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| 1 | Disaster preparedness, pediatric considerations in primary blast injury, chemical, and biological terrorism显示文摘Both domestic and foreign terror incidents are an unfortunate outgrowth of our modern times from the Oklahoma City bombings, Sarin gas attacks in Japan, the Madrid train bombing, anthrax spores in the mail, to the World Trade Center on September 11 th, 2001. The modalities used to perpetrate these terrorist acts range from conventional weapons to high explosives, chemical weapons, and biological weapons all of which have been used in the recent past. While these weapons platforms can cause significant injury requiring critical care the mechanism of injury, pathophysiology and treatment of these injuries are unfamiliar to many critical care providers. Additionally the pediatric population is particularly vulnerable to these types of attacks. In the event of a mass casualty incident both adult and pediatric critical care practitioners will likely be called upon to care for children and adults alike. We will review the presentation, pathophysiology, and treatment of victims of blast injury, chemical weapons, and biological weapons. The focus will be on those injuries not commonly encountered in critical care practice, primary blast injuries, category A pathogens likely to be used in terrorist incidents, and chemical weapons including nerve agents, vesicants, pulmonary agents, cyanide, and riot control agents with special attention paid to pediatric specific considerations. | Mitchell Hamele William Bradley Poss Jill Sweney | 2014 | World Journal of Critical Care Medicine2014，3，1： | 14 |
| 2 | 一种基于数据挖掘的GIS及在航海中的应用显示文摘根据聚类分析方法中密度凝聚的思想 ,提出一种新的复合聚类分析算法 ,进一步将这种算法用于地理信息系统的数据挖掘 ,并应用于船舶航线的自动设计。 | 王天真 郝瑞吉 汤天浩 Ben■t MOMEUX Lionel HAMEL Guillaume EUDELINE | 2003 | 中国航海2003，26，3： | 5 |
| 3 | 法国青少年足球教学训练课的组织过程和教学模式显示文摘探析法国青少年足球教学训练课的过程和教学模式,为我国校园足球的科学化教学训练提供思路。法国青少年足球教学训练课的结构主要分为热身、比赛、技术练习、情景、比赛,课的教学环节通常分为准备工作、课的内容介绍、课的组织实施、纠正和总结等环节。法国青少年足球教学训练课中采用的教学模式主要有自主适应性教学模式、战术决策教学模式、执行性教学模式。 | 周志雄 Michel Hamel 吴宏 | 2016 | 体育教学2016，0，12： | 4 |
| 4 | 战略意图显示文摘十六年前,还是伦敦商学院一名讲师的加里·哈梅尔,与密歇根大学的教授普拉哈拉德合写了这篇文章。从此,两位重量级的管理大师走进了人们的视野。哈梅尔和普拉哈拉德认为,西方公司习惯于“削减”抱负以适应其资源,结果,它们只会寻求自己能够保持的优势。相比之下,日本的公司致力于加快组织学习的步伐,以最大限度地利用资源,并且力图达到看似不可能的目标。这些日本公司在员工中培养出一种对胜利的执著,并且通过宣扬全球性领导地位这一愿景,让这份执著持盈不减。这就是佳能“打败施乐”,小松“包围卡特彼勒”的方法。战略意图常常包含张力目标,迫使公司独辟蹊径进行竞争。在这篇获得“麦肯锡奖”的文章中,哈梅尔和普拉哈拉德描述了日本企业采用的四种方法:建立优势梯次,寻找薄弱环节,改变竞争条件,通过合作竞争。 | 加里·哈梅尔(Gary Hamel) 普拉哈拉德C.K.Prahalad 詹正茂(译) | 2005 | 哈佛商业评论2005，，8： | 2 |
| 5 | Understanding, management and modelling of urban hydrology and its consequences for receiving waters: A state of the art显示文摘 | T.D. Fletcher H. Andrieu P. Hamel | 2012 | Advances in Water Resources2012，，： | 2 |
| 6 | Serelaxin increases the antifibrotic action of rosiglitazone in a model of hepatic fibrosis显示文摘AIM To determine the effect of combined serelaxin and rosiglitazone treatment on established hepatic fibrosis.METHODS Hepatic fibrosis was induced in mice by carbon tetrachloride administration for 6 wk, or vehicle alone(nonfibrotic mice). For the final 2 wk, mice were treated with rosiglitazone, serelaxin, or both rosiglitazone and serelaxin. Serum liver enzymes and relaxin levels were determined by standard methods. The degree of liver collagen content was determined by histology and immunohistochemistry. Expression of type?Ⅰ?collagen was determined by quantitative PCR. Activation of hepatic stellate cells was assessed by alpha-smoothmuscle actin(SMA) levels. Liver peroxisome proliferator activated receptor-gamma coactivator 1 alpha(PGC1α) was determined by Western blotting.RESULTS Treatment of mice with CCl4 resulted in hepatic fibrosis as evidenced by increased liver enzyme levels(ALT and AST), and increased liver collagen and SMA. Monotherapy with either serelaxin or rosiglitazone for 2 wk was generally without effect. In contrast, the combination of serelaxin and rosiglitazone resulted in significantly improved ALT levels(P < 0.05). Total liver collagen content as determined by Sirius red staining revealed that only combination treatment was effective in reducing total liver collagen(P < 0.05). These results were supported by immunohistochemistry for type?Ⅰ?collagen, in which only combination treatment reduced fibrillar collagen levels(P < 0.05). The level of hepatic stellate cell activation was modestly, but significantly, reduced by serelaxin treatment alone, but combination treatment resulted in significantly lower SMA levels. Finally, while hepatic fibrosis reduced liver PGC1α levels, the combination of serelaxin and rosiglitazone resulted in restoration of PGC1α protein levels.CONCLUSION The combination of serelaxin and rosiglitazone treatment for 2 wk was effective in significantly reducing established hepatic fibrosis, providing a potential new treatment strategy. | Robert G Bennett Ronda L Simpson Frederick G Hamel | 2017 | World Journal of Gastroenterology2017，23，22： | 2 |
| 7 | Soil microbial quality associated with yield reduction in continuous-pea显示文摘 | Atul Nayyar Chantal Hamel Guy Lafond Bruce D. Gossen Keith Hanson Jim Germida | 2009 | Applied Soil Ecology2009，，1： | 2 |
| 8 | 管理学的“登月计划”显示文摘毫无疑问,管理是人类最重要的发明之一。一百多年来,管理领域不断取得进步,创建了各种结构、流程和方法,将人类活动凝聚在一起,进而推动了世界经济的持续发展。但是,大多数重大的管理突破都发生在数十年前。工作流程设计、年度预算编制、投资回报分析、项目管理、事业部制、品牌管理等不可或缺的管理工具,都是在20世纪初问世的。事实上,“现代”管理学的奠基人丹尼尔·麦卡勒姆(DanielMc Callum)、弗雷德里克·泰勒(Frederick Taylor)、亨利·福特(Henry Ford)等,都诞生于1865年美国内战结束之前,这多少有些讽刺的意味。 | 加里·哈梅尔(Gary Hamel) 郑娟(翻译) | 2009 | 商业评论2009，，7： | 2 |
| 9 | Quantitative Importance, Composition, and Seasonal Dynamics of Protozoan Communities in Polyhaline versus Freshwater Intertidal Sediments显示文摘 | I. Hamels K. Sabbe K. Muylaert W. Vyverman | 2004 | Microbial Ecology2004，，1： | 2 |
| 10 | Considerations for successful transplantation of encapsulated pancreatic islets显示文摘 | P. de Vos A. F. Hamel K. Tatarkiewicz | 2002 | Diabetologia2002，，2： | 2 |
| 11 | The core competence of the corporation 显示文摘 | PRAHALAD C K HAMEL G | 1990 | Harvard Business Review1990，68，3： | 1 |
| 12 | The core competence of the corporation 显示文摘 | Prahalad C K Hamel G | 1990 | Harvard Business Review1990，68，3： | 1 |
| 13 | The Why,What and How of Management Innovation显示文摘 | HAMEL G | 2006 | Harvard Business Review2006，84，2： | 1 |
| 14 | Soil microbial dynamics in maize growing soil under different tillage and residue management systems显示文摘 | Spedding T A Hamel C Mehuys G R | 2004 | Soil Biology and Biochemistry2004，，36： | 1 |
| 15 | The core competence of the cerpomtion显示文摘 | Prahalad C K Hamel G | 1990 | Harvard Business Review1990，，3： | 1 |
| 16 | Microbial fuel cells: methodology and technology显示文摘 | Logan B E Hamelers B Rozendal R | 2006 | Environmental Science Technology2006，40，17： | 1 |
| 17 | Collaborate with your customers and win显示文摘 | Hamel G Doz Y L Prahalad C K | 1989 | Harvard Business Review1989，，61： | 1 |
| 18 | Evaluation of the differ- ence in accuracy between implant placement by virtual planning data and surgical guide templates versus the conventional free-hand method-a combined in vivo-in vitro technique using cone-beam CT (Part Ⅱ ) 显示文摘 | Nickenig H J Wichmann M Hamel J | 2010 | J Craniomaxillofac Surg2010，38，7： | 1 |
| 19 | Synthesis of 2,2-dinitropropanol显示文摘 | Hamel E E Dehn J S Love J A | 1962 | Ind Eng Chem Prod Res Dev1962，1，2： | 1 |
| 20 | The core competence of the corporations 显示文摘 | Prahalad C K hamel G | 1990 | Harvard Business Review1990，，： | 1 |
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