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| 1 | 羧甲基木薯淀粉的取代方式研究显示文摘采用高效液相色谱(HPLC)和核磁共振波谱(1HNMR)分析了混水/有机介质中合成羧甲基木薯淀 粉的取代方式。发现HPLC是一种测定不同条件下合成的羧甲基木薯淀粉取代度(DS)的可靠方法。在测量 的范围内,未取代、一取代、二取代和三取代无水葡萄糖单元的摩尔分数分布和Spurlin模型非常吻合。用高 分辨率500MHz1HNMR分析了木薯淀粉羧甲基过程的取代度和反应顺序。依据淀粉和羧甲基淀粉(CMS) 的结构确定了各个峰位置。比较所得数据发现:依据HPLC计算的DSHPLC小于从500MHz1HNMR计算所得 的DS。无水葡萄糖单元中C2、C3和C6的羧甲基化反应顺序为C6>C2>C3。 | 姚杰 尤宏 包正 沈晋 Klaassien J Ganzeveld Jan Henk Marsman Hero J Heeres 陈文仁 | 2005 | 分析化学2005，33，2： | 8 |
| 2 | Using induced pluripotent stem cells as a tool for modelling carcinogenesis显示文摘Cancer is a highly heterogeneous group of diseases that despite improved treatments remain prevalent accounting for over 14 million new cases and 8.2 million deaths per year. Studies into the process of carcinogenesis are limited by lack of appropriate models for the development and pathogenesis of the disease based on human tissues. Primary culture of patient samples can help but is difficult to grow for a number of tissues. A potential opportunity to overcome these barriers is based on the landmark study by Yamanaka which demonstrated the ability of four factors;Oct4, Sox2, Klf4, and c-Myc to reprogram human somatic cells in to pluripotency. These cells were termed induced pluripotent stem cells(i PSCs) and display characteristic properties of embryonic stem cells. This technique has a wide range of potential uses including disease modelling, drug testing and transplantation studies. Interestingly i PSCs also share a number of characteristics with cancer cells including self-renewal and proliferation, expression of stem cell markers and altered metabolism. Recently, i PSCs have been generated from a number of human cancer cell lines and primary tumour samples from a range of cancers in an attempt to recapitulate the development of cancer and interrogate the underlying mechanisms involved. This review will outline the similarities between the reprogramming process and carcinogenesis, and how these similarities have been exploited to generate i PSC models for a number of cancers. | Emma L Curry Mohammad Moad Craig N Robson Rakesh Heer | 2015 | World Journal of Stem Cells2015，7，2： | 5 |
| 3 | Measurement of muscle activity with magnetic resonance elastography显示文摘 | Guido Heers Thomas Jenkyn M. Alex Dresner Marc-Oliver Klein Jeffrey R Basford Kenton R Kaufman Richard L Ehman Kai-Nan An | 2003 | Clinical Biomechanics2003，，6： | 2 |
| 4 | Genetic associations in diabetic nephropathy: a meta-analysis显示文摘 | A. L. Mooyaart E. J. J. Valk L. A. Es J. A. Bruijn E. Heer B. I. Freedman O. M. Dekkers H. J. Baelde | 2011 | Diabetologia2011，，3： | 2 |
| 5 | Eco-industrial park initiatives in the USA and the Netherlands: first lessons显示文摘 | R.R. Heeres W.J.V. Vermeulen F.B. de Walle | 2004 | Journal of Cleaner Production2004，，8： | 2 |
| 6 | Measuring physical and mechanical properties of individual carbon nanotubes by in situTEM显示文摘 | Wang Z L Poncharal P de Heer W A | 2000 | J Phys Chem Solids2000，61，7： | 2 |
| 7 | 显示文摘 | De Heer W A Chatelain A Ugarte D | 1995 | Science1995，270，： | 2 |
| 8 | From space to earth: advances in human physiology from 20 years of bed rest studies (1986-2006) 显示文摘 | Traon APL Heer M Narici MV | 2007 | European Journal of Applied Physiology2007，101，2： | 1 |
| 9 | Zinc hydroxystannate as an alternative synergist to antimony trioxide in polyester resins containing halogenated flame retardants 显示文摘 | Cusack P A Heer M S Monk A W | 1997 | Polymer Degradation and Stability1997，58，2： | 1 |
| 10 | A carbon nanotube field emission electron source显示文摘 | De Heer W A Chatelain A Ugarte D | 1995 | Science1995，270，： | 1 |
| 11 | Carbon nanotubes-the route toward application 显示文摘 | Baughman R H Zakhidoy A A Heer W A | 2003 | Science2003，297，： | 1 |
| 12 | A carbon nanotube field-emission electron source显示文摘 | de Heer W A Chaotelain A Ugarte D | 1995 | Science1995，270，： | 1 |
| 13 | Cerebral vas- culitis associated with gemcitabine 显示文摘 | Schmorl P Heer - Sonderhoff A Vosshenrich R | 2010 | Urologe A2010，49，2： | 1 |
| 14 | Aberrant ex- pression of extracellular signal regulated kinase 5 in human pros-tate cancer显示文摘 | Mccracken SR Ramsay A Heer R | 2008 | Oncogene2008，27，21： | 1 |
| 15 | Zinc hydroxystannate as an al- ternative synergist to antimony trioxide in polyester resins contain- ing halogenated flame retardants 显示文摘 | Cusack P A Heer M S Monk A W | 1997 | Polymer Degradation and Sta- bility1997，58，12： | 1 |
| 16 | Electron field emitters based on carbon nanotube films显示文摘 | De Heer W A Bonard J M Fauth K | 1997 | Adv Mater1997，9，： | 1 |
| 17 | Preoperative serum vascular endothelial growth factor can predict stage in colorectal cancer显示文摘 | Kumer H Heer K Lee PW | 1998 | Clin Cancer Res1998，4，5： | 1 |
| 18 | Synthesis and Screening of a New Group of Fungicides 1-(2-Phenyl-1,3-dioxolan-2-ylmethyl)-1,2,4-triazoles显示文摘 | VAN G J HEERS J JANSSEN M | 1980 | Pestic Sci1980，11，1： | 1 |
| 19 | The syntax definition formalism SDF-reference manual显示文摘 | HEERING J HENDRIKS P R H | 1989 | ACM SIGPLAN Notice1989，24，11： | 1 |
| 20 | Measuring physical and mechanical properties of individual carbon nanotubes by in situ TEM显示文摘 | Wang Z L Poncharal P De Heer W A | 2000 | Phys Chem Solids2000，61，7： | 1 |
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