zero-valent 铁(ZVI ) 成为了无所不在的沾染物是为许多 halogenated 有机化合物的有效 reductant。提高降级效率, ZVI/Palladium 二金属的 nanoparticles (nZVI/Pd ) 在这研究被综合降级水里的 decabromodiphenyl 醚(BDE209 ) 。约 90% BDE209 被 nZVI/Pd 很快在 80 min 以内移开,而大约 25% BDE209 被 nZVI 移开。由 nZVI/Pd 的 BDE209 的降级适合伪 first-order 动力学。pH 的增加严厉地导致了减少 BDE209 的率降级。在有在 9.0 点的起始的 pH 的处理的降级率常数是超过 6.8 ? ?? 猠数瑣潲桰瑯浯瑥祲 ????????? 焠慵瑮晩捩瑡潩吗?? | Min ZHANG Jian LU ZhenchengXU Yiliang HF Bo ZHANG Song JIN Brian BOMAN | 2015 | Frontiers of Environmental Science & Engineering2015，9，5： | 2 |
| 18 | Histopathological changes in the oesophageal mucosa in Egyptian children with corrosive strictures: A single-centre vast experience显示文摘BACKGROUND The caustic ingestion continues to be a major problem worldwide especially in developing countries. The long-term complications include stricture and increased life time risk of oesophageal carcinoma. Patients suffered from corrosive induced oesophageal strictures have more than a 1000-fold risk of developing carcinoma of the oesophagus.AIM To determine the possibility of oesophageal mucosal dysplasia after prolonged dilatation in post corrosive stricture.METHODS This observational study was conducted at the Paediatric Endoscopy Unit in Cairo University Children's Hospital. It included children of both sexes older than 2 years of age who had an established diagnosis of post-corrosive oesophageal stricture and repeated endoscopic dilatation sessions for more than 6 mo. All patients were biopsied at the stricture site after 6 mo of endoscopic dilatation. A histopathological examination of an oesophageal mucosal biopsy was performed for the detection of chronic oesophagitis, inflammatory cellular infiltration and dysplasia.RESULTS The mean age of the enrolled children was 5.9 ± 2.6 years; 90% of the patients had ingested an alkaline corrosive substance(potash). The total number of endoscopic dilatation sessions were ranging from 16 to 100 with mean number of sessionswas 37.2 ± 14.9. Histopathological examination of the specimens showed that 85%of patients had evidence of chronic oesophagitis(group A) in the form of basal cell hyperplasia, hyperkeratosis and subepithelial fibrosis. Thirteen percent of the patients had evidence of reactive atypia(group B) in the form of severe neutrophilic intraepithelial inflammatory cellular infiltration, and 2 patients(2%)had mild squamous dysplasia(group C); we rebiopsied these two patients 6 mo after the initial pathological assessment, guided by chromoendoscopy by Lugol's iodine.CONCLUSION The histopathology of oesophageal mucosal biopsies in post-corrosive patients demonstrates evidence of chronic oesophagitis, intraepithelial inflammatory cellular infiltration and dysplasia. Dysplasia is one of the complications of postcorrosive oesophageal stricture. | Ayman EskANDer Carolyne Ghobrial Nabil A Mohsen Bahaa Mounir Dalia Abd EL-Kareem Sara Tarek Mortada HF El-Shabrawi | 2019 | World Journal of Gastroenterology2019，25，7： | 2 |
| 19 | 持续血糖监测用于检测危重症患儿高血糖的前瞻性研完显示文摘目的用组织间隙持续血糖监测仪评价PICU非糖尿病患儿血糖增高程度,并与实验室间断检测血糖的方法比较,评价监测效果。设计前瞻性、观察性研究。场所西马萨诸塞州一所医学中心拥有10张床位的PICU。对象20名非糖尿病患儿,年龄1~18岁,预计需要2d以上的重症监护。干预在患儿皮下放置持续血糖监测仪,征得患儿及家属同意后,另接探头进行72h连续血糖监测并与实验室所测血糖水平进行比较。测量指标和主要结果平均每位患儿持续监测685.2h,共有16337次探头读数,43.0%读数高于125mg/dl(6.9mmol/L),27.2%高于140mg/dl(7.8mmol/L),4%高于200mg/dl(11.1mmol/L)。实验室血糖值提示升高的频度不如持续监测,且易错过血糖升高的关键时段。结论PICU患儿可出现显著血糖升高,实验室间断检测血糖可能低估此现象。 | Allen HF Rake A Roy M | 2008 | 中国小儿急救医学2008，15，2： | 2 |
| 20 | Molecular and immunological detection of circulating rumor cells and micrometastases from solid tumor显示文摘 | Pelkey TJ Frierson -HF Bruns DE | 1996 | Clinical Chemistry1996，42，9： | 2 |
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