4篇
您的检索式：作者名="Guo Xiaocan"
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| 1 | A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis显示文摘 | Shuying Shen Xiaocan Guo Huan Yan Yi Lu Xinyan Ji Li Li Tingbo Liang Dawang Zhou Xin-Hua Feng Jonathan C Zhao Jindan Yu Xing-Guo Gong Lei Zhang Bin Zhao | 2015 | Cell Research2015，25，9： | 10 |
| 2 | Comparing the diurnal variations in the SuperMAG auroral electrojet indices SML and SMU显示文摘Diurnal variations of the SuperMAG auroral electrojet indices(SML and SMU)were examined for the period of 1980–2010,and the differences between SML and SMU were especially analyzed.The diurnal variation of SML with a maximum at around 1100 UT has a prenoonpostnoon asymmetry.At solstices,the diurnal variation of SML is much stronger than that at equinoxes.For the SMU,two maxima are recorded in the diurnal variation with the bigger one at 1700 UT and the smaller one at 0400 UT.The seasonal variations are not obvious in the UT variation characteristics of SMU although the intensity of SMU is changed remarkably season by season.For both SML and SMU,the contributing stations are located at higher geomagnetic latitude around 1600 UT and at lower geomagnetic latitude around 0400 UT.These results indicate that:(1)the SML is mostly controlled by the convection electric field.Its diurnal variation is mainly correlated with the equinoctial and R-M hypothesis;(2)the SMU is largely controlled by the ionospheric conductance.Its diurnal variation is tightly correlated with the solar radiation. | Yuan Wang Aimin Du Gengxiong Chen Xin Cao Ying Zhang Min Li Xiaocan Liu Jianpeng Guo | 2014 | Chinese Science Bulletin2014，59，29： | 2 |
| 3 | Endogenous miRNA Sponge lincRNA-RoR Regulates Oct4, Nanog, and Sox2 in Human Embryonic Stem Cell Self-Renewal显示文摘 | Yue Wang Zhenyu Xu Junfeng Jiang Chen Xu Jiuhong Kang Lei Xiao Minjuan Wu Jun Xiong Xiaocan Guo Houqi Liu | 2013 | Developmental Cell2013，，1： | 1 |
| 4 | Computer-designed orthogonal RNA aptamers programmed to recognize Ebola virus glycoproteins显示文摘Ebola virus (EBOV), a member of the filovirus family, is an enveloped negative-sense RNA virus that causes lethal infections in humans and primates. Thousands of people have died from the Ebola virus disease (EVD) in West Africa, and no specific antiviral medication and treatment have been approved for EVD. Although the development of an EBOV vaccine is promising, immunity to any vaccine is not immediate. Here, we computationally analysed the structure of EBOV glycoprotein GP2 (GP2EBOV) and designed RNA aptamers that recognize and inhibit it. The aptamers specifically bind to conserved arginine residues (Arg587 and Arg596) located in the C-terminal coiled-coil region of GP2EBOV. Molecular docking of the synthetic RNA aptamers with the ectodomain of GP2EBOV revealed that the optimized orthogonal RNA aptamers have strong binding affinities with the coiled-coil region of GP2EBOV. The characterized RNA aptamers may facilitate strategies to block replication of EBOV and related Filoviruses, and thus may serve as important antivirals to reduce mortality associated with these infections. | Teng Yue Liu Shuxia Yang Shan Guo Xiaocan Zhang Yanwen Song Yajun Cui Yujun | 2019 | Biosafety and Health2019，1，2： | 0 |
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