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您的检索式：作者名="Gregor Roth"
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| 1 | Predictors of disease severity in ulcerative colitis patients from Southwestern Ontario显示文摘AIM:To understand the demographic characteristics of patients in Southwestern Ontario,Canada with ulcerative colitis(UC)in order to predict disease severity. METHODS:Records from 1996 to 2001 were exam- ined to create a database of UC patients seen in the London Health Sciences Centre South Street Hospital Inflammatory Bowel Disease Clinic.To be included, patients'charts were required to have information of their disease presentation and a minimum of 5 years of follow-up.Charts were reviewed using standardized data collection forms.Disease severity was generated during the chart review process,and non-endoscopic Mayo Score criteria were collected into a composite. RESULTS:One hundred and two consecutive patients'data were entered into the database.Demographic analyses revealed that 51%of the patients were male, the mean age at diagnosis was 39 years,13.7%had a first degree relative with inflammatory bowel disease (IBD),61.8%were nonsmokers and 24.5%were ex-smokers.In 22.5%of patients the disease was limited to the rectum,in 21.6%disease was limited to the sigmoid colon,in 22.5%disease was limited to the left colon,and 32.4%of patients had pancolitis. Standard multiple regression analysis which regressed a composite of physician global assessment of disease severity,average number of bowel movements,and average amount of blood in bowel movements on year of diagnosis and age at time of diagnosis was significant,R 2=0.306,F(7,74)=4.66,P<0.01. Delay from symptoms to diagnosis of UC,gender, family history of IBD,smoking status and disease severity at the time of diagnosis didnot significantly predict the composite measure. CONCLUSION:UC severity is associated with younger age at diagnosis and year of diagnosis in a longitudinal cohort of UC patients,and may identify prognostic UC indicators. | Lee S Roth Nilesh Chande Terry Ponich Maya L Roth James Gregor | 2010 | World Journal of Gastroenterology2010，16，2： | 4 |
| 2 | 服务器负载均衡架构之应用层负载均衡——服务器集群的高扩展性和高可用性显示文摘本文的第一部分介绍了传输层服务器负载均衡的解决方案,例如基于TCP/IP的负载均衡器等等,并分析了这些方案的优缺点。TCP/IP层的负载均衡将TCP连接分散到服务器集群中众多真实的服务器上。通常情况下,特别是对于静态的网站而言,采用这种方案就可以满足需求了。不过,动态网站常常需要更高层(相对传输层来说)的负载均衡技术。例如,如果服务器端的应用必须处理缓存或者应用会话数据,那么如何有效进行会话保持就要作为考虑重点了。在第二部分中,我将讨论如何在应用层实现服务器负载均衡,以满足众多动态网站的需求。 | Gregor Roth 李明 | 2009 | 程序员2009，，1： | 3 |
| 3 | 服务器负载均衡架构之传输层负载均衡——服务器集群的高扩展性和高可用性显示文摘负载均衡是一种使服务器集群在客户端表现为单台服务器的技术,服务器集群通过这种技术实现了高扩展性和高可用性。本文中,作者Gregor Roth介绍了负载均衡的基础,并讨论了传输层负载均衡架构的优缺点。 | Gregor Roth 李明 | 2008 | 程序员2008，，12： | 0 |
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