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| 1 | Transfer of Natural Micro Structures to Bionic Lightweight Design Proposals显示文摘 | M. Maier D. Siegel K.-D. Thoben N. Niebuhr C. Hamm | 2013 | Journal of Bionic Engineering2013,10,4: | 6 |
| 2 | Immune checkpoint therapy for pancreatic cancer显示文摘Novel treatment modalities are necessary for pancreatic cancer. Immunotherapy with immune checkpoint inhibition has shown effect in other solid tumors, and could have a place in pancreatic cancer treatment. Most available clinical studies on immune checkpoint inhibitors for pancreatic cancer are not yet completed and are still recruiting patients. Among the completed trials, there have been findings of a preliminary nature such as delayed disease progression and enhanced overall survival after treatment with immune checkpoint inhibitors in mono- or combination therapy. However, due to small sample sizes, major results are not yet identifiable. The present article provides a clinical overview of immune checkpoint inhibition in pancreatic cancer. Pub Med, Clinical Trials.gov and American Society of Clinical Oncology's meeting abstracts were systematically searched for relevant clinical studies. Four articles, five abstracts and 25 clinical trials were identified and analyzed in detail. | Henrik Johansson Roland Andersson Monika Bauden Sarah Hammes Stefan Holdenrieder Daniel Ansari | 2016 | World Journal of Gastroenterology2016,22,43: | 4 |
| 3 | Fibroadhesive scarring of grafted collagen scaffolds interferes with implant–host neural tissue integration and bridging in experimental spinal cord injury显示文摘Severe traumatic spinal cord injury(SCI)results in a devastating and permanent loss of function,and is currently an incurable condition.It is generally accepted that future intervention strategies will require combinational approaches,including bioengineered scaffolds,to support axon growth across tissue scarring and cystic cavitation.Previously,we demonstrated that implantation of a microporous type-I collagen scaffold into an experimental model of SCI was capable of supporting functional recovery in the absence of extensive implant–host neural tissue integration.Here,we demonstrate the reactive host cellular responses that may be detrimental to neural tissue integration after implantation of collagen scaffolds into unilateral resection injuries of the adult rat spinal cord.Immunohistochemistry demonstrated scattered fibroblast-like cell infiltration throughout the scaffolds as well as the presence of variable layers of densely packed cells,the fine processes of which extended along the graft–host interface.Few reactive astroglial or regenerating axonal profiles could be seen traversing this layer.Such encapsulation-type behaviour around bioengineered scaffolds impedes the integration of host neural tissues and reduces the intended bridging role of the implant.Characterization of the cellular and molecular mechanisms underpinning this behaviour will be pivotal in the future design of collagen-based bridging scaffolds intended for regenerative medicine. | Haktan Altinova Sebastian Hammes Moniek Palm Jose Gerardo-Nava Pascal Achenbach Ronald Deumens Emmanuel Hermans Tobias Fuhrmann Arne Boecker Sabien Geraldine Antonia van Neerven Ahmet Bozkurt Joachim Weis Gary Anthony Brook | 2019 | Regenerative Biomaterials2019,6,2: | 4 |
| 4 | New biochemical markers for myocardial cell injury显示文摘 | Hamm CW Katus HA | 1995 | Curr Opin Cardiol1995,10,4: | 2 |
| 5 | 在接受治疗的急性冠状动脉综合征患者中,肌钙蛋白峰值与长期缺血事件之间的关系显示文摘非ST段抬高急性冠状动脉综合征(acutecoro-narysyndromes,ACS)患者肌钙蛋白水平与结局的关系虽然已经明确,但接受抗血小板治疗管理的非ST段抬高ACS患者肌钙蛋白水平与长期结局的关系尚未明确。 | 刘莉 叶鹏 Goldstein SA Newby LK Cyr DD Neely M Lüscher TF Brown EB White HD Ohman EM Roe MT Hamm CW | 2017 | 中华高血压杂志2017,25,5: | 2 |
| 6 | New biochemical markers for myocardial cell injury 显示文摘 | Hamm CW Katus HA | 1995 | Current Opinion Cardiol1995,10,: | 2 |
| 7 | Role of B-type natriuretic peptide (BNP) and NT- proBNP in clinical routine 显示文摘 | Weber M Hamm C | 2006 | Heart2006,92,6: | 1 |
| 8 | Overexpression of sarcolemmal calcium pump attenuates induction of cardiac gene expression in response to ET-1 显示文摘 | Piuhola J Hammes A Schuh K | 2001 | Am J Physiol Regul Integr Comp Physiol2001,281,3: | 1 |
| 9 | Characterization of Lactobacillus coryniformis DSM 20001T surface protein mediating coaggregation with and aggregation among pathogens 显示文摘 | Schachtsiek M Hammes WP Hertel C | 2004 | Applied and Environmental Microbiology2004,70,12: | 1 |
| 10 | Effect of ecological factors on the inhibitory spectrum and activity of bacteriocins 显示文摘 | Ganzle M G Weber S Hammes W P | 1999 | Intemational Journal of Food Microbiology1999,48,: | 1 |
| 11 | Epidermal growth factor receptor signaling is required for normal ovarian steroidogenesis and oocyte maturation显示文摘 | Jamnongjit M Gill A Hammes S R | 2005 | Proc Natl Acad Sci U S A2005,102,16: | 1 |
| 12 | Frequent expression loss ofInter-alpha-trypsin inhibitor heavy chain (ITIH) genes in multi- pie human solid tumors: a systematic expression analysis显示文摘 | Hamm A Veeck J Bektas N | 2008 | BMC Cancer2008,8,: | 1 |
| 13 | Dynamic contrast-enhanced magnetic resonance imaging and pharmacokinetic models in prostate cancer 显示文摘 | Franiel T Hamm B Hricak H | 2011 | Eur Radiol2011,21,: | 1 |
| 14 | Insulin resistance and risk of chronic kidney disease in nondiabetic US adults显示文摘 | Jing Chen Paul Muntner Lee Hamm | 2003 | J Am Soc Nephrol2003,14,3: | 1 |
| 15 | Soluble CD40 ligand in Acute Coronary Syndromes显示文摘 | Heeschen G Dimmeler S Hamm CW | 2003 | N Engl J Med2003,348,12: | 1 |
| 16 | Effect of food components and processing parameters on DNA degradation in food 显示文摘 | Bauer T Hammes W P Haase N U | 2004 | Environ Biosafety Res2004,3,: | 1 |
| 17 | Metal de- contamination of soil, sediment, and sewage sludge by means of transitionmetal chelant -EDDS 显示文摘 | Vandevivere P Hammes F Verstraete W | 2001 | Jour- nal of Environmental Engineering2001,127,9: | 1 |
| 18 | Variabil- ity of shore and shoreline evolution显示文摘 | STIVE M J F AARNINKHOF S G J HAMM L | 2002 | Coastal Engineering2002,47,2: | 1 |
| 19 | Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy显示文摘 | Hammes HP Du X Edelstein D | 2003 | Nat Med2003,9,: | 1 |
| 20 | Statistics-based outlier detection for wireless sensor networks显示文摘 | Zhang Y Hamm N Meratnia N | 2012 | International Journal of Geographical InformationScience2012,26,8: | 1 |