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| 1 | In-line X-ray phase-contrast imaging of murine liver microvasculature ex vivo显示文摘Imaging blood vessels is of importance for determining the vascular distribution of organs and tumors.Phase-contrast X-ray imaging can reveal the vessels in much more detail than conventional X-ray absorption method.Visualizing murine liver microvasculature ex vivo with phase-contrast X-ray imaging was performed at Shanghai Synchrotron Radiation Facility.Barium sulfate and physiological saline were used as contrast agents for the blood vessels.Blood vessels of <Φ20μm could be detected by replacing resident blood with physiological saline or barium sulfate.An entire branch of the portal vein (from the main axial portal vein to the ninth generation of branching) could be captured in a single phase-contrast image.It is demonstrated that selective angiography based on phase contrast X-ray imaging,with a physiological material of low Z elements (such as saline) being the contrast agent,is a viable imaging strategy.Further efforts will be focused on using the technique to image tumor angiogenesis. | LI Beilei XU Min WU Weizhong PENG Guanyun ZHANG Xi PENG Yifeng SHI Hongcheng CHEN Shaoliang | 2012 | Nuclear Science and Techniques2012，23，1： | 5 |
| 2 | Thermal and elemental analysis of the combustion chamber deposits in a large-scale two-stroke marine diesel engine显示文摘It is of significance to understand the chemical content of carbon deposits in the large-scale two-stroke(LSTS) marine diesel engine because of adverse effect on the engine performance, oil consumption and emissions. In this work, two different combustion chamber deposits in an LSTS marine diesel engine were studied using thermogravimetry analysis(TGA), elemental analysis(EA) and synchrotron X-ray fluorescence(SXRF). One was on the piston top and the other on the piston land, termed PTCD and PLCD, respectively. For the PTCD sample, the 97% residue in the TGA and 1.4% carbon content in the EA indicated the main compositions of PTCD were metal salts or oxides and ashes, significantly different from the previous findings of the highest carbon content in deposits from the small four stroke engines. The different chemical content between PTCD and PLCD implied higher thermal load in the LSTS marine diesel engine led to a nearly complete thermal decomposition of PTCD. The higher calcium content in PTCD and PLCD indicated the additives of cylinder oil should be the main source of metal content of PTCD and PLCD. Calcium distribution in the SXRF results was indicative of the potential layered structure in PTCD and PLCD. In addition, the appearance of iron on the surface against the piston in PTCD and PLCD indicated iron oxides formation between carbon deposit and piston materials. | ZHANG XuSheng ZENG XiangMing SUN XiuCheng DENG Biao PENG GuanYun XIE HongLan WU ZhiJun XIAO TiQiao | 2015 | Science China(Technological Sciences)2015，58，10： | 2 |
| 3 | Redefinition to bilayer osmotic pump tablets as subterranean river system within mini-earth via three-dimensional structure mechanism显示文摘Defining and visualizing the three-dimensional(3 D) structures of pharmaceuticals provides a new and important tool to elucidate the phenomenal behavior and underlying mechanisms of drug delivery systems. The mechanism of drug release from complex structured dosage forms, such as bilayer osmotic pump tablets, has not been investigated widely for most solid 3 D structures. In this study, bilayer osmotic pump tablets undergoing dissolution, as well as after dissolution in a desiccated solid state were examined, and visualized by synchrotron radiation micro-computed tomography(SR-μCT). In situ formed 3 D structures at different in vitro drug release states were characterized comprehensively. A distinct movement pattern of NaCl crystals from the push layer to the drug layer was observed, beneath the semi-permeable coating in the desiccated tablet samples. The 3 D structures at different dissolution time revealed that the pushing upsurge in the bilayer osmotic pump tablet was directed via peripheral“roadways”. Typically, different regions of the osmotic front, infiltration region, and dormant region were classified in the push layer during the dissolution of drug from tablet samples. According to the observed3 D microstructures, a “subterranean river model” for the drug release mechanism has been defined to explain the drug release mechanism. | Abi Maharjan Hongyu Sun Zeying Cao Ke Li Jinping Liu Jun Liu Tiqiao Xiao Guanyun Peng Junqiu Ji Peter York Balmukunda Regmi Xianzhen Yin Jiwen Zhang Li Wu | 2022 | Acta Pharmaceutica Sinica B2022，12，5： | 1 |
| 4 | Visualizing Complex Anatomical Structure in Bamboo Nodes Based on X-ray Microtomography显示文摘In recent years,bamboo has been widely used in a broad range of applications,a thorough understanding of the structural characteristics of bamboo nodes is essential for better processing and manufacturing of biomimetic materials.This study investigated the complex anatomical structure for the nodes of two bamboo species,Indocalamus latifolius(Keng)McClure and Shibataea chinensis Nakai,using a high-resolution X-ray microtomography(μCT).The results show that the vascular bundle system in the nodal region of I.latifolius and S.chinensis is a net-like structure composed of horizontal and axial vascular bundles.Furthermore,the fiber sheath surrounding metaxylem vessels tended to be shorter in the tangential direction.This structure of bamboo nodes facilitates the tangential and axial transport of moisture and nutrients.The anatomical structure of I.latifolius and S.chinensis nodes has obvious differences,especially in the arrangement of vascular bundles.Vascular bundle frequency was significantly higher in S.chinensis nodes than in I.latifolius nodes.These findings indicate thatμCT is a nondestructive three-dimensional imaging method that can used to examine the anatomical structure of bamboo nodes. | Elin Xiang Shumin Yang Chunjie Cao Xinge Liu Guanyun Peng Lili Shang Genlin Tian Qianli Ma Jianfeng Ma | 2021 | Journal of Renewable Materials2021，9，9： | 0 |
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