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| 1 | Redox regulation in tumor cell epithelial-mesenchymal transition:molecular basis and therapeutic strategy显示文摘Epithelial–mesenchymal transition(EMT)is recognized as a driving force of cancer cell metastasis and drug resistance,two leading causes of cancer recurrence and cancer-related death.It is,therefore,logical in cancer therapy to target the EMT switch to prevent such cancer metastasis and recurrence.Previous reports have indicated that growth factors(such as epidermal growth factor and fibroblast growth factor)and cytokines(such as the transforming growth factor beta(TGF-β)family)are major stimulators of EMT.However,the mechanisms underlying EMT initiation and progression remain unclear.Recently,emerging evidence has suggested that reactive oxygen species(ROS),important cellular secondary messengers involved in diverse biological events in cancer cells,play essential roles in the EMT process in cancer cells by regulating extracellular matrix(ECM)remodeling,cytoskeleton remodeling,cell–cell junctions,and cell mobility.Thus,targeting EMT by manipulating the intracellular redox status may hold promise for cancer therapy.Herein,we will address recent advances in redox biology involved in the EMT process in cancer cells,which will contribute to the development of novel therapeutic strategies by targeting redox-regulated EMT for cancer treatment. | Jingwen Jiang Kui Wang Yan Chen Haining Chen Edouard C Nice Canhua Huang | 2017 | Signal Transduction and Targeted Therapy2017，2，1： | 5 |
| 2 | A theoretical and diagnostic study of somitary waves and atmopheric blocking显示文摘 | Butchart N Hains K Marshall J C | 1989 | J Atmos Sci1989，46，1314： | 2 |
| 3 | Transvaginal sonography and theconservative management of spontaneous abortion 显示文摘 | Haines C J Chung T Leung DY | 1994 | Gyneeol Obstet Invest1994，37，1： | 1 |
| 4 | Human infective endocarditis caused by Streptococcus suis serotype 2显示文摘 | Mohamed W Hain T | 2005 | J Clin Microbiol2005，43，9： | 1 |
| 5 | Can nitrogen budgets explain differences in soil nitrogen mineralization rates of forest stands along an elevation gradient 显示文摘 | BONITO G M COLEMAN D C HAINES B L | 2003 | Forest Ecology and Management2003，176，： | 1 |
| 6 | A function retained by the common mutant CLN3 protein is responsible for the late onset of juvenile neuronal ceroid lipofuscinosis 显示文摘 | Kitzmuller C Haines RL Codlin S | 2008 | Hum Mol Genet2008，17，2： | 1 |
| 7 | GPU accelerated radio astronomy signal convolution 显示文摘 | Harris C Haines K Staveley-Smith L | 2008 | Experimental Astronomy2008，22，12： | 1 |
| 8 | Attitudes toward euthanasia and physician-assisted sulcide: a study of the multivariate effects of healthcare training, patient characteristics, religion and locus of control 显示文摘 | Hains C A Hulbert-Williams N J | 2013 | J MedEthics2013，39，71： | 1 |
| 9 | Coping and problem solving of self-mutilators显示文摘 | Williams C L | 1997 | J Clin Psychol1997，53，2： | 1 |
| 10 | Lung cancer:diagnosis and management显示文摘 | Collins LG Haines C Perkel R | 2007 | Am Faro Physician2007，75，1： | 1 |
| 11 | Chronic active hepatitis in mice caused by Helicobacter hepaticus 显示文摘 | Ward J M Anver M R Haines D C | 1994 | Am J Pathol1994，145，4： | 1 |
| 12 | Can nitrogen budgets explain differences in soil nitrogen mineralization rates of forest stands along an elevation gradient? 显示文摘 | BONITO G M COLEMAN D C HAINES B L | 2003 | Forest Ecology and Management2003，176，： | 1 |
| 13 | Effects of low-intensity exercise conditioning on blood pressure,heart rate,and autonomic modulation of heart rate in men and women with hypertension显示文摘 | Hua L Brown C Hains S | 2009 | Biol Res Nurs2009，11，2： | 1 |
| 14 | A mathematical model for top-shelf vertigo: the role of sedimenting otoconia in BPPV显示文摘 | SQUIRE T M WEIDMAN M S HAIN T C | 2004 | J Biomech2004，37，： | 1 |
| 15 | The effects of exercise conditioning in normal and overweight pregnant women on blood pressure and heart rate variability 显示文摘 | STUTZMAN S S BROWN C A HAINS S M | 2010 | Biological Research for Nursing2010，12，2： | 1 |
| 16 | Association of porcine circovirus 2 with reproductive failure in pigs: a retrospective study,1995 - 1998 显示文摘 | Bogdan J West K Clark E Konoby C Haines D Allan G McNeilly F Meehan B Krakowka S Ellis JA | 2001 | Can Vet J2001，42，7： | 1 |
| 17 | A field guide to the insects and mites infesting cured fish显示文摘 | Haines C P Rees D P | 1998 | FAO Fisheries Technical Paper1998，，： | 1 |
| 18 | Clinical im- pliacations of a mathematical model of benign paroxys- mal position vertigo显示文摘 | HAIN T C SQUIRE T M STONE H A | 2005 | Ann N Y Acad Sci2005，1039，： | 1 |
| 19 | Can nitrogen budgets explain differences in soil nitrogen mineralization rates of forest stands along an elevation gradient显示文摘 | Coleman D C Haines B L | 2003 | Forest Ecology and Management2003，176，： | 1 |
| 20 | Silver and gold glyconano-particles for colorimetric bioassays显示文摘 | Schofield C L Haines A H Field R A Russell D A | 2006 | Langmuir2006，22，： | 1 |
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