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| 1 | Para-aortic node involvement is not an independent predictor of survival after resection for pancreatic cancer显示文摘AIM To analyze the importance of para-aortic node status in a series of patients who underwent pancreaticoduodenectomy(PD)in a single Institution.METHODS Between January 2000 and December 2012,151patients underwent PD with para-aortic node dissection for pancreatic adenocarcinoma in our Institution.Patients were divided into two groups:patients with negative PALNs(PALNs-),and patients with metastatic PALNs(PALNs+).Pathologic factors,including stage,nodal status,number of positive nodes and lymph node ratio,invasion of para-aortic nodes,tumor’s grading,and radicality of resection were studied by univariate and multivariate analysis.Survival curves were constructed with Kaplan-Meier method and compared with Log-rank test:significance was considered as P<0.05.RESULTS A total of 107 patients(74%)had nodal metastases.Median number of pathologically assessed lymph nodes was 26(range 14-63).Twenty-five patients(16.5%) had para-aortic lymph node involvement.Thirty-three patients(23%)underwent R1 pancreatic resection.Onehundred forty-one patients recurred and died for tumor recurrence,one is alive with recurrence,and 9 are alive and free of disease.Overall survival was significantly influenced by grading(P=0.0001),radicality of resection(P=0.001),stage(P=0.03),lymph node status(P=0.04),para-aortic nodes metastases(P=0.02).Multivariate analysis showed that grading was an independent prognostic factor for overall survival(P=0.0001),while grading(P=0.0001)and radicality of resection(P=0.01)were prognostic parameters for disease-free survival.Number of metastatic nodes,node ratio,and para-aortic nodes involvement were not independent predictors of disease-free and overall survival.CONCLUSION In this experience,lymph node status and para-aortic node metastases were associated with poor survival at univariate analysis,but they were not independent prognostic factors. | Cosimo Sperti Mario Gruppo Stella Blandamura Michele Valmasoni Gioia Pozza Nicola Passuello Valentina Beltrame Lucia Moletta | 2017 | World Journal of Gastroenterology2017，23，24： | 5 |
| 2 | Common femoral artery endarterectomy for occlusive disease:an 8-year single-center prospective study显示文摘 | Ballotta E Gruppo M Mazzalai F | 2010 | Surgery2010，147，2： | 1 |
| 3 | Predictors ofneck bleeding after eversion carotid endarterectomy 显示文摘 | Baracchini C Gruppo M Mazzalai F | 2011 | JVase Surg2011，54，： | 1 |
| 4 | Familial analysis of panic disor- der and agoraphobia显示文摘 | Gruppo haliano Disturbi dgmsia | 1989 | J Affect Disord1989，17，： | 1 |
| 5 | GISSI-3:Effects of lisinopril and transdermal glyceryl trinitrate singly and together on 6-week mortality and ventricular function after acute myocardial infarction显示文摘 | Gruppo Italiano per Io Studio della Soprawivenza nell'Infarto Miocardico | 2009 | Lancet2009，343，： | 1 |
| 6 | Preclinical testing of the nitroimidazopyran PA-284 for activity againstM ycobacterium tuberculosis in a series of in vitro and in vivo models显示文摘 | LenaertsAJ Gruppo V Marietta KS | 2005 | 1 Antimicrob Agents Chemother2005，49，22： | 1 |
| 7 | Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction显示文摘 | | 1986 | Lancet1986，1，： | 1 |
| 8 | Predictors of neck bleeding after eversion carotid endarterectomy显示文摘 | Baracchini C Gruppo M Mazzalai F | | 0，，03： | 1 |
| 9 | GISSI-2: a factorial randomised trial of alteplase versus streptokinase and heparin versus no heparin among 12 490 patients with acute myocardial infarction 显示文摘 | Gruppo Italiano perlo Studio della Sopravvivenza nell' Infarto Miocardico | 1990 | Lancet1990，336，8707： | 1 |
| 10 | The plasminogen activator inhibitor-1 gene, hypofibrinolysis, and osteoneerosis显示文摘 | GLUECK C J FONTAINE R N GRUPPO R | 1999 | Clin Orthop Relat Res1999，366，： | 1 |
| 11 | Mycobacteria lacking the RD1 region do not induce necrosis in the lungs of mice lacking interferon-gamma 显示文摘 | Junqueira-Kipnis A P Basaraba R J Gruppo V | 2006 | Immunology2006，119，2： | 1 |
| 12 | Rapid microbiologic and pharmacologic evaluation of experimental compounds against Mycobacterium tuberculosis显示文摘 | Gruppo V Johnson CM Marietta KS Scherman H Zink EE Crick DC | 2006 | Antimicrob Agents Chemother2006，50，4： | 1 |
| 13 | Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction显示文摘 | Gruppo Italiano per lo Studio della Streptochinasi nell Infarto Miocar-Dico(GISSI) | 1986 | Lancet1986，327，8478： | 1 |
| 14 | Randomised placebo- controlled trial of effect of ramipril on decline in glomerular filtration rate and risk of terminal renal failure in proteinuric, non - diabetic nephropathy显示文摘 | The GISEN Group (Gruppo Italiano di Studi Epidemiologici in Nefrologia) | 1997 | Lancet1997，349，9069： | 1 |
| 15 | Preoperative 18-FDG PET predicts survivalin resectable pancreatic cancer显示文摘 | Beltrame V Gruppo M Merigliano S | 2015 | Eur J Surg Oncol2015，41，1： | 1 |
| 16 | Atrial fibrillation detection after cryptogenic stroke显示文摘 | Wu MA Seannella E Gruppo di Autoformazione Metodologica (GRAM) | 2014 | Intern Emerg Med2014，9，8： | 1 |
| 17 | Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction : ISIS-2 显示文摘 | Gruppo Italiano per lo Studio della Streptochinasi nell Infarto Miocardico (GISSI) | 1988 | Lancet1988，2，8607： | 1 |
| 18 | Extra - gastrointestinal stromal tumor of the pancreas : Case report and review of the litera- ture显示文摘 | Beltrame V Gruppo M Pastorelli D | 2014 | World J Surg Onco12014，12，： | 1 |
| 19 | A factorical randomized trial of alteplase versus stretokinase and heparin versus no heprin among l2490 patients with AMI显示文摘 | | 1990 | Lancet1990，336，： | 1 |
| 20 | CompLications during the acute phase of traumatic spinal cord lesions显示文摘 | Aito S Gruppo Italiano Studio Epidemiologico Mielolesioni GISEM Group | 2003 | Spinal Cord2003，41，11： | 1 |
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