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| 1 | Compared efficacy of preservation solutions on the outcome of liver transplantation:Meta-analysis显示文摘AIM To compare the effects of the four most commonly used preservation solutions on the outcome of liver transplantations.METHODS A systematic literature search was performed using MEDLINE, Scopus, EMBASE and the Cochrane Library databases up to January 31^(st), 2017. The inclusion criteria were comparative, randomized controlled trials(RCTs) for deceased donor liver(DDL) allografts with adult and pediatric donors using the gold standard University of Wisconsin(UW) solution or histidinetryptophan-ketoglutarate(HTK), Celsior(CS) and Institut Georges Lopez(IGL-1) solutions. Fifteen RCTs(1830 livers) were included; the primary outcomes were primary non-function(PNF) and one-year posttransplant graft survival(OGS-1). RESULTS All trials were homogenous with respect to donor and recipient characteristics. There was no statistical difference in the incidence of PNF with the use of UW, HTK, CS and IGL-1(RR = 0.02, 95%CI: 0.01-0.03, P = 0.356). Comparing OGS-1 also failed to reveal any difference between UW, HTK, CS and IGL-1(RR = 0.80, 95%CI: 0.80-0.80, P = 0.369). Two trials demonstrated higher PNF levels for UW in comparison with the HTK group, and individual studies described higher rates of biliary complications where HTK and CS were used compared to the UW and IGL-1 solutions. However, the meta-analysis of the data did not prove a statistically significant difference: the UW, CS, HTK and IGL-1 solutions were associated with nearly equivalent outcomes.CONCLUSION Alternative solutions for UW yield the same degree of safety and effectiveness for the preservation of DDLs, but further well-designed clinical trials are warranted. | Agnes Lilla Szilágyi Péter Mátrai Péter Hegyi Eszter Tuboly Daniella Pécz András Garami Margit Solymár Erika Pétervári Márta Balaskó Gábor Veres László Czopf Bastian Wobbe Dorottya Szabó Juliane Wagner Petra Hartmann | 2018 | World Journal of Gastroenterology2018，24，16： | 5 |
| 2 | A comparative investigation of DNA adducts, DNA strand breaks and gene mutations induced by benzopyrene and (+/-)-anti-benzopyrene-7,8-diol 9,10-oxide in cultured human cells显示文摘 | Hanelt S Helbig R Hartmann A | 1997 | Mutat Res1997，390，12： | 2 |
| 3 | Caspase-3:A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease显示文摘 | Hartmann A Hunot S Michel PP | 2000 | PNAS2000，27，： | 1 |
| 4 | Intermittent saline flushes during haemodialysis do not alleviate coagulation and clot formation in stable patients receivingreduced doses of dalteparin显示文摘 | Sagedal S Hartmann A Osnes K | 2006 | Nephrol Dial Transplant2006，21，2： | 1 |
| 5 | Expression of vascular endothelial growth factor and pigment epithelial-derived factor in a rat model of retinopathy of prematurity显示文摘 | Hartmann JS Thompson H Wang H Kanekar S Huang W Budd S J | 2011 | Mol Vis2011，17，： | 1 |
| 6 | The inflammatory response in the Parkinson brain显示文摘 | Hunot S Hartmann A Hirsch EC | | 0，，： | 1 |
| 7 | Relation between lipoprotein(a) and fibrinogen and serial intravascular ultrasound plaque progression in left main coronary arteries 显示文摘 | Hartmann M von Birgelen C Mintz G S | 2006 | JAm Coil Cardiol2006，48，3： | 1 |
| 8 | Caspase-3:A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson’s disease显示文摘 | Hartmann A Hunot S Michel PP | 2000 | Proc Natl Acad Sci U S A2000，97，6： | 1 |
| 9 | Digital current controller for a 1 MHz, 10 kW three-phase VIENNA rectifier显示文摘 | Hartmann M Round S Erfl H | 2009 | IEEE Transactions on Industrial Electronics2009，24，11： | 1 |
| 10 | Experimental investigation of heuristics for resource-constrained project scheduling: an update显示文摘 | KOLISCH R HARTMANN S | 2006 | European Journal of Operational Research2006，174，1： | 1 |
| 11 | Intraocular availability of topically applied mycophenolate mofetil in rabbits 显示文摘 | Knapp S Bertelmann E Hartmann C | 2003 | J Ocul Pharmcol Ther2003，19，2： | 1 |
| 12 | Extensive ribosomal DNA genic variation in the columnar cactus Lophocereus显示文摘 | Hartmann S Nason JD Bhattacharya D 2001 | 2001 | J Mol Evol2001，53，： | 1 |
| 13 | High frequency of p53 gene mutations in primary breast cancers in Japanese women;a low-incidece population显示文摘 | Hartmann A Blallszyk H Saitoh S | 1996 | Br J Cancer1996，73，8： | 1 |
| 14 | 显示文摘 | Wachtlin J Schrunder S Pham D T Hoffmann F Hartmann C | 1998 | Ophthalmologe1998，95，： | 1 |
| 15 | Gastroin-testinal nematode infection interferes with experimentalallergic airway inflammation but not atopic dermatitis显示文摘 | Hartmann S Schnoeller C Dahten A | 2009 | Clin Exp Allergy2009，39，15： | 1 |
| 16 | Umbilical cord tissue- derived mesenchymal stem cells grow best under GMP-eom- pliant culture conditions and maintain their phenotypic and fun- ctional properties 显示文摘 | Hartmann I Hollweck T Haffner S et ol | 2010 | J Immunol Methods2010，363，1： | 1 |
| 17 | Using climate forecasts for water management:Arizona and the 1997-1998 El Ni(n)o显示文摘 | Pagano T C Hartmann H C Sorooshian S | | 0，，5： | 1 |
| 18 | Molecular cloning of SVP: a negative regulator of the floral transition in Ar- abidopsis显示文摘 | Hartmann U Hohmann S Nettesheim K et a l | 2000 | The Plant Journal2000，21，4： | 1 |
| 19 | Z-path SAW RFID tag显示文摘 | Harma S Plessky V P Hartmann C S | 2008 | IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control2008，55，1： | 1 |
| 20 | A competitive genetic algorithm for the resource-constrained project scheduling显示文摘 | Hartmann S | 1998 | Naval Research Logistics1998，45，7： | 1 |
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