|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 通过手术导致的重量损失由胃绕过在疾病的肥胖的病人改进非含酒精的脂肪肝疾病显示文摘 AIM:To evaluate the effects of surgical weight loss(Roux-en-Y gastric bypass with a modified Fobi-Capella technique) on non alcoholic fatty liver disease in obese patients.METHODS:A group of 26 morbidly obese patients aged 45 ± 2 years and with a body mass index > 40 kg/m 2 who underwent open surgical weight loss operations had paired liver biopsies,the first at surgery and the second after 16 ± 3 mo of weight loss.Biopsies were evaluated and compared in a blinded fashion.The presence of metabolic syndrome,anthropometric and biochemical variables were also assessed at baseline and at the time of the second biopsy.RESULTS:Percentage of excess weight loss was 72.1% ± 6.6%.There was a reduction in prevalence of metabolic syndrome from 57.7%(15 patients) to 7.7%(2 patients)(P < 0.001).Any significance difference was observed in aspartate aminotransferase or alanine aminotransferase between pre and postsurgery.There were improvements in steatosis(P < 0.001),lobular(P < 0.001) and portal(P < 0.05) inflammation and fibrosis(P < 0.001) at the second biopsy.There were 25(96.1%) patients with non alcoholic steatohepatitis(NASH) in their index biopsy and only four(15.3%) of the repeat biopsies fulfilled the criteria for NASH.The persistence of fibrosis(F > 1) was present in five patients at second biopsy.Steatosis and fibrosis at surgery were predictors of significant fibrosis postsurgery.CONCLUSION:Restrictive mildly malabsorptive surgery provides significant weight loss,resolution of metabolic syndrome and associated abnormal liver histological features in most obese patients. | Víctor Vargas Helena Allende Albert Lecube Maria Teresa Salcedo Juan A Baena-Fustegueras José M Fort Joaquín Rivero Roser Ferrer Roberto Catalán Eva Pardina Santiago Ramón y Cajal Jaime Guardia Julia Peinado-Onsurbe | 2012 | World Journal of Hepatology2012，4，12： | 6 |
| 2 | Cardiac alterations in cirrhosis: reversibility after liver transplantation显示文摘 | Mireia Torregrosa Santi Aguadé Laura Dos Rosa Segura Antonio Gónzalez Artur Evangelista Joan Castell Carlos Margarit Rafael Esteban Jaume Guardia Joan Genescà | 2004 | Journal of Hepatology2004，，1： | 3 |
| 3 | T cell responses and viral variability in blood donation candidates with occult hepatitis B infection显示文摘 | Marta Bes Victor Vargas Maria Piron Natalia Casamitjana Juan Ignacio Esteban Nuria Vilanova Asuncion Pinacho Josep Quer Lluis Puig Jaime Guardia Silvia Sauleda | 2011 | Journal of Hepatology2011，，4： | 2 |
| 4 | Citrus flavonoids: Molecular structure, biological activity and nutritional properties: A review显示文摘 | Elisa Tripoli Maurizio La Guardia Santo Giammanco Danila Di Majo Marco Giammanco | 2006 | Food Chemistry2006，，2： | 2 |
| 5 | Composting in a laboratory reactor: a review显示文摘 | Petiot C Guardia A D | 2004 | Composting Science & Utilization2004，12，1： | 1 |
| 6 | Spontaneous primary intra- ventrieular hemorrhage:clinical data, etiology and outcome显示文摘 | Marti-Fabregas J Piles S Guardia E et ai | 1999 | J Neu-rol1999，246，： | 1 |
| 7 | Application of machine-vision techniques to fish-quality assessment显示文摘 | Majid Dowlati Miguel de la Guardia | 2012 | Trends in Analytical Chemistry2012，，： | 1 |
| 8 | Correlation between serum magnesium levels and hepatic encephalopathy in imme- diate post liver transplantation period 显示文摘 | LOPES P J MEI MF GUARDIA AC | 2013 | Transplant Proc2013，45，3： | 1 |
| 9 | Role of roots and shoots in the regulation of the Fe efficiency responses in sunflower and cucumber显示文摘 | ROMERA F J ALCANTARA E DELA GUARDIA M D | 1992 | Plant Physiol1992，85，： | 1 |
| 10 | Vita- min C is an ideal substitute for hydrazine in the reduction of graphene oxide suspensions显示文摘 | Ferndndez-Merino M J Guardia L Paredes J I | 2010 | J Phys Chem C2010，114，： | 1 |
| 11 | Rapid detection of lamivudine-resistant hepatitis B virus polymerase gene variants显示文摘 | Jardi R Buti M Rodriguez FF Cotrina M Costa X Pascual C Esteban R Guardia J | | 0，，： | 1 |
| 12 | Flavanones in Citrus fruit:Structure-antioxidant activity relationships显示文摘 | Majo D D Giammanco M Guardia M L Tripoli E Giammanco S Finotti E | 2005 | Food Research International2005，38，： | 1 |
| 13 | Comparative study of flavonoids in experimental models of inflammation 显示文摘 | Rotelli AE Guardia T Juarez AO | 2003 | Pharmacol Res2003，48，6： | 1 |
| 14 | Prognostic value of pulsatility index in acute intracerebral hemorrhage 显示文摘 | Marti-Fabregas J Belvis R Guardia E | 2003 | Neurology2003，61，8： | 1 |
| 15 | New route to 15-hydroxydehydroabietic acid derivatives:application to the first synthesis of some bioactive abietane and nor-abietane type terpenoids显示文摘 | ALVAREZ E J CHAHBOUN R GUARDIA J J | 2006 | Tetrahedron Letters2006，47，15： | 1 |
| 16 | Headspace–mass spectrometry determination of benzene, toluene and the mixture of ethylbenzene and xylene isomers in soil samples using chemometrics显示文摘 | F.A. Esteve-Turrillas S. Armenta S. Garrigues A. Pastor M. de la Guardia | 2007 | Analytica Chimica Acta2007，，1： | 1 |
| 17 | Prognostic value of Pulsatility Index in acute intracerehral hemorrhage显示文摘 | Belvis R Guardia E | 2003 | Neurology2003，61，： | 1 |
| 18 | Hepatobiliary complications associated with total parenteral nutrition显示文摘 | Angelico M Della Guardia P | 2000 | Aliment Pharmacol Ther2000，14，2： | 1 |
| 19 | Detailed polybrominated diphenyl ether (PBDE) congener composition of the widely used pent,a-, octa-, and deea-PBDE technical flame-retardant mixtures 显示文摘 | Guardia M J Hale R C Hale R C | 2006 | Environmental Science and Technology2006，40，20： | 1 |
| 20 | Flavanones in citrus fruit: structure-antioxidant activity relationships显示文摘 | MAJO D D GIAMMANCO M GUARDIA M L | 2005 | Food Research International2005，38，10： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员