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64篇 您的检索式:作者名="Grygoruk"
    题名 作者 年代 出处 被引量
1High concentration of antimitochondrial antibodies predicts progressive primary biliary cirrhosis显示文摘AIM: To evaluate the serum concentration of antimitochondrial antibodies (AMAs) as a prognostic indicator of progressive primary biliary cirrhosis (pPBC).METHODS: Serum concentrations of AMA subtypes (anti-M2, anti-M4, and anti-M9), biochemical indices of liver function and Mayo risk factor (MRF) were determined in 30 women with diagnosed primary biliary cirrhosis (PBC) selected among 348 females with elevated alkaline phosphatase but without signs of hepatic decompensation.They were followed up for 5 years for possible development of hepatic decompensation.RESULTS: Anti-M2 concentration was significantly correlated with bilirubin and albumin levels as well as MRF, whereas anti-M4 was significantly correlated with albumin level, prothrombin time and MRF. During the 5-year follow-up, progressive PBC (pPBC) was diagnosed in 3 among 23 patients available for evaluation. These 3patients were positive for both anti-M2 and anti-M4.Anti-M2 serum concentration exceeded 1 300 RU/mL in patients with pPBC and only in 1 among 20 non-progressive PBC persons (5%). Anti-M4 serum concentration exceeded 400 RU/mL in 2 of the progressive patients and none in the non-progressive group. In contrast, anti-M9 serum concentration was below 100 RU/mL in all patients with pPBC, and higher than 100 RU/mL in 11 women (55%)among the non-progressive group.CONCLUSION: Females with elevated alkaline phosphatase and high anti-M2 and anti-M4 concentrations are at a high risk for developing pPBC. Quantitative AMA detection should be considered as a method for early diagnosis of pPBC.Robert Flisiak Maria Pelszynska Danuta Prokopowicz Magdalena Rogalska Urszula Grygoruk 2005World Journal of Gastroenterology2005,11,36:16
2Trafficking of vesicular neurotransmitter transporters显示文摘Fei H Grygoruk A Brooks ES 2008Traffic2008,9,9:1
3Rescue ICSI of unfertilized o- ocytes after IVF 显示文摘Kuczynski W Dhont M Grygoruk C 2002Hum Reprod2002,17,9:1
4Rescue ICSI of unfertilized oocytes after IVF显示文摘Kuczyński W Dhont M Grygoruk C 2002Hum Reprod2002,17,:1
5Rescue ICSI of unfertileized oocytes after IVF显示文摘Kuczynski W Dhont M Grygoruk C 2002Hum Reprod2002,17,9:1
6Rescue ICSI of unfertilized oocytes after IVF 显示文摘Kuczynski W Dhont M Grygoruk C 2002Hum Reprod2002,17,9:1
7Rescue ICSI of unfertilized oocytes after in vitro fertilization 显示文摘Kucznski W Dhont M Grygoruk C 2002Hum Reprod2002,17,9:1
8Rescue ICSI of unfertilized oocytes after IVF 显示文摘Kuczynski W Dhont M Grygoruk C 2002Hum Reprod2002,17,:1
9Rescue ICSI of unfertilized oocytes after IVF显示文摘Kuczynski W Dhont M Grygoruk C 2002Hum Reprod2002,17,9:1
10Rescue ICSI of unfertilized oocytes after IVF显示文摘Kuczynski W Dhont M Grygoruk C 2002Hum Reprod2002,17,9:1
11Rescue ICSI of unfertilized oocytes after IVF 显示文摘Kuczynski W Dhont M Grygoruk C 2002Hum Reprod2002,17,9:1
12Rescue ICSI of unfertilized oocytes after IVF显示文摘Kuczynski W Dgont M Grygoruk C 2002Hum Reprod2002,17,9:1
13Rescue ICSI of unfertilized oocytes after IVF显示文摘Kuczynski W Dhont M Grygoruk C 2002Hum Reprod2002,17,9:1
14Rescue ICSI of unfertilized oocytes after IVF显示文摘Kuczynski W Dhont M Grygoruk C 2002Hum Reprod2002,17,9:1
15Rescue ICSI of unfertilized oocytes after IVF显示文摘Kuczyflski W Dhont M Grygoruk C 2002Hum Reprod2002,17,:1
16Rescue ICSI of unfertilized oocytes after IVF显示文摘Kuczyflski W Dhont M Grygoruk C 2002Hum Reprod2002,17,9:1
17Rescue ICSI of unfertilized ooeytes after IVF显示文摘Kuczynski W Dhont M Grygoruk C 2002Hum Reprod2002,17,9:1
18Rescue ICSI of unfertilized oocytes after IVF显示文摘Kuczyński W Dhont M Grygoruk C 2002Hum Reprod2002,17,9:1
19Rescue ICSI of unfertilized oocytes after IVF显示文摘Kuczyfiski W Dhont M Grygoruk C 2002Hum Reprod2002,17,9:1
20Rescue ICSI of unfertilized oocytes after IVF显示文摘Kuczynski W Dhont M Grygoruk C 0,,09:1
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