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144篇 您的检索式:作者名="Grafe M"
    题名 作者 年代 出处 被引量
1普罗布考和抗氧化维生素不影响体外实验条件下内皮细胞的白细胞粘附显示文摘为探讨预防动脉粥样硬化的药物普罗布考、维生素C和维生素E是否抑制内皮细胞表面粘附分子表达和白细胞—内皮细胞的粘附 ,以及这种抑制是否通过影响核因子 -κB的活性来实现的 ,在液体流动小室中进行细胞粘附实验 ;用ELISA方法测定内皮细胞粘附分子E -选择素的表达 ;用电泳迁移率分析测定内皮细胞核因子 -κB的活性。经肿瘤坏死因子α刺激的内皮细胞核因子 -κB活性增加 ,粘附分子E -选择素的表达上调 (是基础水平的 3.5倍 ) ,其表面HL6 0细胞的粘附增加 (是基础水平的 4~ 2 6倍 ) ,而抗氧化剂PDTC使所有这些变化都受到抑制。PDTC浓度为 18μmol L时对粘附分子E -选择素的表达呈最大半抑制 ;PDTC浓度为 5 2 μmol L时对内皮细胞表面HL6 0细胞的粘附呈最大半抑制。普罗布考、维生素C和维生素E对肿瘤坏死因子α诱导的粘附分子表达和HL6 0细胞与内皮细胞的粘附没有作用 ;对核因子 -κB的活性没有影响。临床上常用的这三种抗氧化剂并未影响作为动脉粥样硬化始动机制之一的E -选择素介导的白细胞 -内皮细胞粘附水平。黄虔 Grfe M Grafe K Fleck E 2001中国动脉硬化杂志2001,9,2:2
2CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells 显示文摘Herm V Slupsky JR Grafe M 1998Nature1998,391,6667:1
3Angiotensin Ⅱ-induced leukocyte adhesion on human coronary endothelial cells is mediated by E-selectin显示文摘Grafe M Auch Schwelk W Zakrzewicz A 1997Circ Res1997,81,5:1
4CD40 ligand is selectively expressed on CD4^+ T cells and platelets:implications for CD40-CD40L signalling in atherosclerosis显示文摘Buchner K Henn V Grafe M 2003J Pathol2003,201,2:1
5Angiotensin Ⅱ-induced leukocyte adhesionon human coronary endothelial cells is mediated by E-selectin显示文摘Grafe M Auch-Schwelk W Zakrzewicz A 1997Circ Res1997,81,:1
6Treatment of psoriasis with interleukin-10显示文摘Reich K Bruck M Grafe A 1998J Invest Dermatol1998,111,6:1
7Treatment of psoriasis with interleukin-10显示文摘Reich K Bruck M Grafe A 1998J Invest Dermatol1998,111,6:1
8AngiotensinⅡ induced leukocyte adhesion on human coronary endothelial cells is mediated by E selectin显示文摘Grafe M Auch-Schwelk W Zakrewicz A 1997Circ Res1997,81,5:1
9CD40 ligand on activated platelets triggers an infammatory reaction of endothelial cell显示文摘Henn V Slupsky J Grafe M 1998J Nature1998,391,:1
10CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells 显示文摘Henn V Slupsky JR Grafe M 1998Nature1998,391,:1
11CD40 ligand on activated platelets triggers an intlammatory reaction of endothelial cells 显示文摘Henn V Slupsky JR Grafe M 1998Nature1998,391,6667:1
12High temperature solar thermal processing of Zn(s) and CO from ZnO(s) and C(gr) using Ti2O3 and TiO2显示文摘Palumbo R D Campbell M B Grafe T 1992Energy Int J1992,17,3:1
13Adsorption of arsenate (V) and arsenite (III) on goethite in the presence and absence of dissolved organic carbon显示文摘GRAFE M EICK M J GROSS P R 2001Soil Science Society of America Journal2001,65,6:1
14Adsorption of arsenate (Ⅴ) and arsenite (Ⅲ) on goethite in the presence and absence of dissolved organic carbon显示文摘Grafe M Eick M J Grossl P R 2001Soil Sci Soc Am J2001,65,:1
15Human cardiac microvascular and macrovascular endothelial cells respond differently to oxidatively modified LDL显示文摘Grafe M Auch-Schwelk W Hertel H 1998Atherosclerosis1998,137,2:1
16Adsorption of arsenate and arsenite on ferrihydrite in the presence and absence of dissolved organic carbon显示文摘Grafe M Eick M J Grossl P R 2002Journal of Environmental Quality2002,31,4:1
17CD40 ligand on activated platelets triggers an inflammayory reaction of endothelial cells显示文摘Henn V Slupsky JR Grafe M 1998Nature1998,391,6667:1
18CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells显示文摘HENN V SLUPSKY J R GRAFE M 1998Nature1998,391,6667:1
19Angiotensin Ⅰinduced leukocyte adhesion on human coronary endothelial cells is mediated by E-selectin显示文摘 Auch-Schwelk W Zakrzewicz A 1997Circ Res1997,81,5:1
20CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells显示文摘Henn V Slupsky JR Grafe M 0,,:1
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