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	题名	作者	年代	出处	被引量
1	Selective serotonin re-uptake inhibitor sertraline inhibits bone healing in a calvarial defect model显示文摘Bone wound healing is a highly dynamic and precisely controlled process through which damaged bone undergoes repair and complete regeneration. External factors can alter this process, leading to delayed or failed bone wound healing. The findings of recent studies suggest that the use of selective serotonin reuptake inhibitors(SSRIs) can reduce bone mass, precipitate osteoporotic fractures and increase the rate of dental implant failure. With 10% of Americans prescribed antidepressants, the potential of SSRIs to impair bone healing may adversely affect millions of patients' ability to heal after sustaining trauma. Here, we investigate the effect of the SSRI sertraline on bone healing through pre-treatment with(10 mg·kg^(-1) sertraline in drinking water, n = 26) or without(control, n = 30) SSRI followed by the creation of a 5-mm calvarial defect. Animals were randomized into three surgical groups:(a) empty/sham,(b) implanted with a DermaMatrix scaffold soak-loaded with sterile PBS or(c) DermaMatrix soak-loaded with542.5 ng BMP2. SSRI exposure continued until sacrifice in the exposed groups at 4 weeks after surgery. Sertraline exposure resulted in decreased bone healing with significant decreases in trabecular thickness, trabecular number and osteoclast dysfunction while significantly increasing mature collagen fiber formation. These findings indicate that sertraline exposure can impair bone wound healing through disruption of bone repair and regeneration while promoting or defaulting to scar formation within the defect site.	R.Nicole Howie Samuel Herberg Emily Durham Zachary Grey Grace Bennfors Mohammed Elsalanty Amanda C.LaRue William D.Hill James J.Cray	2018	International Journal of Oral Science2018，10，4：	5
2	Mutilcolour fluorescent detection and mapping of AFLP makers in chicken ( Gallus domesticus)显示文摘	Herbergs J M Siwek A P M A Crooijmans J J	1999	Animal Genetics1999，30，：	1
3	Analysis of A-kinase anchoring protein (AKAP) interaction with protein kinase A (PKA) regulatory subunits: PKA isoform specificity in AKAP binding 显示文摘	Herberg FW Maleszka A Eide T	2000	J Mol Biol2000，298，2：	1
4	Efficacy, tolerability and patient benefit of ultrasound-assisted wound treatment versus surgical debridement: a randomized clinical study 显示文摘	Herberger K Franzke N Blome C	2011	Dermatology2011，222，3：	1
5	Rapid palatal expansion followed by fixed appliances:a long-term evaluation of changes in arch dimension显示文摘	McNamara JA Baccetti T Fianchi L Herberger TA		0，，04：	1
6	A longi- tudinal study of skeletal side effects induced by rapid maxillary expansion显示文摘	Chang JY McNamara JA Jr Herberger TA	1997	Am J Orthod Dentofacial Orthop1997，112，3：	1
7	A longitudinal study of skeletal side effects induced by rapid maxillary expansion显示文摘	Chang JY Mcnamara JA Herberger TA	1997	Am J Orthod Dentofacial Orthop1997，112，3：	1
8	Economic implications ofan early postoperative enteral feeding显示文摘	Herberg AM Laiwson DR Adag La	1999	J Amdiet Assoc1999，99，7：	1
9	The adipokine leptin increases skeletal muscle mass and significantly alters skeletal muscle miRNA expression profile in aged mice显示文摘	Hamrick MW Herberg S Arounleut P		0，，3：	1
10	Multicolout fluorescent detection and mapping of AFLP markies in chicken(Gallus somesticus)显示文摘	Herbergs J	1999	Animal Genetics1999，30，：	1
11	Perfectly-secure key distribution for dynamic conferences显示文摘	BLUNDO C De SANTIS A HERBERG A	1998	Information and Computation1998，146，1：	1
12	Myringotomy and ventilation tuheinsertion: a ten-year follow-up显示文摘	Riley DN Herberger S McBride G	1997	J Laryngol Otol1997，111，：	1
13	Stromal Cell-Derived factor1 B mediates cell survival through enhancing autophagy in bone MarrowDerived mesenchymal stem cells显示文摘	Herberg S Shi X Johnson MH	2013	PLo S One2013，8，58：	1
14	Stromal cell-derived factor-1βmediates cell survival through enhancing autophagy in bone marrow-derived mesenchymal stem cells显示文摘	Herberg S Shi X Johnson MH	2013	Plo S One2013，8，58：	1
15	Carbon dioxide extraction of residual solvents in poly(lactide-co-glycolide)microparticles显示文摘	Herberger J Murphy K Munyakazi L	2003	J Controlled Release2003，90，2：	1
16	Excretion and tissue distribution of[14C]monensin in cattle显示文摘	Herberg R Manthey J Richardson L		0，，：	1
17	Remote ischemic pereonditioning is effective alone and in combination with intravenous tissue-type plasminogen activator in routine model of embolic stroke 显示文摘	Hoda MN Siddiqui S Herberg S	2012	Stroke2012，43，10：	1
18	An adipogenic serum factor in genetically obese rodents显示文摘	LOFFLER G FEICK G HAUNER H HERBERG L	1983	FEBS Lett1983，153，：	1
19	Detec- tion of human effluents by a MOS gas sensor in correla- tion to VOC quantification by GC/MS显示文摘	HERBERGER S HEROLD M ULMER H	2010	Building and Environment2010，45，11：	1
20	Stromal Cell Derived factor-1β mediates cell survival through enhancing autophagy in bone Marrow-Derived mesenchymal stem cells显示文摘	Herberg S Shi X Johnson MH	2013	PLoS One2013，8，58：	1

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